PMID- 30258500
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220321
IS  - 1874-1924 (Print)
IS  - 1874-1924 (Electronic)
IS  - 1874-1924 (Linking)
VI  - 12
DP  - 2018
TI  - Hyperbaric Oxygen Therapy in Ischaemic Foot Ulcers in Type 2 Diabetes: A Clinical 
      Trial.
PG  - 80-85
LID - 10.2174/1874192401812010080 [doi]
AB  - BACKGROUND AND AIMS: Several treatment modalities and protocols for ischaemic 
      foot ulcers are available. However, little consensus exists on optimal treatment. 
      The aim of this study was to compare Standard Wound Care (SWC) alone vs. SWC with 
      adjunct hyperbaric oxygen therapy (HBOT) in the treatment of ischaemic Diabetic 
      Foot Ulcers (DFUs). PATIENTS AND METHODS: Twenty-six patients with Type 2 
      Diabetes Mellitus (T2DM) presenting with a newly diagnosed ischaemic foot ulcer 
      were included. These were divided into group A (SWC with adjunct HBOT) and group 
      B (SWC only). Participants were followed every week for 4 weeks and their ulcers 
      were measured for their surface area and depth to assess any change in wound 
      size. RESULTS: Both treatment arms succeeded in reducing ulcer area and depth 
      (p<0.001). However, ulcer area (p<0.001) and depth (p<0.001) exhibited superior 
      improvement in group A. CONCLUSION: Adjunctive HBOT appears to improve wound 
      healing in ischaemic DFUs and merits further study.
FAU - Perren, Sarah
AU  - Perren S
AD  - Faculty of Health Sciences, University of Malta, Msida, Malta.
FAU - Gatt, Alfred
AU  - Gatt A
AD  - Faculty of Health Sciences, University of Malta, Msida, Malta.
FAU - Papanas, Nikolaos
AU  - Papanas N
AD  - Diabetes Centre-Diabetic Foot Clinic, Second Department of Internal Medicine, 
      Democritus University of Thrace, Alexandroupolis, Greece.
FAU - Formosa, Cynthia
AU  - Formosa C
AD  - Faculty of Health Sciences, University of Malta, Msida, Malta.
LA  - eng
PT  - Journal Article
DEP - 20180831
PL  - United Arab Emirates
TA  - Open Cardiovasc Med J
JT  - The open cardiovascular medicine journal
JID - 101480504
PMC - PMC6131315
OTO - NOTNLM
OT  - Diabetic foot ulcer
OT  - HBOT
OT  - Hyperbaric oxygen therapy
OT  - Ischaemia
OT  - Peripheral arterial disease
OT  - Standard wound care
EDAT- 2018/09/28 06:00
MHDA- 2018/09/28 06:01
PMCR- 2018/01/01
CRDT- 2018/09/28 06:00
PHST- 2018/07/09 00:00 [received]
PHST- 2018/07/23 00:00 [revised]
PHST- 2018/08/02 00:00 [accepted]
PHST- 2018/09/28 06:00 [entrez]
PHST- 2018/09/28 06:00 [pubmed]
PHST- 2018/09/28 06:01 [medline]
PHST- 2018/01/01 00:00 [pmc-release]
AID - TOCMJ-12-80 [pii]
AID - 10.2174/1874192401812010080 [doi]
PST - epublish
SO  - Open Cardiovasc Med J. 2018 Aug 31;12:80-85. doi: 10.2174/1874192401812010080. 
      eCollection 2018.