PMID- 30279856
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 1878-5409 (Print)
IS  - 1878-5409 (Electronic)
IS  - 1878-5409 (Linking)
VI  - 17
IP  - 2
DP  - 2018 Feb
TI  - Narrowing of the QRS complex, elimination of late gadolinium enhancement and 
      remarkable reverse remodeling achieved by optimal medical treatment in 
      non-ischemic dilated cardiomyopathy.
PG  - 59-62
LID - 10.1016/j.jccase.2017.09.009 [doi]
AB  - A 67-year-old woman presented with exertional dyspnea. An electrocardiogram 
      showed complete left bundle branch block. Cardiac magnetic resonance imaging 
      revealed left ventricular (LV) dilatation with reduced ejection fraction, no 
      evidence of myocardial ischemia and late gadolinium enhancement (LGE) in the 
      inferior LV wall. She was diagnosed with decompensated heart failure (HF) 
      secondary to non-ischemic dilated cardiomyopathy. Narrowing of the QRS complex, 
      disappearance of LGE, and remarkable LV reverse remodeling along with improvement 
      in HF symptoms were achieved by combination therapy with angiotensin II receptor 
      blocker, beta-blocker, and mineralocorticoid receptor antagonist. This case 
      highlights the role of triple-blockade therapy in the treatment of HF. <Learning 
      objective: Complete left bundle branch block and late gadolinium enhancement 
      usually represent irreversible damage of myocardial tissue, and are related to 
      left ventricular (LV) remodeling. However, the clinical course of the present 
      case indicated that optimal medical therapies including sufficient amount of 
      renin-angiotensin-aldosterone inhibition and beta-adrenergic blockade can improve 
      ventricular conduction delay and myocardial tissue injury, and consequent 
      remarkable LV reverse remodeling.>.
FAU - Fukuoka, Shusuke
AU  - Fukuoka S
AD  - Department of Cardiology and Nephrology, Mie University Graduate School of 
      Medicine, Tsu, Japan.
AD  - Department of Cardiology, Matsusaka Chuo General Hospital, Matsusaka, Japan.
FAU - Dohi, Kaoru
AU  - Dohi K
AD  - Department of Cardiology and Nephrology, Mie University Graduate School of 
      Medicine, Tsu, Japan.
FAU - Ichikawa, Yasutaka
AU  - Ichikawa Y
AD  - Department of Radiology, Mie University Graduate School of Medicine, Tsu, Japan.
FAU - Tanigawa, Takashi
AU  - Tanigawa T
AD  - Department of Cardiology, Matsusaka Chuo General Hospital, Matsusaka, Japan.
FAU - Sakuma, Hajime
AU  - Sakuma H
AD  - Department of Radiology, Mie University Graduate School of Medicine, Tsu, Japan.
FAU - Ito, Masaaki
AU  - Ito M
AD  - Department of Cardiology and Nephrology, Mie University Graduate School of 
      Medicine, Tsu, Japan.
LA  - eng
PT  - Case Reports
DEP - 20171026
PL  - Japan
TA  - J Cardiol Cases
JT  - Journal of cardiology cases
JID - 101549579
PMC - PMC6149558
OTO - NOTNLM
OT  - Cardiac magnetic resonance imaging
OT  - Complete left bundle branch block
OT  - Non-ischemic dilated cardiomyopathy
OT  - Reverse remodeling
EDAT- 2018/10/04 06:00
MHDA- 2018/10/04 06:01
PMCR- 2017/10/26
CRDT- 2018/10/04 06:00
PHST- 2017/07/28 00:00 [received]
PHST- 2017/09/09 00:00 [revised]
PHST- 2017/09/20 00:00 [accepted]
PHST- 2018/10/04 06:00 [entrez]
PHST- 2018/10/04 06:00 [pubmed]
PHST- 2018/10/04 06:01 [medline]
PHST- 2017/10/26 00:00 [pmc-release]
AID - S1878-5409(17)30101-9 [pii]
AID - 10.1016/j.jccase.2017.09.009 [doi]
PST - epublish
SO  - J Cardiol Cases. 2017 Oct 26;17(2):59-62. doi: 10.1016/j.jccase.2017.09.009. 
      eCollection 2018 Feb.