PMID- 30267296 OWN - NLM STAT- MEDLINE DCOM- 20190410 LR - 20190410 IS - 1573-2606 (Electronic) IS - 1389-9155 (Linking) VI - 19 IP - 2 DP - 2018 Jun TI - Is endoscopic ultrasonography more sensitive than magnetic resonance imaging in detecting and localizing pancreatic neuroendocrine tumors? PG - 133-137 LID - 10.1007/s11154-018-9464-1 [doi] AB - To compare endoscopic ultrasonography (EUS) and magnetic resonance imaging (MRI) in terms of their sensitivities to localize pancreatic neuroendocrine tumors (pNET) preoperatively. Systematic analysis of the literature; sensitivity of EUS and MRI in insulinomas and pancreaticoduodenal NETs in multiple endocrine neoplasia type 1 (MEN1) in series of at least 20 subjects referring to tumors confirmed by surgery and histopathology. Other imaging methods reported were also assessed. Eighteen publications on insulinomas (782 cases) could be analyzed, no study in MEN1 fulfilled the inclusion criteria and compared EUS to MRI. Data quality was moderate: all publications referred to case series. Mean correct detection / localization rates (sensitivity) were calculated: EUS 80%, MRI 66%, computed tomography 63%, angiography 52%, somatostatin receptor scintigraphy 42%, ultrasonography 23%; arterial calcium stimulation with hepatic venous sampling regionalized correctly in 80%. EUS seems to be more sensitive than MRI in localizing pancreatic neuroendocrine tumors. If a specialized endosonographist is available, EUS is the preferable imaging procedure. Otherwise, MRI is a suitable alternative. FAU - Kann, Peter Herbert AU - Kann PH AD - Centre for Endocrinology, Diabetology & Osteology, Endocrine Laboratory, Philipp's University and University Hospital Marburg, Marburg, Germany. kannp@med.uni-marburg.de. AD - German Centre for Endocrine Care, Frankfurt / Main, Germany. kannp@med.uni-marburg.de. LA - eng PT - Journal Article PT - Review PL - Germany TA - Rev Endocr Metab Disord JT - Reviews in endocrine & metabolic disorders JID - 100940588 SB - IM MH - Endosonography/*standards MH - Humans MH - Magnetic Resonance Imaging/*standards MH - Neuroendocrine Tumors/*diagnostic imaging MH - Pancreatic Neoplasms/*diagnostic imaging OTO - NOTNLM OT - EUS OT - Endoscopic ultrasonography OT - Insulinoma OT - MRI OT - Magnetic resonance imaging OT - NET OT - Neuroendocrine tumor EDAT- 2018/09/30 06:00 MHDA- 2019/04/11 06:00 CRDT- 2018/09/30 06:00 PHST- 2018/09/30 06:00 [pubmed] PHST- 2019/04/11 06:00 [medline] PHST- 2018/09/30 06:00 [entrez] AID - 10.1007/s11154-018-9464-1 [pii] AID - 10.1007/s11154-018-9464-1 [doi] PST - ppublish SO - Rev Endocr Metab Disord. 2018 Jun;19(2):133-137. doi: 10.1007/s11154-018-9464-1.