PMID- 30252028
OWN - NLM
STAT- MEDLINE
DCOM- 20201001
LR  - 20201001
IS  - 1873-734X (Electronic)
IS  - 1010-7940 (Linking)
VI  - 55
IP  - 3
DP  - 2019 Mar 1
TI  - Effect of an intra-aortic balloon pump with venoarterial extracorporeal membrane 
      oxygenation on mortality of patients with cardiogenic shock: a systematic review 
      and meta-analysisdagger.
PG  - 395-404
LID - 10.1093/ejcts/ezy304 [doi]
AB  - An intra-aortic balloon pump (IABP) concomitant with venoarterial extracorporeal 
      membrane oxygenation (VA-ECMO) is frequently used to support patients with 
      refractory cardiogenic shock (CS). Because of the lack of evidence of the 
      adjunctive benefit, the goal of the study was to compare the effect of VA-ECMO 
      plus IABP with that of VA-ECMO alone. Systematic searches were conducted to 
      identify studies using PubMed, Embase, the Cochrane Library and the International 
      Clinical Trials Registry Platform. Studies reporting on patients with adult CS 
      treated with VA-ECMO plus IABP or VA-ECMO alone were identified and included. The 
      primary outcome was in-hospital death. The secondary outcomes included 
      neurological, gastrointestinal and limb-related complications. The study protocol 
      was registered at PROSPERO (CRD42017069259). A total of 29 studies comprising 
      4576 patients were included. The pooled in-hospital deaths of patients on VA-ECMO 
      were 1441/2285 (63.1%) compared with 1339/2291 (58.4%) for patients with 
      adjunctive IABP. VA-ECMO plus IABP was associated with decreased in-hospital 
      deaths [risk ratio (RR) 0.90; 95% confidence interval (CI) 0.85-0.95; 
      P < 0.0001]. Moreover, IABP was related to decreased in-hospital deaths of 
      patients with extracorporeal cardiopulmonary resuscitation, postcardiotomy CS and 
      ischaemic heart disease (RR 0.78; 95% CI 0.64-0.95; P = 0.01; RR 0.91; 95% CI: 
      0.85-0.98; P = 0.008; RR 0.83; 95% CI 0.73-0.96, P = 0.009). Neurological, 
      gastrointestinal and limb-related complications did not differ significantly 
      between patients on ECMO with and without concurrent IABP. VA-ECMO plus IABP was 
      associated with decreased in-hospital deaths in patients with CS.
CI  - (c) The Author(s) 2018. Published by Oxford University Press on behalf of the 
      European Association for Cardio-Thoracic Surgery. All rights reserved.
FAU - Li, Yongnan
AU  - Li Y
AD  - Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou 
      University, Lanzhou, China.
AD  - Department of Cardiopulmonary Bypass, State Key Laboratory of Cardiovascular 
      Medicine, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese 
      Academy of Medical Science and Peking Union Medical College, Beijing, China.
FAU - Yan, Shujie
AU  - Yan S
AD  - Department of Cardiopulmonary Bypass, State Key Laboratory of Cardiovascular 
      Medicine, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese 
      Academy of Medical Science and Peking Union Medical College, Beijing, China.
FAU - Gao, Sizhe
AU  - Gao S
AD  - Department of Cardiopulmonary Bypass, State Key Laboratory of Cardiovascular 
      Medicine, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese 
      Academy of Medical Science and Peking Union Medical College, Beijing, China.
FAU - Liu, Mingyue
AU  - Liu M
AD  - Department of Cardiopulmonary Bypass, State Key Laboratory of Cardiovascular 
      Medicine, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese 
      Academy of Medical Science and Peking Union Medical College, Beijing, China.
FAU - Lou, Song
AU  - Lou S
AD  - Department of Cardiopulmonary Bypass, State Key Laboratory of Cardiovascular 
      Medicine, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese 
      Academy of Medical Science and Peking Union Medical College, Beijing, China.
FAU - Liu, Gang
AU  - Liu G
AD  - Department of Cardiopulmonary Bypass, State Key Laboratory of Cardiovascular 
      Medicine, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese 
      Academy of Medical Science and Peking Union Medical College, Beijing, China.
FAU - Ji, Bingyang
AU  - Ji B
AD  - Department of Cardiopulmonary Bypass, State Key Laboratory of Cardiovascular 
      Medicine, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese 
      Academy of Medical Science and Peking Union Medical College, Beijing, China.
FAU - Gao, Bingren
AU  - Gao B
AD  - Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou 
      University, Lanzhou, China.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Systematic Review
PL  - Germany
TA  - Eur J Cardiothorac Surg
JT  - European journal of cardio-thoracic surgery : official journal of the European 
      Association for Cardio-thoracic Surgery
JID - 8804069
SB  - IM
MH  - Combined Modality Therapy
MH  - Extracorporeal Membrane Oxygenation/*methods
MH  - Humans
MH  - Intra-Aortic Balloon Pumping/*methods
MH  - Shock, Cardiogenic/*mortality/*surgery/therapy
OTO - NOTNLM
OT  - Cardiogenic shock
OT  - Intra-aortic balloon pumping
OT  - Meta-analysis
OT  - Venoarterial extracorporeal membrane oxygenation
EDAT- 2018/09/27 06:00
MHDA- 2020/10/02 06:00
CRDT- 2018/09/26 06:00
PHST- 2018/05/23 00:00 [received]
PHST- 2018/07/26 00:00 [revised]
PHST- 2018/07/31 00:00 [accepted]
PHST- 2018/09/27 06:00 [pubmed]
PHST- 2020/10/02 06:00 [medline]
PHST- 2018/09/26 06:00 [entrez]
AID - 5106356 [pii]
AID - 10.1093/ejcts/ezy304 [doi]
PST - ppublish
SO  - Eur J Cardiothorac Surg. 2019 Mar 1;55(3):395-404. doi: 10.1093/ejcts/ezy304.