PMID- 30251484
OWN - NLM
STAT- MEDLINE
DCOM- 20200309
LR  - 20200309
IS  - 1560-2281 (Electronic)
IS  - 1083-3668 (Print)
IS  - 1083-3668 (Linking)
VI  - 23
IP  - 9
DP  - 2018 Sep
TI  - Economical and compact briefcase spectral-domain optical coherence tomography 
      system for primary care and point-of-care applications.
PG  - 1-11
LID - 10.1117/1.JBO.23.9.096003 [doi]
LID - 096003
AB  - Development of low-cost and portable optical coherence tomography (OCT) systems 
      is of global interest in the OCT research community. Such systems enable utility 
      broadly throughout a clinical facility, or in remote areas that often lack 
      clinical infrastructure. We report the development and validation of a low-cost, 
      portable briefcase spectral-domain optical coherence tomography (SD-OCT) system 
      for point-of-care diagnostics in primary care centers and/or in remote settings. 
      The self-contained briefcase OCT contains all associated optical hardware, 
      including light source, spectrometer, hand-held probe, and a laptop. 
      Additionally, this system utilizes unique real-time mosaicking of surface video 
      images that are synchronized with rapid A-scan acquisition to eliminate the need 
      for lateral scanning hardware, and enable the construction of cross-sectional 
      B-mode images over extended lateral distances. The entire briefcase system weighs 
      9 kg and costs  approximately USD$8000 using off-the-shelf components. System performance was 
      validated by acquiring images of in vivo human skin on the fingertip, palm, and 
      nail fold. The efficiency, portability, and low-cost enable accessibility and 
      utility in primary care centers and low-resource settings.
CI  - (2018) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).
FAU - Dsouza, Roshan
AU  - Dsouza R
AD  - University of Illinois at Urbana-Champaign, Beckman Institute for Advanced 
      Science and Technology, U, United States.
FAU - Won, Jungeun
AU  - Won J
AD  - University of Illinois at Urbana-Champaign, Beckman Institute for Advanced 
      Science and Technology, U, United States.
AD  - University of Illinois at Urbana-Champaign, Department of Bioengineering, Urbana, 
      Illinois, United States.
FAU - Monroy, Guillermo L
AU  - Monroy GL
AD  - University of Illinois at Urbana-Champaign, Beckman Institute for Advanced 
      Science and Technology, U, United States.
AD  - University of Illinois at Urbana-Champaign, Department of Bioengineering, Urbana, 
      Illinois, United States.
FAU - Spillman, Darold R
AU  - Spillman DR
AD  - University of Illinois at Urbana-Champaign, Beckman Institute for Advanced 
      Science and Technology, U, United States.
FAU - Boppart, Stephen A
AU  - Boppart SA
AD  - University of Illinois at Urbana-Champaign, Beckman Institute for Advanced 
      Science and Technology, U, United States.
AD  - University of Illinois at Urbana-Champaign, Department of Bioengineering, Urbana, 
      Illinois, United States.
AD  - University of Illinois at Urbana-Champaign, Department of Electrical and Computer 
      Engineering, Urban, United States.
LA  - eng
GR  - R01 CA213149/CA/NCI NIH HHS/United States
GR  - R01 EB013723/EB/NIBIB NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PL  - United States
TA  - J Biomed Opt
JT  - Journal of biomedical optics
JID - 9605853
SB  - IM
MH  - Equipment Design
MH  - Hand/diagnostic imaging
MH  - Humans
MH  - *Point-of-Care Systems
MH  - *Primary Health Care
MH  - Skin/diagnostic imaging
MH  - Spectrum Analysis/instrumentation
MH  - Tomography, Optical Coherence/*instrumentation
PMC - PMC6170142
OTO - NOTNLM
OT  - diagnostics
OT  - handheld
OT  - optical coherence tomography
OT  - point-of-care
OT  - spectrometers
OT  - system development
EDAT- 2018/09/27 06:00
MHDA- 2020/03/10 06:00
PMCR- 2019/09/24
CRDT- 2018/09/26 06:00
PHST- 2018/03/14 00:00 [received]
PHST- 2018/08/29 00:00 [accepted]
PHST- 2018/09/26 06:00 [entrez]
PHST- 2018/09/27 06:00 [pubmed]
PHST- 2020/03/10 06:00 [medline]
PHST- 2019/09/24 00:00 [pmc-release]
AID - JBO-180158RR [pii]
AID - 180158RR [pii]
AID - 10.1117/1.JBO.23.9.096003 [doi]
PST - ppublish
SO  - J Biomed Opt. 2018 Sep;23(9):1-11. doi: 10.1117/1.JBO.23.9.096003.