PMID- 30266204
OWN - NLM
STAT- MEDLINE
DCOM- 20190425
LR  - 20190425
IS  - 1768-3181 (Electronic)
IS  - 0003-3928 (Linking)
VI  - 67
IP  - 5
DP  - 2018 Nov
TI  - [Anemia in patients with acute coronary syndrome in the Vichy Hospital center].
PG  - 321-326
LID - S0003-3928(18)30126-4 [pii]
LID - 10.1016/j.ancard.2018.09.001 [doi]
AB  - INTRODUCTION: Objectives were to determine the clinical, epidemiological and 
      biological profile of the patients suffering from acute coronary syndrome and 
      presenting the anaemia, the determinants of variation of the haemoglobin rate, 
      and to estimate the impact of the anaemia on the prognosis of these patients. 
      PATIENTS AND METHODS: Retrospective and observational study conducted in the 
      cardiology department of Vichy Hospital in France. All patients with acute 
      coronary syndrome admitted from 31 of October 2015 to 30 of April 2016 were 
      selected. The patients were followed for 1 month. The anaemia was defined by: 
      less than 13g/dL in man and less than 12g/L in woman (WHO definition). Biological 
      markers were taken at the admission. Factors associated to the haemoglobin rate 
      were analysed by multivariate linear regression and those associated to the 
      mortality within 30 days were analysed by logistic regression. RESULTS: Among 251 
      included patients, there were 180 males and 71 females with the average age of 67 
      years. 94 patients had ST elevation myocardial infarction (STEMI), 116 had Non ST 
      myocardial infarction (NSTEMI) and 41 had unstable angina. Haemoglobin value was 
      known in 238 patient's, among whom 44.1% were anaemic (105/238). The anaemia was 
      more frequent in women. The tobacco was less frequent; High blood pressure, renal 
      failure, malnutrition, subclinical atherosclerosis, lower limb arteritis and the 
      inflammatory syndrome were more frequent in patients with anaemia. They presented 
      more complications. The age (P=0,003), the pulsed pressure (P=0,007), LVEF 
      (P=0,005), the albumin (P=0,010), Creatine kinase (CK) level (P=0,048) and of CRP 
      (P=0,011), were linear factors of variations of the haemoglobin rate 
      (R(2)=0,955). Ten patients died during the follow-up. The multivariate analysis 
      revealed the anaemia as independently associated with the mortality in 30 days 
      (Odds Ratio 3,69; P=0,02). CONCLUSION: Anaemia is frequent in patients with an 
      ACS, and it is associated with a particular clinical and biological profile. The 
      patients with anaemia have a mortality rate in 30 days higher than the patients 
      without anaemia.
CI  - Copyright (c) 2018 Elsevier Masson SAS. All rights reserved.
FAU - Ntima, G
AU  - Ntima G
AD  - Service de cardiologie, departement de medecine interne, cliniques universitaires 
      de Kinshasa, universite de Kinshasa, BP 834, 11 Kinshasa, Republique democratique 
      du Congo. Electronic address: coeurntima@gmail.com.
FAU - Bepouka, B
AU  - Bepouka B
AD  - Service de cardiologie, departement de medecine interne, cliniques universitaires 
      de Kinshasa, universite de Kinshasa, BP 834, 11 Kinshasa, Republique democratique 
      du Congo.
FAU - Tixier, V
AU  - Tixier V
AD  - Service de cardiologie, centre hospitalier de Vichy, 03200 Vichy, France.
FAU - Ferrier, N
AU  - Ferrier N
AD  - Service de cardiologie, centre hospitalier de Vichy, 03200 Vichy, France.
FAU - Marcaggi, X
AU  - Marcaggi X
AD  - Service de cardiologie, centre hospitalier de Vichy, 03200 Vichy, France.
LA  - fre
PT  - Journal Article
PT  - Observational Study
TT  - Anemie chez les patients avec syndrome coronarien aigu au centre hospitalier de 
      Vichy.
DEP - 20180925
PL  - France
TA  - Ann Cardiol Angeiol (Paris)
JT  - Annales de cardiologie et d'angeiologie
JID - 0142167
SB  - IM
MH  - Acute Coronary Syndrome/*epidemiology
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Anemia/*epidemiology
MH  - Arteritis/epidemiology
MH  - Atherosclerosis/epidemiology
MH  - Female
MH  - France/epidemiology
MH  - Humans
MH  - Hypertension/epidemiology
MH  - Male
MH  - Malnutrition/epidemiology
MH  - Middle Aged
MH  - Prognosis
MH  - Renal Insufficiency/epidemiology
MH  - Retrospective Studies
OTO - NOTNLM
OT  - Acute coronary syndrome
OT  - Anaemia
OT  - Anemie
OT  - Prognostic
OT  - Pronostic
OT  - Syndrome coronarien aigu
EDAT- 2018/09/30 06:00
MHDA- 2019/04/26 06:00
CRDT- 2018/09/30 06:00
PHST- 2018/09/04 00:00 [received]
PHST- 2018/09/06 00:00 [accepted]
PHST- 2018/09/30 06:00 [pubmed]
PHST- 2019/04/26 06:00 [medline]
PHST- 2018/09/30 06:00 [entrez]
AID - S0003-3928(18)30126-4 [pii]
AID - 10.1016/j.ancard.2018.09.001 [doi]
PST - ppublish
SO  - Ann Cardiol Angeiol (Paris). 2018 Nov;67(5):321-326. doi: 
      10.1016/j.ancard.2018.09.001. Epub 2018 Sep 25.