PMID- 30254575
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 1662-5153 (Print)
IS  - 1662-5153 (Electronic)
IS  - 1662-5153 (Linking)
VI  - 12
DP  - 2018
TI  - Neurobiology of Wild and Hatchery-Reared Atlantic Salmon: How Nurture Drives 
      Neuroplasticity.
PG  - 210
LID - 10.3389/fnbeh.2018.00210 [doi]
LID - 210
AB  - Life experiences in the rearing environment shape the neural and behavioral 
      plasticity of animals. In fish stocking practices, the hatchery environment is 
      relatively stimulus-deprived and does not optimally prepare fish for release into 
      the wild. While the behavioral differences between wild and hatchery-reared fish 
      have been examined to some extent, few studies have compared neurobiological 
      characteristics between wild and hatchery-reared individuals. Here, we compare 
      the expression of immediate early gene cfos and neuroplasticity marker 
      brain-derived neurotrophic factor (bdnf) in telencephalic subregions associated 
      with processing of stimuli in wild and hatchery-reared Atlantic salmon at basal 
      and 30 min post (acute) stress conditions. Using in situ hybridization, we found 
      that the expression level of these markers is highly specific per neuronal region 
      and affected by both the origin of the fish, and exposure to acute stress. 
      Expression of cfos was increased by stress in all brain regions and cfos was more 
      highly expressed in the Dlv (functional equivalent to the mammalian hippocampus) 
      of hatchery-reared compared to wild fish. Expression of bdnf was higher overall 
      in hatchery fish, while acute stress upregulated bdnf in the Dm (functional 
      equivalent to the mammalian amygdala) of wild, but not hatchery individuals. Our 
      findings demonstrate that the hatchery environment affects neuroplasticity and 
      neural activation in brain regions that are important for learning processes and 
      stress reactivity, providing a neuronal foundation for the behavioral differences 
      observed between wild and hatchery-reared fish.
FAU - Mes, Daan
AU  - Mes D
AD  - Department of Production Animal Clinical Sciences, Norwegian University of Life 
      Sciences, Oslo, Norway.
FAU - von Krogh, Kristine
AU  - von Krogh K
AD  - Department of Basic Sciences and Aquatic Medicine, Norwegian University of Life 
      Sciences, Oslo, Norway.
FAU - Gorissen, Marnix
AU  - Gorissen M
AD  - Department of Animal Ecology and Physiology, Institute of Water and Wetland 
      Research, Radboud University, Nijmegen, Netherlands.
FAU - Mayer, Ian
AU  - Mayer I
AD  - Department of Production Animal Clinical Sciences, Norwegian University of Life 
      Sciences, Oslo, Norway.
FAU - Vindas, Marco A
AU  - Vindas MA
AD  - Uni Environment, Uni Research AS, Bergen, Norway.
AD  - Department of Neurobiology and Physiology, University of Gothenburg, Gothenburg, 
      Sweden.
AD  - Department of Food Safety and Infection Biology, Norwegian University of Life 
      Sciences, Oslo, Norway.
LA  - eng
PT  - Journal Article
DEP - 20180911
PL  - Switzerland
TA  - Front Behav Neurosci
JT  - Frontiers in behavioral neuroscience
JID - 101477952
PMC - PMC6141658
OTO - NOTNLM
OT  - Atlantic salmon
OT  - bdnf
OT  - cfos
OT  - fish stocking
OT  - immediate early gene
OT  - in situ hybridization
OT  - neuroplasticity
EDAT- 2018/09/27 06:00
MHDA- 2018/09/27 06:01
PMCR- 2018/01/01
CRDT- 2018/09/27 06:00
PHST- 2018/04/13 00:00 [received]
PHST- 2018/08/21 00:00 [accepted]
PHST- 2018/09/27 06:00 [entrez]
PHST- 2018/09/27 06:00 [pubmed]
PHST- 2018/09/27 06:01 [medline]
PHST- 2018/01/01 00:00 [pmc-release]
AID - 10.3389/fnbeh.2018.00210 [doi]
PST - epublish
SO  - Front Behav Neurosci. 2018 Sep 11;12:210. doi: 10.3389/fnbeh.2018.00210. 
      eCollection 2018.