PMID- 30289034 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20191120 IS - 1744-8417 (Electronic) IS - 1744-6651 (Linking) VI - 10 IP - 6 DP - 2015 Nov TI - Dulaglutide, a GLP-1 receptor agonist, for the treatment of type 2 diabetes. PG - 581-590 LID - 10.1586/17446651.2015.1098532 [doi] AB - The prevalence of diabetes continues to rise worldwide. Over the past five years, available treatment options have expanded to allow individualized management of patients with diabetes. The glucagon-like peptide-1 (GLP-1) receptor agonists have become an essential tool in the management of type 2 diabetes mellitus (T2DM). This class provides several advantages for glycemic control with minimal risk of hypoglycemia. Based on the most recent guidelines for T2DM, GLP-1 receptor agonists can be prescribed as monotherapy or in combination with oral antidiabetic agents or insulin for the management of T2DM. Dulaglutide has become the most recent and available GLP-1 receptor agonist on the market. Dulaglutide is a once-weekly GLP-1 receptor agonist that can be used as monotherapy or as a second-line agent for T2DM. This review article summarizes the efficacy, safety, and clinical attributes of dulaglutide among patients with T2DM. FAU - Clements, Jennifer AU - Clements J AD - a Department of Pharmacy Practice , Presbyterian College School of Pharmacy - Pharmacy Practice , Clinton , SC , USA. FAU - Moore, Katherine AU - Moore K AD - a Department of Pharmacy Practice , Presbyterian College School of Pharmacy - Pharmacy Practice , Clinton , SC , USA. FAU - Shealy, Kayce AU - Shealy K AD - a Department of Pharmacy Practice , Presbyterian College School of Pharmacy - Pharmacy Practice , Clinton , SC , USA. LA - eng PT - Journal Article DEP - 20151013 PL - England TA - Expert Rev Endocrinol Metab JT - Expert review of endocrinology & metabolism JID - 101278293 OTO - NOTNLM OT - diabetes mellitus OT - dulaglutide OT - glucagon-like peptide-1 receptor agonist OT - hyperglycemia OT - incretin mimetic OT - type 2 diabetes mellitus EDAT- 2015/11/01 00:00 MHDA- 2015/11/01 00:01 CRDT- 2018/10/06 06:00 PHST- 2018/10/06 06:00 [entrez] PHST- 2015/11/01 00:00 [pubmed] PHST- 2015/11/01 00:01 [medline] AID - 10.1586/17446651.2015.1098532 [doi] PST - ppublish SO - Expert Rev Endocrinol Metab. 2015 Nov;10(6):581-590. doi: 10.1586/17446651.2015.1098532. Epub 2015 Oct 13.