PMID- 30295539
OWN - NLM
STAT- MEDLINE
DCOM- 20181015
LR  - 20181015
IS  - 2049-4408 (Electronic)
IS  - 2049-4394 (Linking)
VI  - 100-B
IP  - 10
DP  - 2018 Oct
TI  - A randomized prospective study comparing mobile-bearing against fixed-bearing PFC 
      Sigma cruciate-retaining total knee arthroplasties with ten-year minimum 
      follow-up.
PG  - 1336-1344
LID - 10.1302/0301-620X.100B10.BJJ-2017-1450.R1 [doi]
AB  - AIMS: This study compares the PFC total knee arthroplasty (TKA) system in a 
      prospective randomized control trial (RCT) of the mobile-bearing 
      rotating-platform (RP) TKA against the fixed-bearing (FB) TKA. This is the 
      largest RCT with the longest follow-up where cruciate-retaining PFC total knee 
      arthroplasties are compared in a non-bilateral TKA study. PATIENTS AND METHODS: A 
      total of 167 patients (190 knees with 23 bilateral cases), were recruited 
      prospectively and randomly assigned, with 91 knees receiving the RP and 99 knees 
      receiving FB. The mean age was 65.5 years (48 to 82), the mean body mass index 
      (BMI) was 29.7 kg/m(2) (20 to 52) and 73 patients were female. The Knee Society 
      Score (KSS), Knee Society Functional Score (KSFS), Oxford Knee Score (OKS), 
      Western Ontario and McMaster Universities Arthritis Index (WOMAC), and 12-Item 
      Short-Form Health Survey Physical and Mental Component Scores (SF-12 PCS, SF-12 
      MCS) were gathered and recorded preoperatively, at five-years' follow-up, and at 
      ten years' follow-up. Additionally, Knee Injury and Osteoarthritis Outcome Scores 
      (KOOS) were collected at five- and ten-year follow-ups. The prevalence of 
      radiolucent lines (RL) on radiographs and implant survival were recorded at five- 
      and ten-year follow-ups. RESULTS: At the ten-year follow-up, the RP group (n = 
      39) had a statistically significant superior score in the OKS (p = 0.001), WOMAC 
      (p = 0.023), SF-12 PCS (p = 0.019), KOOS Activities of Daily Living (ADL) (p = 
      0.010), and KOOS Sport and Recreation (Sport/Rec) (p = 0.006) compared with the 
      FB group (n = 46). The OKS, SF-12 PCS, and KOOS Sport/Rec at ten years had mean 
      scores above the minimal clinically important difference (MCID) threshold. There 
      was no significant difference in prevalence of radiolucency between groups at 
      five-years' follow-up (p = 0.449), nor at ten-years' follow-up (p = 0.08). 
      Implant survival rate at 14 years postoperative was 95.2 (95% CI 90.7 to 99.8) 
      and 94.7 (95% CI 86.8 to 100.0) for the RP and FB TKAs, respectively. CONCLUSION: 
      At ten-year follow-up, the mobile-bearing knee joint arthroplasty had 
      statistically and clinically relevant superior OKS, SF-12 PCS, and KOOS 
      (Sport/Rec) than the fixed-bearing platform. No difference was seen in prevalence 
      of radiolucent lines. There was a greater than 94% implant survival rate for both 
      cohorts at 14 years. Cite this article: Bone Joint J 2018;100-B:1336-44.
FAU - Powell, A J
AU  - Powell AJ
AD  - Department of Trauma and Orthopaedic Surgery, Middlemore and Ascot Hospitals, 
      Auckland, New Zealand.
FAU - Crua, E
AU  - Crua E
AD  - Department of Trauma and Orthopaedic Surgery, Ascot Hospital, Auckland, New 
      Zealand.
FAU - Chong, B C
AU  - Chong BC
AD  - University of Auckland, School of Medicine, Auckland, New Zealand.
FAU - Gordon, R
AU  - Gordon R
AD  - Department of Trauma and Orthopaedic Surgery, Middlemore and Ascot Hospitals, 
      Auckland, New Zealand.
FAU - McAuslan, A
AU  - McAuslan A
AD  - Department of Trauma and Orthopaedic Surgery, Middlemore and Ascot Hospitals, 
      Auckland, New Zealand.
FAU - Pitto, R P
AU  - Pitto RP
AD  - Department of Trauma and Orthopaedic Surgery, Middlemore and Ascot Hospitals, 
      Auckland, New Zealand.
FAU - Clatworthy, M G
AU  - Clatworthy MG
AD  - Department of Trauma and Orthopaedic Surgery, Middlemore and Ascot Hospitals, 
      Auckland, New Zealand.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - England
TA  - Bone Joint J
JT  - The bone & joint journal
JID - 101599229
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Arthroplasty, Replacement, Knee/*instrumentation
MH  - Female
MH  - Follow-Up Studies
MH  - Health Status Indicators
MH  - Humans
MH  - *Knee Prosthesis
MH  - Male
MH  - Middle Aged
MH  - Osteoarthritis, Knee/*surgery
MH  - Prospective Studies
MH  - Single-Blind Method
MH  - Treatment Outcome
EDAT- 2018/10/09 06:00
MHDA- 2018/10/16 06:00
CRDT- 2018/10/09 06:00
PHST- 2018/10/09 06:00 [entrez]
PHST- 2018/10/09 06:00 [pubmed]
PHST- 2018/10/16 06:00 [medline]
AID - 10.1302/0301-620X.100B10.BJJ-2017-1450.R1 [doi]
PST - ppublish
SO  - Bone Joint J. 2018 Oct;100-B(10):1336-1344. doi: 
      10.1302/0301-620X.100B10.BJJ-2017-1450.R1.