PMID- 30267370 OWN - NLM STAT- MEDLINE DCOM- 20190117 LR - 20211204 IS - 1993-0402 (Electronic) IS - 1672-0415 (Linking) VI - 24 IP - 10 DP - 2018 Oct TI - Coptidis Rhizoma-Contained Traditional Formulae for Insomnia: A Potential to Prevent Diabetes? PG - 785-788 LID - 10.1007/s11655-018-3012-4 [doi] AB - It has been well known that insomnia and sleep deprivation can lead to many metabolic diseases such as type 2 diabete mellitus (T2DM). Chinese medicine (CM) has been used to improve insomnia and showed many good therapeutic effects. Some Coptidis Rhizoma-contained traditional formulae have been found to exert obvious effects on insomnia, such as Jiaotai Pill (), Huanglian Ejiao Decoction (), Huanglian Wendan Decoction (), Niuhuang Qingxin Pill (), and Zhusha Anshen Pill (). Coptidis Rhizoma, a traditional herbal medicine which can purge Xin (Heart) fire, is the most important component of these formulas. Studies have found that these formulae could improve T2DM symptoms. We hypothesized that treating insomnia theoretically may help to prevent diabetes and organized many experimental studies in this review and concluded that Coptidis Rhizoma-contained traditional formulae for insomnia might be a potential to prevent diabetes. FAU - Huang, Wen-Ya AU - Huang WY AD - Institute of Integrative Traditional Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. FAU - Dong, Hui AU - Dong H AD - Institute of Integrative Traditional Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. tjhdonghui@163.com. LA - eng PT - Journal Article DEP - 20180929 PL - China TA - Chin J Integr Med JT - Chinese journal of integrative medicine JID - 101181180 RN - 0 (Drugs, Chinese Herbal) RN - CXS4LJR7EL (Coptidis rhizoma extract) SB - IM MH - Coptis chinensis MH - Diabetes Mellitus, Type 2/*etiology/*prevention & control MH - Drugs, Chinese Herbal/pharmacology/*therapeutic use MH - Dysbiosis/complications MH - Gastrointestinal Microbiome/drug effects MH - Humans MH - Sleep Initiation and Maintenance Disorders/*complications/*drug therapy OTO - NOTNLM OT - Chinese medicine OT - Coptidis Rhizoma OT - diabetes OT - herbal formulae OT - insomnia EDAT- 2018/09/30 06:00 MHDA- 2019/01/18 06:00 CRDT- 2018/09/30 06:00 PHST- 2018/04/08 00:00 [accepted] PHST- 2018/09/30 06:00 [entrez] PHST- 2018/09/30 06:00 [pubmed] PHST- 2019/01/18 06:00 [medline] AID - 10.1007/s11655-018-3012-4 [pii] AID - 10.1007/s11655-018-3012-4 [doi] PST - ppublish SO - Chin J Integr Med. 2018 Oct;24(10):785-788. doi: 10.1007/s11655-018-3012-4. Epub 2018 Sep 29.