PMID- 30251499
OWN - NLM
STAT- MEDLINE
DCOM- 20181018
LR  - 20181018
IS  - 1872-2059 (Electronic)
IS  - 1000-8713 (Linking)
VI  - 36
IP  - 8
DP  - 2018 Aug 8
TI  - [Determination of 28 exogenous medicines and endogenous components in herbal 
      drink using high performance liquid chromatography].
PG  - 758-765
LID - 10.3724/SP.J.1123.2018.02005 [doi]
AB  - A high performance liquid chromatographic method for the determination of 28 
      exogenous medicines and endogenous components in the herbal drink was developed. 
      The samples were extracted ultrasonically with methanol-water (70:30, v/v), and 
      the extracts were separated in a Thermo Accucore C18 column (100 mmx4.6 mm, 2.6 
      mum) with methanol-acetonitrile-20 mmol/L ammonium acetate solution (pH 4.2) as 
      the mobile phases by gradient elution. The flow rate was 1.2 mL/min and the 
      column temperature was 35℃. The detection wavelengths were 254 nm and 220 nm. 
      Quantification analysis was performed by the external standard method. The result 
      showed the compounds had a good linear relationship in the range of 1-100 mg/L, 
      and the correlation coefficients (r) were not less than 0.999. The limits of 
      detection (LODs) of the 28 compounds were 1-10 mg/kg in the liquid sample and 
      20-200 mg/kg in the solid sample. The average recoveries of the 28 compounds in 
      the liquid and solid samples were in the ranges of 88.8%-118.6% and 92.7%-112.3% 
      with the relative standard deviations (RSDs) of 0.1%-6.7% and 0.1%-6.4%, 
      respectively. The method was applied to analyze 456 herbal drink samples, and 55 
      positive samples were found. The positive rate was 12.1%. The developed method 
      was simple and reliable, and it was suitable for the determination of 28 
      components in the herbal drink.
FAU - He, Jiawen
AU  - He J
AD  - Guangdong Institute for Drug Control, Guangzhou 510180, China.
FAU - Wen, Jiaxin
AU  - Wen J
AD  - Guangdong Institute for Drug Control, Guangzhou 510180, China.
FAU - Lai, Yuhong
AU  - Lai Y
AD  - Guangdong Institute for Drug Control, Guangzhou 510180, China.
FAU - Cao, Yajing
AU  - Cao Y
AD  - Guangdong Institute for Drug Control, Guangzhou 510180, China.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Pharmaceutical Preparations)
SB  - IM
MH  - Beverages/*analysis
MH  - Chromatography, High Pressure Liquid
MH  - Food Contamination/*analysis
MH  - Limit of Detection
MH  - Pharmaceutical Preparations/*analysis
OTO - NOTNLM
OT  - fused core particle column
OT  - herbal drink
OT  - high performance liquid chromatography (HPLC)
OT  - illegally added medicine
EDAT- 2018/09/27 06:00
MHDA- 2018/10/20 06:00
CRDT- 2018/09/26 06:00
PHST- 2018/09/26 06:00 [entrez]
PHST- 2018/09/27 06:00 [pubmed]
PHST- 2018/10/20 06:00 [medline]
AID - 10.3724/SP.J.1123.2018.02005 [doi]
PST - ppublish
SO  - Se Pu. 2018 Aug 8;36(8):758-765. doi: 10.3724/SP.J.1123.2018.02005.