PMID- 30290275
OWN - NLM
STAT- MEDLINE
DCOM- 20191125
LR  - 20240320
IS  - 1559-2030 (Electronic)
IS  - 1551-7144 (Linking)
VI  - 74
DP  - 2018 Nov
TI  - A web-based program to improve treatment adherence in patients with type 2 
      diabetes: Development and study protocol.
PG  - 38-45
LID - S1551-7144(18)30333-1 [pii]
LID - 10.1016/j.cct.2018.10.002 [doi]
AB  - BACKGROUND: Many patients with type 2 diabetes mellitus (T2DM) sub-optimally 
      adhere to core treatment recommendations, such as healthy diets, sufficient 
      physical activity and pharmacological support. This paper describes the 
      development of the web-based computer-tailored program My Diabetes Profile (MDP), 
      incorporating identified success factors of web-based interventions, and the 
      protocol for testing the effectiveness of this program in a randomized 
      multicentre trial. METHODS: Formative research - including the input of a program 
      committee, qualitative and quantitative studies with patients and health 
      professionals and a literature search - yielded input for the development of the 
      MDP program. MDP provides video and text tailored advice, based on determinants 
      and salient beliefs derived from the I-Change Model, on decreasing unhealthy 
      snack intake, increasing physical activity, and improving adherence to both oral 
      blood glucose lowering drugs and self-administered insulin therapy. Patients with 
      T2DM recruited by practice nurses and diabetes nurses across the Netherlands fill 
      in online questionnaires at baseline and six-months follow-up. Participants are 
      randomized on patient level to the intervention group (access to the MDP program) 
      or control group (receiving care as usual). DISCUSSION: The formative research 
      using co-creation principles proved essential in the development of the MDP 
      program and involved various disciplines in T2DM management including target 
      group representatives. Co-creation revealed clearly that patients needed short 
      and attractive messages. Consequently, a mix of video and short text messages 
      were chosen for the ultimate program format. Pilot testing was useful to further 
      shape the program to needs of patients and professionals. TRIAL REGISTRATION: 
      Dutch Trial Register NTR6840; Archived program website: 
      http://www.webcitation.org/6xXz01S7X.
CI  - Copyright (c) 2018 Elsevier Inc. All rights reserved.
FAU - Vluggen, S
AU  - Vluggen S
AD  - Department of Health Promotion, School CAPHRI, Maastricht University, Maastricht, 
      the Netherlands. Electronic address: stan.vluggen@maastrichtuniversity.nl.
FAU - Hoving, C
AU  - Hoving C
AD  - Department of Health Promotion, School CAPHRI, Maastricht University, Maastricht, 
      the Netherlands. Electronic address: c.hoving@maastrichtuniversity.nl.
FAU - Schaper, N C
AU  - Schaper NC
AD  - Department of Endocrinology and Internal Medicine, School CAPHRI, Maastricht 
      University Medical Centre (MUMC+), Maastricht, the Netherlands. Electronic 
      address: n.schaper@mumc.nl.
FAU - de Vries, H
AU  - de Vries H
AD  - Department of Health Promotion, School CAPHRI, Maastricht University, Maastricht, 
      the Netherlands. Electronic address: hein.devries@maastrichtuniversity.nl.
LA  - eng
SI  - NTR/NTR6840
PT  - Clinical Trial Protocol
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20181002
PL  - United States
TA  - Contemp Clin Trials
JT  - Contemporary clinical trials
JID - 101242342
RN  - 0 (Hypoglycemic Agents)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Diabetes Mellitus, Type 2/*therapy
MH  - *Diet, Healthy
MH  - *Exercise
MH  - Humans
MH  - Hypoglycemic Agents/*therapeutic use
MH  - *Internet
MH  - *Medication Adherence
MH  - Middle Aged
MH  - Netherlands
MH  - Program Development
MH  - Treatment Adherence and Compliance
MH  - Randomized Controlled Trials as Topic
OTO - NOTNLM
OT  - Computer-tailoring
OT  - Effect evaluation
OT  - Randomized controlled trial
OT  - Study protocol
OT  - Treatment adherence
OT  - Type 2 diabetes
EDAT- 2018/10/06 06:00
MHDA- 2019/11/26 06:00
CRDT- 2018/10/06 06:00
PHST- 2018/05/31 00:00 [received]
PHST- 2018/09/28 00:00 [revised]
PHST- 2018/10/01 00:00 [accepted]
PHST- 2018/10/06 06:00 [pubmed]
PHST- 2019/11/26 06:00 [medline]
PHST- 2018/10/06 06:00 [entrez]
AID - S1551-7144(18)30333-1 [pii]
AID - 10.1016/j.cct.2018.10.002 [doi]
PST - ppublish
SO  - Contemp Clin Trials. 2018 Nov;74:38-45. doi: 10.1016/j.cct.2018.10.002. Epub 2018 
      Oct 2.