PMID- 30306747 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20201001 IS - 2092-7355 (Print) IS - 2092-7363 (Electronic) IS - 2092-7355 (Linking) VI - 10 IP - 6 DP - 2018 Nov TI - Pollen-Food Allergy Syndrome in Korean Pollinosis Patients: A Nationwide Survey. PG - 648-661 LID - 10.4168/aair.2018.10.6.648 [doi] AB - PURPOSE: Pollen-food allergy syndrome (PFAS) is an immunoglobulin E (IgE)-mediated allergy in pollinosis patients caused by raw fruits and vegetables and is the most common food allergy in adults. However, there has been no nationwide study on PFAS in Korea. In this study, we investigated the prevalence and clinical characteristics of PFAS in Korea. METHODS: Twenty-two investigators participated in this study, in which patients with allergic rhinoconjunctivitis and/or bronchial asthma with pollen allergy were enrolled. The questionnaires included demographic characteristics, a list of fruits and vegetables, and clinical manifestations of food allergy. Pollen allergy was diagnosed by skin prick test and/or measurement of the serum level of specific IgE. RESULTS: A total of 648 pollinosis patients were enrolled. The prevalence of PFAS was 41.7% (n = 270). PFAS patients exhibited cutaneous (43.0%), respiratory (20.0%), cardiovascular (3.7%) or neurologic symptoms (4.8%) in addition to oropharyngeal symptoms. Anaphylaxis was noted in 8.9% of the PFAS patients. Seventy types of foods were linked to PFAS; e.g., peach (48.5%), apple (46.7%), kiwi (30.4%), peanut (17.4%), plum (16.3%), chestnut (14.8%), pineapple (13.7%), walnut (14.1%), Korean melon (12.6%), tomato (11.9%), melon (11.5%) and apricot (10.7%). Korean foods such as taro/taro stem (8.9%), ginseong (8.2%), perilla leaf (4.4%), bellflower root (4.4%), crown daisy (3.0%), deodeok (3.3%), kudzu root (3.0%) and lotus root (2.6%) were also linked to PFAS. CONCLUSIONS: This was the first nationwide study of PFAS in Korea. The prevalence of PFAS was 41.7%, and 8.9% of the PFAS patients had anaphylaxis. These results will provide clinically useful information to physicians. CI - Copyright (c) 2018 The Korean Academy of Asthma, Allergy and Clinical Immunology . The Korean Academy of Pediatric Allergy and Respiratory Disease. FAU - Kim, Mi Ae AU - Kim MA AUID- ORCID: 0000-0003-1253-6075 AD - Department of Pulmonology, Allergy and Critical Care Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea. FAU - Kim, Dong Kyu AU - Kim DK AUID- ORCID: 0000-0003-4917-0177 AD - Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University Chuncheon Sacred Heart Hospital and Nano-Bio Regenerative Medical Institute, Hallym University College of Medicine, Chuncheon, Korea. FAU - Yang, Hyeon Jong AU - Yang HJ AUID- ORCID: 0000-0002-7287-4300 AD - Department of Pediatrics, Pediatric Allergy and Respiratory Center, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea. pedyang@schmc.ac.kr. FAU - Yoo, Young AU - Yoo Y AUID- ORCID: 0000-0003-3354-6969 AD - Department of Pediatrics, Korea University Anam Hospital, Seoul, Korea. FAU - Ahn, Youngmin AU - Ahn Y AUID- ORCID: 0000-0002-1697-8041 AD - Department of Pediatrics Eulji Hospital, Eulji University, Seoul, Korea. FAU - Park, Hae Sim AU - Park HS AUID- ORCID: 0000-0003-2614-0303 AD - Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea. FAU - Lee, Hyun Jong AU - Lee HJ AUID- ORCID: 0000-0003-0849-0684 AD - Lee & Hong ENT, Sleep and Cosmetic Center, Seongnam, Korea. FAU - Jeong, Yi Yeong AU - Jeong YY