PMID- 30271782
OWN - NLM
STAT- MEDLINE
DCOM- 20190107
LR  - 20220331
IS  - 2314-6141 (Electronic)
IS  - 2314-6133 (Print)
VI  - 2018
DP  - 2018
TI  - Relationship between Extension or Texture Features of Late Gadolinium Enhancement 
      and Ventricular Tachyarrhythmias in Hypertrophic Cardiomyopathy.
PG  - 4092469
LID - 10.1155/2018/4092469 [doi]
LID - 4092469
AB  - PURPOSE: To evaluate the relationship between extension or texture features of 
      late gadolinium enhancement (LGE) and ventricular tachyarrhythmias in 
      hypertrophic cardiomyopathy (HCM). MATERIALS AND METHODS: Twenty-three patients 
      with HCM were enrolled in this IRB-approved study. The extension of LGE was 
      determined based on the American Heart Association segments model. Texture 
      analysis was performed for 43 myocardial LGE using an open-access software 
      (MaZda, Technical University of Lodz, Institute of Electronics, Poland). The 
      relationship between the extension or texture features of LGE and ventricular 
      tachyarrhythmias was evaluated using unpaired test and receiver-operating 
      characteristic (ROC) analysis. RESULTS: Six of 23 patients had a history of 
      ventricular tachyarrhythmias, and 16 patients had LGE. All of the 6 patients with 
      the arrhythmias had more than 4 LGE segments and more LGE segments than those 
      without (p < 0.01). Among 4 texture features, entropy LL was the only 
      discriminator between the 2 patient groups (p < 0.01; threshold, 19624; area 
      under the curve [AUC], 0.72). An ROC analysis gave the number of segments showing 
      LGE a better result (AUC, 0.96) for identification of HCM patients with 
      ventricular tachyarrhythmias than the entropy LL of LGE. CONCLUSION: Patients 
      with HCM and a history of ventricular tachyarrhythmias had a wider extension of 
      LGE, and their entropy LL of LGE was significantly lower than those without. The 
      extension of LGE and texture analysis may provide information about LGE related 
      to ventricular tachyarrhythmias in HCM.
FAU - Amano, Yasuo
AU  - Amano Y
AUID- ORCID: 0000-0001-5058-4137
AD  - Department of Radiology, Nihon University Hospital, 1-6 Kanda-Surugadai, 
      Chiyoda-ku, Tokyo 101-8309, Japan.
FAU - Suzuki, Yasuyuki
AU  - Suzuki Y
AD  - Department of Cardiology, Nihon University Hospital, Tokyo, Japan.
FAU - Yanagisawa, Fumi
AU  - Yanagisawa F
AD  - Department of Radiology, Nihon University Hospital, 1-6 Kanda-Surugadai, 
      Chiyoda-ku, Tokyo 101-8309, Japan.
FAU - Omori, Yuko
AU  - Omori Y
AD  - Department of Radiology, Nihon University Hospital, 1-6 Kanda-Surugadai, 
      Chiyoda-ku, Tokyo 101-8309, Japan.
FAU - Matsumoto, Naoya
AU  - Matsumoto N
AD  - Department of Cardiology, Nihon University Hospital, Tokyo, Japan.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20180909
PL  - United States
TA  - Biomed Res Int
JT  - BioMed research international
JID - 101600173
RN  - 0 (Contrast Media)
RN  - AU0V1LM3JT (Gadolinium)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Cardiomyopathy, Hypertrophic/complications/*diagnostic imaging
MH  - Contrast Media
MH  - Cross-Sectional Studies
MH  - Female
MH  - Fibrosis
MH  - Gadolinium
MH  - Humans
MH  - *Magnetic Resonance Imaging, Cine
MH  - Male
MH  - Middle Aged
MH  - Myocardium
MH  - Retrospective Studies
MH  - Tachycardia/complications/*diagnostic imaging
PMC - PMC6151210
EDAT- 2018/10/03 06:00
MHDA- 2019/01/08 06:00
PMCR- 2018/09/09
CRDT- 2018/10/02 06:00
PHST- 2018/06/09 00:00 [received]
PHST- 2018/08/06 00:00 [accepted]
PHST- 2018/10/02 06:00 [entrez]
PHST- 2018/10/03 06:00 [pubmed]
PHST- 2019/01/08 06:00 [medline]
PHST- 2018/09/09 00:00 [pmc-release]
AID - 10.1155/2018/4092469 [doi]
PST - epublish
SO  - Biomed Res Int. 2018 Sep 9;2018:4092469. doi: 10.1155/2018/4092469. eCollection 
      2018.