PMID- 30271787
OWN - NLM
STAT- MEDLINE
DCOM- 20190107
LR  - 20190107
IS  - 2314-6141 (Electronic)
IS  - 2314-6133 (Print)
VI  - 2018
DP  - 2018
TI  - Association of H-Type Hypertension with Stroke Severity and Prognosis.
PG  - 8725908
LID - 10.1155/2018/8725908 [doi]
LID - 8725908
AB  - Background. The correlation between H-type hypertension and acute ischemic stroke 
      remains uncertain. Objective. The present study was designed to explore the 
      possible relationship between H-type hypertension and severity and prognosis of 
      acute ischemic stroke. Method. We included 372 patients with acute ischemic 
      stroke and divided them into four groups: H-type hypertension group, simple 
      hypertension group, simple hyperhomocysteinemia (HHcy) group, and the control 
      group. NIHSS score was measured at both admission and two weeks later. mRS score, 
      stroke recurrence, cardiovascular event, or all-cause mortality was recorded at 
      3-month and 1-year follow-up. Result. The results showed that the NIHSS score on 
      admission in the H-type hypertension group (6.32 +/- 5.91) was significantly higher 
      than that in the control group (3.97 +/- 3.59) (P < 0.05), while there was no 
      obvious association between H-type hypertension and NIHSS score after 2-week 
      treatment (P = 0.106). Endpoint events incidence in H-type hypertension group was 
      the highest; however, in the cox regression model of multiple factor analysis, 
      H-type hypertension was not an independent risk factor. Conclusion. H-type 
      hypertension may result in early functional deterioration and higher incidence 
      rate of endpoint events but not act as an independent risk factor.
FAU - Li, Tan
AU  - Li T
AD  - Department of Neurology, The First Affiliated Hospital of Soochow University, No. 
      899, Pinghai Road, Suzhou, Jiangsu 215006, China.
FAU - Zhu, Jiajia
AU  - Zhu J
AD  - Department of Neurology, The First Affiliated Hospital of Soochow University, No. 
      899, Pinghai Road, Suzhou, Jiangsu 215006, China.
FAU - Fang, Qi
AU  - Fang Q
AUID- ORCID: 0000-0002-9762-2687
AD  - Department of Neurology, The First Affiliated Hospital of Soochow University, No. 
      899, Pinghai Road, Suzhou, Jiangsu 215006, China.
FAU - Duan, Xiaoyu
AU  - Duan X
AD  - Department of Neurology, The First Affiliated Hospital of Soochow University, No. 
      899, Pinghai Road, Suzhou, Jiangsu 215006, China.
FAU - Zhang, Mingzhi
AU  - Zhang M
AD  - Department of Epidemiology & Biostatistics, Jiangsu Key Laboratory of Preventive 
      and Translational Medicine for Geriatric Diseases, School of Public Health, 
      Medical College of Soochow University, Suzhou, Jiangsu 215006, China.
FAU - Diao, Shanshan
AU  - Diao S
AD  - Department of Neurology, The First Affiliated Hospital of Soochow University, No. 
      899, Pinghai Road, Suzhou, Jiangsu 215006, China.
FAU - Zhou, Yun
AU  - Zhou Y
AD  - Department of Neurology, The First Affiliated Hospital of Soochow University, No. 
      899, Pinghai Road, Suzhou, Jiangsu 215006, China.
FAU - Yang, Si
AU  - Yang S
AD  - Department of Neurology, The First Affiliated Hospital of Soochow University, No. 
      899, Pinghai Road, Suzhou, Jiangsu 215006, China.
FAU - Kong, Yan
AU  - Kong Y
AUID- ORCID: 0000-0001-6599-2416
AD  - Department of Neurology, The First Affiliated Hospital of Soochow University, No. 
      899, Pinghai Road, Suzhou, Jiangsu 215006, China.
FAU - Cai, Xiuying
AU  - Cai X
AUID- ORCID: 0000-0002-3496-3281
AD  - Department of Neurology, The First Affiliated Hospital of Soochow University, No. 
      899, Pinghai Road, Suzhou, Jiangsu 215006, China.
LA  - eng
PT  - Journal Article
DEP - 20180909
PL  - United States
TA  - Biomed Res Int
JT  - BioMed research international
JID - 101600173
SB  - IM
MH  - Adult
MH  - Brain Ischemia/classification/*etiology
MH  - Female
MH  - Humans
MH  - Hypertension/*complications
MH  - Male
MH  - Prognosis
MH  - Risk Factors
MH  - Severity of Illness Index
MH  - Stroke/classification/*etiology
PMC - PMC6151242
EDAT- 2018/10/03 06:00
MHDA- 2019/01/08 06:00
PMCR- 2018/09/09
CRDT- 2018/10/02 06:00
PHST- 2018/04/19 00:00 [received]
PHST- 2018/07/24 00:00 [revised]
PHST- 2018/08/28 00:00 [accepted]
PHST- 2018/10/02 06:00 [entrez]
PHST- 2018/10/03 06:00 [pubmed]
PHST- 2019/01/08 06:00 [medline]
PHST- 2018/09/09 00:00 [pmc-release]
AID - 10.1155/2018/8725908 [doi]
PST - epublish
SO  - Biomed Res Int. 2018 Sep 9;2018:8725908. doi: 10.1155/2018/8725908. eCollection 
      2018.