PMID- 30305588
OWN - NLM
STAT- MEDLINE
DCOM- 20181212
LR  - 20181212
IS  - 1349-3299 (Electronic)
IS  - 1349-2365 (Linking)
VI  - 59
IP  - 6
DP  - 2018 Nov 28
TI  - Determinants of Slow Flow in Percutaneous Coronary Intervention to the Culprit 
      Lesion of Non-ST Elevation Myocardial Infarction.
PG  - 1237-1245
LID - 10.1536/ihj.18-050 [doi]
AB  - Slow flow is a serious complication in percutaneous coronary intervention (PCI) 
      and is associated with poor clinical outcomes. Our previous study revealed that 
      the ratio of stent diameter to vessel diameter was the determinant of slow flow 
      in intravascular ultrasound (IVUS)-guided PCI to the culprit lesion of ST 
      elevation myocardial infarction (STEMI). The purpose of this study was to verify 
      whether the ratio of stent diameter to vessel diameter is the determinant of slow 
      flow in IVUS-guided PCI to the culprit lesion of non-STEMI (NSTEMI). We included 
      150 NSTEMI patients and divided into the slow flow group (n = 17) and the 
      non-slow flow group (n = 133). The ratio of stent diameter to vessel diameter was 
      significantly larger in the slow flow group (0.77 +/- 0.11) than the non-slow flow 
      group (0.71 +/- 0.11) (P = 0.03). Multivariate logistic regression analysis 
      revealed that the ratio of stent diameter to vessel diameter (per 0.1 increase: 
      OR 2.06, 95% CI 1.23-3.46, P = 0.006) was the determinant of slow flow after 
      controlling covariates. In conclusion, the ratio of stent diameter to vessel 
      diameter was the determinant of slow flow in IVUS-guided PCI to the culprit 
      lesion of NSTEMI. Unlike other parameters, the ratio of stent diameter to vessel 
      diameter is the modifiable parameters. We may consider the modest stent expansion 
      strategy rather than the aggressive stent expansion strategy in IVUS-guided PCI 
      to the culprit lesion of NSTEMI.
FAU - Watanabe, Yusuke
AU  - Watanabe Y
AD  - Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical 
      University.
FAU - Sakakura, Kenichi
AU  - Sakakura K
AD  - Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical 
      University.
FAU - Taniguchi, Yousuke
AU  - Taniguchi Y
AD  - Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical 
      University.
FAU - Yamamoto, Kei
AU  - Yamamoto K
AD  - Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical 
      University.
FAU - Wada, Hiroshi
AU  - Wada H
AD  - Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical 
      University.
FAU - Momomura, Shin-Ichi
AU  - Momomura SI
AD  - Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical 
      University.
FAU - Fujita, Hideo
AU  - Fujita H
AD  - Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical 
      University.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20181010
PL  - Japan
TA  - Int Heart J
JT  - International heart journal
JID - 101244240
SB  - IM
MH  - Aged
MH  - *Coronary Circulation
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Non-ST Elevated Myocardial Infarction/physiopathology/*therapy
MH  - Percutaneous Coronary Intervention/*instrumentation
MH  - Retrospective Studies
MH  - *Stents
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Acute myocardial infarction
OT  - IVUS
OT  - Modest stent expansion strategy
EDAT- 2018/10/12 06:00
MHDA- 2018/12/13 06:00
CRDT- 2018/10/12 06:00
PHST- 2018/10/12 06:00 [pubmed]
PHST- 2018/12/13 06:00 [medline]
PHST- 2018/10/12 06:00 [entrez]
AID - 10.1536/ihj.18-050 [doi]
PST - ppublish
SO  - Int Heart J. 2018 Nov 28;59(6):1237-1245. doi: 10.1536/ihj.18-050. Epub 2018 Oct 
      10.