PMID- 30263305
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2092-6456 (Electronic)
IS  - 1226-7708 (Print)
IS  - 1226-7708 (Linking)
VI  - 25
IP  - 2
DP  - 2016
TI  - Anti-allergic effects and related active constituents of mung bean (Vignaradiatus 
      Linn) sprouts.
PG  - 553-559
LID - 10.1007/s10068-016-0077-8 [doi]
AB  - The mung bean (Vigna radiata) is an important food crop with preventative effects 
      against human diseases. The anti-allergic activities of mung bean sprouts of 
      different lengths were evaluated by assaying in vivo antipruritic activity and in 
      vitro hyaluronidase inhibitory effects. After 48 h of growth, sprouts were 
      determined to have the best activity and extracted with petroleum (PeF), ethyl 
      acetate (EaF), and n-butanol (nBF). The active EaF extracts were further assayed 
      for in vivo effects on compound 48/80-induced mast cell degranulation and 
      histamine release, as well as the anti-dinitrophenyl (DNP) IgE-induced passive 
      cutaneous anaphylaxis (PCA) reaction. The main chemical constituents were further 
      analyzed by UV spectrophotometry and high-performance liquid chromatography with 
      tandem mass spectrometric detection (LC/MS/MS). EaF significantly protected 
      against compound 48/80-induced mast cell degranulation and histamine release, and 
      PCA. Flavonoids were determined to be the main contributors to the anti-allergic 
      activity of the EaF extracts.
FAU - Li, Li
AU  - Li L
AD  - 1Beijing Key Laboratory of Plant Resources Research and Development, Beijing 
      Technology and Business University, Beijing, 100048 China. GRID: grid.411615.6. 
      ISNI: 0000000099381755
FAU - Li, Min-Hui
AU  - Li MH
AD  - 2Baotou Medical College, Baotou, Inner Mongolia, 014060 China. GRID: 
      grid.410594.d
FAU - Ren, Han-Kun
AU  - Ren HK
AD  - 1Beijing Key Laboratory of Plant Resources Research and Development, Beijing 
      Technology and Business University, Beijing, 100048 China. GRID: grid.411615.6. 
      ISNI: 0000000099381755
FAU - Shi, Yu-Jing
AU  - Shi YJ
AD  - 3Institute of Chinese Meteria Medica, China Academy of Chinese Medical Sciences, 
      Beijing, 100730 China. GRID: grid.410318.f. ISNI: 0000000406323409
FAU - Dong, Yin-Mao
AU  - Dong YM
AD  - 1Beijing Key Laboratory of Plant Resources Research and Development, Beijing 
      Technology and Business University, Beijing, 100048 China. GRID: grid.411615.6. 
      ISNI: 0000000099381755
LA  - eng
PT  - Journal Article
DEP - 20160430
PL  - Korea (South)
TA  - Food Sci Biotechnol
JT  - Food science and biotechnology
JID - 9816587
PMC - PMC6049181
OTO - NOTNLM
OT  - LC/MS/MS
OT  - anti-allergic activity
OT  - antihistamine
OT  - mast cell
OT  - mung bean sprouts
EDAT- 2016/04/30 00:00
MHDA- 2016/04/30 00:01
PMCR- 2017/04/30
CRDT- 2018/09/29 06:00
PHST- 2015/04/06 00:00 [received]
PHST- 2015/07/08 00:00 [revised]
PHST- 2015/12/16 00:00 [accepted]
PHST- 2018/09/29 06:00 [entrez]
PHST- 2016/04/30 00:00 [pubmed]
PHST- 2016/04/30 00:01 [medline]
PHST- 2017/04/30 00:00 [pmc-release]
AID - 77 [pii]
AID - 10.1007/s10068-016-0077-8 [doi]
PST - epublish
SO  - Food Sci Biotechnol. 2016 Apr 30;25(2):553-559. doi: 10.1007/s10068-016-0077-8. 
      eCollection 2016.