PMID- 30293732 OWN - NLM STAT- MEDLINE DCOM- 20190409 LR - 20190409 IS - 1535-7732 (Electronic) IS - 1051-0443 (Linking) VI - 29 IP - 11 DP - 2018 Nov TI - Single-Center Retrospective Review of Radiofrequency Wire Recanalization of Refractory Central Venous Occlusions. PG - 1571-1577 LID - S1051-0443(18)31291-0 [pii] LID - 10.1016/j.jvir.2018.06.017 [doi] AB - PURPOSE: To retrospectively review the effectiveness and safety of radiofrequency (RF) wire recanalization of refractory central venous occlusions (CVOs) and compare recurrent and nonrecurrent CVOs in terms of patient and occlusion characteristics. MATERIALS AND METHODS: Twenty CVOs were treated in 18 patients (age 40 y +/- 13; 9 women) with 11 superior vena cava (SVC) or brachiocephalic vein occlusions (ie, supradiaphragmatic) and 9 inferior vena cava or iliac vein occlusions (ie, infradiaphragmatic). Indications included pain, edema, ulceration, and/or dialysis arteriovenous fistula dysfunction peripheral to the CVO(s). All patients had multiple venous thrombotic risk factors, including mechanical venous compression, endothelial injury, and/or coagulopathies. CVO traversal was first attempted with standard and advanced techniques before RF wire recanalization and followed up with computed tomographic venography and clinic visits approximately 1, 3, 6, and 12 months after treatment. RESULTS: Sixteen CVOs (80%) were successfully transversed and associated with symptom relief. One major complication occurred involving SVC perforation into the pericardial space. Primary CVO patency rate was 56% at a median follow-up of 14.1 months (interquartile range [IQR], 9.2-20.0 mo). Recurrent CVOs tended to be infradiaphragmatic (71% vs 12% for supradiaphragmatic; P = .02), longer (12.9 cm +/- 10.0 vs 2.3 cm +/- 1.3; P < .01), and associated with implanted venous stents, filters, or cardiac pacer/defibrillator leads (86% vs 22%; P = .01). Median time to restenosis/occlusion was 1.5 months (IQR, 1.1-6.1 mo). CONCLUSIONS: RF wire recanalization is a relatively effective and safe option for refractory CVOs. Patients with longer, infradiaphragmatic CVOs associated with indwelling devices may require closer follow-up for CVO recurrence. CI - Copyright (c) 2018 SIR. Published by Elsevier Inc. All rights reserved. FAU - Keller, Eric J AU - Keller EJ AD - Division of Interventional Radiology, Northwestern University, 737 N. Michigan Ave., Suite 1600, Chicago, IL 60611. Electronic address: ejkeller607@gmail.com. FAU - Gupta, Suraj A AU - Gupta SA AD - Division of Interventional Radiology, Northwestern University, 737 N. Michigan Ave., Suite 1600, Chicago, IL 60611. FAU - Bondarev, Sergey AU - Bondarev S AD - Division of Interventional Radiology, Northwestern University, 737 N. Michigan Ave., Suite 1600, Chicago, IL 60611. FAU - Sato, Kent T AU - Sato KT AD - Division of Interventional Radiology, Northwestern University, 737 N. Michigan Ave., Suite 1600, Chicago, IL 60611. FAU - Vogelzang, Robert L AU - Vogelzang RL AD - Division of Interventional Radiology, Northwestern University, 737 N. Michigan Ave., Suite 1600, Chicago, IL 60611. FAU - Resnick, Scott A AU - Resnick SA AD - Division of Interventional Radiology, Northwestern University, 737 N. Michigan Ave., Suite 1600, Chicago, IL 60611. LA - eng PT - Comparative Study PT - Journal Article DEP - 20181004 PL - United States TA - J Vasc Interv Radiol JT - Journal of vascular and interventional radiology : JVIR JID - 9203369 SB - IM MH - Adult MH - Catheter Ablation/adverse effects/*instrumentation MH - Chicago MH - Computed Tomography Angiography MH - Constriction, Pathologic MH - Equipment Design MH - Female MH - Humans MH - Male MH - Middle Aged MH - Phlebography/methods MH - Recurrence MH - Retrospective Studies MH - Risk Factors MH - Time Factors MH - Treatment Outcome MH - *Vascular Access Devices MH - Vascular Diseases/diagnostic imaging/physiopathology/*surgery MH - Vascular Patency MH - Veins/diagnostic imaging/physiopathology/*surgery MH - Young Adult EDAT- 2018/10/09 06:00 MHDA- 2019/04/10 06:00 CRDT- 2018/10/09 06:00 PHST- 2017/12/14 00:00 [received] PHST- 2018/05/29 00:00 [revised] PHST- 2018/06/25 00:00 [accepted] PHST- 2018/10/09 06:00 [pubmed] PHST- 2019/04/10 06:00 [medline] PHST- 2018/10/09 06:00 [entrez] AID - S1051-0443(18)31291-0 [pii] AID - 10.1016/j.jvir.2018.06.017 [doi] PST - ppublish SO - J Vasc Interv Radiol. 2018 Nov;29(11):1571-1577. doi: 10.1016/j.jvir.2018.06.017. Epub 2018 Oct 4.