PMID- 30295715
OWN - NLM
STAT- MEDLINE
DCOM- 20191125
LR  - 20201230
IS  - 1442-2050 (Electronic)
IS  - 1120-8694 (Print)
IS  - 1120-8694 (Linking)
VI  - 32
IP  - 4
DP  - 2019 Apr 1
TI  - Food impaction: etiology over 35 years and association with eosinophilic 
      esophagitis.
LID - 10.1093/dote/doy093 [doi]
LID - doy093
AB  - With the emergence of eosinophilic esophagitis (EoE) as a common cause of food 
      impaction (FI) and a presumed increase in incidence of EoE in the population, the 
      effect on the incidence of FI has not been well described. The aim of this study 
      is to describe the incidence of FI and endoscopic findings in these patients and 
      the association with EoE. A population-based retrospective chart review of the 
      Rochester Epidemiology Project database was performed to identify all patients 
      within Olmsted County that presented with FI from 1976 to 2012. A review of all 
      endoscopic findings, biopsy results, and demographic data was performed. 497 
      patients were identified with FI from 1976 to 2012. The overall incidence of FI 
      has changed from 1976 to 2012 (Fig. 1) (P < 0.001). The peak incidence of 17.12 
      per 100,000 people occurred in the time period 1995 to 2000. Both the incidence 
      of comorbid gastroesophageal reflux disease (GERD) and proton pump inhibitor 
      (PPI) use increased over the time period of the study (P < 0.001 for both). Of 
      these patients, 188 (46.7%) had no abnormalities on their endoscopy. The most 
      common endoscopic finding was stricture in 71 (17.6%) patients followed closely 
      by Schatzki's ring in 68 (16.9%) patients. 139 patients had biopsies performed 
      within 2 years of FI and 50 (36.0%) of those were diagnosed with EoE. We present 
      for the first time the changing incidence of FI over the last 35 years in a 
      population-based setting. We also demonstrate the rise of EoE as an important 
      clinical consideration in patients with FI.
CI  - (c) The Author(s) 2018. Published by Oxford University Press on behalf of 
      International Society for Diseases of the Esophagus.
FAU - Lenz, C J
AU  - Lenz CJ
AD  - Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
FAU - Leggett, C
AU  - Leggett C
AD  - Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, 
      USA.
FAU - Katzka, D A
AU  - Katzka DA
AD  - Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
AD  - Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, 
      USA.
FAU - Larson, J J
AU  - Larson JJ
AD  - Department of Biostatistics and Informatics, Mayo Clinic, Rochester, Minnesota, 
      USA.
FAU - Enders, F T
AU  - Enders FT
AD  - Department of Biostatistics and Informatics, Mayo Clinic, Rochester, Minnesota, 
      USA.
FAU - Alexander, J A
AU  - Alexander JA
AD  - Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, 
      USA.
LA  - eng
GR  - R01 AG034676/AG/NIA NIH HHS/United States
PT  - Evaluation Study
PT  - Journal Article
PL  - United States
TA  - Dis Esophagus
JT  - Diseases of the esophagus : official journal of the International Society for 
      Diseases of the Esophagus
JID - 8809160
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
EIN - Dis Esophagus. 2019 Apr 1;32(4):. PMID: 30847465
MH  - Deglutition Disorders/epidemiology/*etiology
MH  - Eosinophilic Esophagitis/*complications/drug therapy/epidemiology
MH  - Esophageal Diseases/epidemiology/*etiology
MH  - Female
MH  - Food/*adverse effects
MH  - Gastroesophageal Reflux/epidemiology/etiology
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Middle Aged
MH  - New York/epidemiology
MH  - Proton Pump Inhibitors/therapeutic use
MH  - Retrospective Studies
PMC - PMC6437263
OTO - NOTNLM
OT  - dysphagia
OT  - eosinophilic esophagitis
OT  - esophagus
OT  - food impaction
EDAT- 2018/10/09 06:00
MHDA- 2019/11/26 06:00
PMCR- 2019/10/08
CRDT- 2018/10/09 06:00
PHST- 2018/08/28 00:00 [accepted]
PHST- 2018/06/11 00:00 [received]
PHST- 2018/08/23 00:00 [revised]
PHST- 2018/10/09 06:00 [pubmed]
PHST- 2019/11/26 06:00 [medline]
PHST- 2018/10/09 06:00 [entrez]
PHST- 2019/10/08 00:00 [pmc-release]
AID - 5123412 [pii]
AID - doy093 [pii]
AID - 10.1093/dote/doy093 [doi]
PST - ppublish
SO  - Dis Esophagus. 2019 Apr 1;32(4):doy093. doi: 10.1093/dote/doy093.