PMID- 30293924
OWN - NLM
STAT- MEDLINE
DCOM- 20200224
LR  - 20200224
IS  - 1444-2892 (Electronic)
IS  - 1443-9506 (Linking)
VI  - 28
IP  - 11
DP  - 2019 Nov
TI  - The C-Reactive Protein to Albumin Ratio Predicts Acute Kidney Injury in Patients 
      With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous 
      Coronary Intervention.
PG  - 1638-1645
LID - S1443-9506(18)31863-8 [pii]
LID - 10.1016/j.hlc.2018.08.009 [doi]
AB  - BACKGROUND: The relationship between acute kidney injury (AKI) and C-reactive 
      protein (CRP) and albumin has been previously demonstrated in patients with ST 
      elevation myocardial infarction (STEMI) treated with primary percutaneous 
      coronary intervention (pPCI). However, to our knowledge, CRP to albumin ratio 
      (CAR), a newly introduced inflammation-based risk score, has not yet been 
      studied. In this study, we aimed to investigate the possible relationship between 
      the CAR and AKI. METHOD: A total of 815 consecutive STEMI patients treated with 
      pPCI were reviewed. RESULTS: One hundred ten 110 (13.5%) patients developed AKI 
      in the study population. The subjects were divided into two groups according to 
      AKI development. The in-hospital mortality rate was higher in patients with AKI 
      than those without AKI (15.5% vs. 1.3%; p<0.001). The patients with AKI had 
      significantly higher mean value of CRP and CAR (0.29 [0.16-0.50] vs. 0.55 
      [0.37-1.05]; p<0.001) and lower mean levels of albumin than those without AKI. 
      Age, diabetes mellitus, haematocrit, left ventricular ejection fraction, 
      hypotension, and CAR (Odds ratio [OR]2.307, 95% confidence interval [CI] 
      1.397-3.809, p=0.001) were independent predictors of AKI. CONCLUSION: The CAR may 
      be a useful inflammation-based risk score to predict AKI development in STEMI 
      patients treated with pPCI.
CI  - Copyright (c) 2018 Australian and New Zealand Society of Cardiac and Thoracic 
      Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). 
      Published by Elsevier B.V. All rights reserved.
FAU - Karabag, Yavuz
AU  - Karabag Y
AD  - M.D. Kafkas University Medical Faculty, Department of Cardiology, Kars, Turkey. 
      Electronic address: yavuz_karabag@hotmail.com.
FAU - Cagdas, Metin
AU  - Cagdas M
AD  - M.D. Kafkas University Medical Faculty, Department of Cardiology, Kars, Turkey.
FAU - Rencuzogullari, Ibrahim
AU  - Rencuzogullari I
AD  - M.D. Kafkas University Medical Faculty, Department of Cardiology, Kars, Turkey.
FAU - Karakoyun, Suleyman
AU  - Karakoyun S
AD  - M.D. Kafkas University Medical Faculty, Department of Cardiology, Kars, Turkey.
FAU - Artac, Inanc
AU  - Artac I
AD  - M.D. Kafkas University Medical Faculty, Department of Cardiology, Kars, Turkey.
FAU - Ilis, Dogan
AU  - Ilis D
AD  - M.D. Kafkas University Medical Faculty, Department of Cardiology, Kars, Turkey.
FAU - Yesin, Mahmut
AU  - Yesin M
AD  - M.D. Kars Harakani State Hospital, Department of Cardiology, Kars, Turkey.
FAU - Ciftci, Handan
AU  - Ciftci H
AD  - M.D. Kafkas University Medical Faculty, Department of Emergency Medicine, Kars, 
      Turkey.
FAU - Erdogdu, Halil Ibrahim
AU  - Erdogdu HI
AD  - M.D. Kafkas University Medical Faculty, Department of Emergency Medicine, Kars, 
      Turkey.
FAU - Tanboga, Ibrahim Halil
AU  - Tanboga IH
AD  - M.D. Ataturk University Medical Faculty, Department of Cardiology, Erzurum, 
      Turkey.
LA  - eng
PT  - Journal Article
DEP - 20180909
PL  - Australia
TA  - Heart Lung Circ
JT  - Heart, lung & circulation
JID - 100963739
RN  - 0 (Biomarkers)
RN  - 0 (Serum Albumin)
RN  - 9007-41-4 (C-Reactive Protein)
SB  - IM
MH  - Acute Kidney Injury/*blood/epidemiology/etiology
MH  - Biomarkers/blood
MH  - C-Reactive Protein/*metabolism
MH  - Electrocardiography
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Middle Aged
MH  - *Percutaneous Coronary Intervention
MH  - Predictive Value of Tests
MH  - Preoperative Period
MH  - Prognosis
MH  - Retrospective Studies
MH  - ST Elevation Myocardial Infarction/*blood/complications/surgery
MH  - Serum Albumin/*metabolism
MH  - Turkey/epidemiology
OTO - NOTNLM
OT  - Acute kidney injury
OT  - Albumin
OT  - C-Reactive protein
OT  - C-Reactive protein to albumin ratio
OT  - Primary percutaneous coronary intervention
OT  - ST elevation myocardial infarction
EDAT- 2018/10/09 06:00
MHDA- 2020/02/25 06:00
CRDT- 2018/10/09 06:00
PHST- 2018/01/10 00:00 [received]
PHST- 2018/05/21 00:00 [revised]
PHST- 2018/08/17 00:00 [accepted]
PHST- 2018/10/09 06:00 [pubmed]
PHST- 2020/02/25 06:00 [medline]
PHST- 2018/10/09 06:00 [entrez]
AID - S1443-9506(18)31863-8 [pii]
AID - 10.1016/j.hlc.2018.08.009 [doi]
PST - ppublish
SO  - Heart Lung Circ. 2019 Nov;28(11):1638-1645. doi: 10.1016/j.hlc.2018.08.009. Epub 
      2018 Sep 9.