AUID- ORCID: 0000-0003-1015-1411 AD - Department of Internal Medicine, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju, Korea. FAU - Kim, Bong Seong AU - Kim BS AUID- ORCID: 0000-0002-3562-3916 AD - Department of Pediatrics, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea. FAU - Bae, Woo Yong AU - Bae WY AUID- ORCID: 0000-0001-5578-0225 AD - Department of Otorhinolaryngology, Head and Neck Surgery, Dong-A University College of Medicine, Busan, Korea. FAU - Jang, An Soo AU - Jang AS AUID- ORCID: 0000-0001-5343-023X AD - Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea. FAU - Park, Yang AU - Park Y AUID- ORCID: 0000-0003-1058-5383 AD - Department of Pediatrics, Wonkwang University Sanbon Hospital, Wonkwang University College of Medicine, Gunpo, Korea. FAU - Koh, Young Il AU - Koh YI AUID- ORCID: 0000-0002-5100-9473 AD - Department of Internal Medicine, Chonnam National University Medical School & Hospital, Gwangju, Korea. FAU - Lee, Jaechun AU - Lee J AD - Department of Internal Medicine, Jeju National University School of Medicine, Jeju, Korea. FAU - Lim, Dae Hyun AU - Lim DH AD - Department of Pediatrics, Inha University Hospital, Inha University College of Medicine, Incheon, Korea. FAU - Kim, Jeong Hee AU - Kim JH AUID- ORCID: 0000-0002-7054-8552 AD - Department of Pediatrics, Inha University Hospital, Inha University College of Medicine, Incheon, Korea. FAU - Lee, Sang Min AU - Lee SM AUID- ORCID: 0000-0002-9568-2096 AD - Division of Pulmonology and Allergy, Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Korea. FAU - Kim, Yong Min AU - Kim YM AUID- ORCID: 0000-0001-5414-8332 AD - Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Korea. FAU - Jun, Young Joon AU - Jun YJ AUID- ORCID: 0000-0002-3687-2367 AD - Department of Otorhinolaryngology-Head & Neck Surgery, College of Medicine, SoonChunHayng University Hospital, Gumi, Korea. FAU - Kim, Hyo Yeol AU - Kim HY AUID- ORCID: 0000-0002-2162-3202 AD - Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. FAU - Kim, Yunsun AU - Kim Y AD - SCH Biomedical Informatics Research Unit, Soonchunhyang University Seoul Hospital, Seoul, Korea. FAU - Choi, Jeong Hee AU - Choi JH AUID- ORCID: 0000-0002-0599-875X AD - Department of Pulmonology and Allergy, Hallym University Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea. mdqueen@hallym.or.kr. CN - Work Group for Rhinitis, the Korean Academy of Asthma, Allergy and Clinical Immunology LA - eng GR - Korean Academy of Asthma, Allergy, and Clinical Immunology/ PT - Journal Article PL - Korea (South) TA - Allergy Asthma Immunol Res JT - Allergy, asthma & immunology research JID - 101518382 EIN - Allergy Asthma Immunol Res. 2019 May;11(3):441-442. PMID: 30912333 PMC - PMC6182195 OTO - NOTNLM OT - Pollen-food allergy syndrome OT - food allergy OT - pollen COIS- There are no financial or other issues that might lead to conflict of interest There are no financial or other issues that might lead to conflict of interests. EDAT- 2018/10/12 06:00 MHDA- 2018/10/12 06:01 PMCR- 2018/07/10 CRDT- 2018/10/12 06:00 PHST- 2018/04/08 00:00 [received] PHST- 2018/05/20 00:00 [revised] PHST- 2018/06/01 00:00 [accepted] PHST- 2018/10/12 06:00 [entrez] PHST- 2018/10/12 06:00 [pubmed] PHST- 2018/10/12 06:01 [medline] PHST- 2018/07/10 00:00 [pmc-release] AID - 10.648 [pii] AID - 10.4168/aair.2018.10.6.648 [doi] PST - ppublish SO - Allergy Asthma Immunol Res. 2018 Nov;10(6):648-661. doi: 10.4168/aair.2018.10.6.648.