PMID- 30303873
OWN - NLM
STAT- MEDLINE
DCOM- 20190826
LR  - 20190826
IS  - 1528-1140 (Electronic)
IS  - 0003-4932 (Linking)
VI  - 268
IP  - 5
DP  - 2018 Nov
TI  - Single-incision Laparoscopy Versus Multiport Laparoscopy for Colonic Surgery: A 
      Multicenter, Double-blinded, Randomized Controlled Trial.
PG  - 740-746
LID - 10.1097/SLA.0000000000002836 [doi]
AB  - OBJECTIVE: To compare outcome of single-port laparoscopy (SPL) and multiport 
      laparoscopy (MPL) laparoscopy for colonic surgery. SUMMARY OF BACKGROUND DATA: 
      Benefits of SPL over MPL are yet to be demonstrated in large randomized trials. 
      METHODS: In this prospective, double-blinded, superiority trial, patients 
      undergoing laparoscopic colonic resection for benign or malignant disease were 
      randomly assigned to SPL or MPL (NCT01959087). Primary outcome was length of 
      theoretical hospital stay (LHS). RESULTS: One hundred twenty-eight patients were 
      randomized and 125 analyzed: 62 SPL and 63 MPL, including 91 right (SPL: n = 44, 
      71%; MPL: n = 47, 75%) and 34 left (SPL: n = 18, 29%; MPL: n = 16, 25%) 
      colectomies, performed for Crohn disease (n = 53, 42%), cancer (n = 36, 29%), 
      diverticulitis (n = 21, 17%), or benign neoplasia (n = 15, 12%). Additional port 
      insertion was required in 5 (8%) SPL patients and conversion to laparotomy 
      occurred in 7 patients (SPL: n = 3, 5%; MPL: n = 4, 7%; P = 1.000). Total length 
      of skin incision was significantly shorter in the SPL group [SPL: 56 +/- 41 (range, 
      30-300) mm; MPL: 87 +/- 40 (50-250) mm; P < 0.001]. Procedure duration, 
      intraoperative complication rate, postoperative 30-day morbidity, postoperative 
      pain, and time to first bowel movement were similar between the groups, leading 
      to similar theoretical LHS (SPL: 6 +/- 3 days; MPL: 6 +/- 2; P = 0.298). At 6 months, 
      quality of life was similar between groups, but patients from the SPL group were 
      significantly more satisfied with their scar aspect than patients from the MPL 
      group (P = 0.003). CONCLUSION: SPL colectomy does not confer any additional 
      benefit other than cosmetic result, as compared to MPL.
FAU - Maggiori, Leon
AU  - Maggiori L
AD  - Colorectal Surgery Department, Hopital Beaujon, Assistance Publique-Hopitaux de 
      Paris, University Paris VII, Clichy, France.
FAU - Tuech, Jean Jacques
AU  - Tuech JJ
AD  - Department of Digestive Surgery, CHU Rouen, Rouen University, Rouen, France.
FAU - Cotte, Eddy
AU  - Cotte E
AD  - Department of Digestive Surgery, CHU Lyon-Sud, Lyon University, Lyon, France.
FAU - Lelong, Bernard
AU  - Lelong B
AD  - Department of Oncological Surgery, Institut Paoli-Calmettes, Marseille, France.
FAU - Denost, Quentin
AU  - Denost Q
AD  - Colorectal unit, Hopital Haut Leveque, CHU Bordeaux, University of Bordeaux, 
      Bordeaux, France.
FAU - Karoui, Mehdi
AU  - Karoui M
AD  - Department of Digestive and Hepato-Pancreato-Biliary Surgery, Hopital 
      Pitie-Salpetriere, Assistance Publique-Hopitaux de Paris, Pierre & Marie Curie 
      University (Paris VI), Paris, France.
FAU - Vicaut, Eric
AU  - Vicaut E
AD  - Department of Clinical Research, Hopital Lariboisiere, Assistance 
      publique-Hopitaux de Paris, University Paris VII, Paris, France.
FAU - Panis, Yves
AU  - Panis Y
AD  - Colorectal Surgery Department, Hopital Beaujon, Assistance Publique-Hopitaux de 
      Paris, University Paris VII, Clichy, France.
LA  - eng
SI  - ClinicalTrials.gov/NCT01959087
PT  - Journal Article
PT  - Multicenter Study
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Ann Surg
JT  - Annals of surgery
JID - 0372354
CIN - Ann Surg. 2019 Dec;270(6):e106-e107. PMID: 31058701
CIN - Ann Surg. 2019 Dec;270(6):e107-e108. PMID: 31425285
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Colectomy/*methods
MH  - Colonic Diseases/*surgery
MH  - Double-Blind Method
MH  - Esthetics
MH  - Female
MH  - France
MH  - Humans
MH  - Intraoperative Complications/classification
MH  - Laparoscopy/*methods
MH  - Length of Stay/statistics & numerical data
MH  - Male
MH  - Middle Aged
MH  - Operative Time
MH  - Pain, Postoperative/epidemiology
MH  - Patient Satisfaction
MH  - Postoperative Complications/classification
MH  - Prospective Studies
MH  - Quality of Life
MH  - Treatment Outcome
EDAT- 2018/10/12 06:00
MHDA- 2019/08/27 06:00
CRDT- 2018/10/11 06:00
PHST- 2018/10/11 06:00 [entrez]
PHST- 2018/10/12 06:00 [pubmed]
PHST- 2019/08/27 06:00 [medline]
AID - 00000658-201811000-00006 [pii]
AID - 10.1097/SLA.0000000000002836 [doi]
PST - ppublish
SO  - Ann Surg. 2018 Nov;268(5):740-746. doi: 10.1097/SLA.0000000000002836.