PMID- 30315606
OWN - NLM
STAT- MEDLINE
DCOM- 20190405
LR  - 20190405
IS  - 1540-8175 (Electronic)
IS  - 0742-2822 (Linking)
VI  - 35
IP  - 12
DP  - 2018 Dec
TI  - Left ventricular endocardial longitudinal dysfunction persists after acute 
      myocarditis with preserved ejection fraction.
PG  - 1966-1973
LID - 10.1111/echo.14156 [doi]
AB  - BACKGROUND: The aim of present study was to assess left ventricular (LV) 
      myocardial deformation and changes over time in patients with acute myocarditis 
      (AM) with preserved ejection fraction detected by late gadolinium enhancement 
      (LGE) magnetic resonance imaging. METHODS: Thirty-five male patients with AM 
      diagnoses and preserved systolic function based on cardiac magnetic resonance 
      imaging (MRI) were prospectively enrolled. On admission, echocardiography with 
      measurements of global and segmental longitudinal (LS) strains was performed both 
      at the endocardial (ENDO) and epicardial (EPI) levels. Findings were compared to 
      25 control subjects. Twenty-six patients were also monitored over a 22-month 
      follow-up (FU group). RESULTS: On admission, global ENDO-LS was poorer in 
      magnitude in AM (-19.2 +/- 3.1) than in controls (-24.0 +/- 1.05) (P < 0.0001), 
      whereas EPI-LS was not different (-20.6 +/- 3.4 vs -19.7 +/- 6 P = NS). A functional 
      increase in magnitude in both ENDO-LS (-20.8 +/- 5.4, P = NS) and EPI-LS 
      (-22.6 +/- 4.6, P = 0.02) was found in FU vs AM patients. CONCLUSIONS: The present 
      study demonstrates a steady ENDO-LS impairment in infarct-like AM during a 2-year 
      follow-up period, despite a preserved LV ejection fraction.
CI  - (c) 2018 Wiley Periodicals, Inc.
FAU - Di Bella, Gianluca
AU  - Di Bella G
AUID- ORCID: 0000-0001-8933-9884
AD  - Department of Clinical and Experimental Medicine, University of Messina, Messina, 
      Italy.
FAU - Carerj, Scipione
AU  - Carerj S
AD  - Department of Clinical and Experimental Medicine, University of Messina, Messina, 
      Italy.
FAU - Recupero, Antonino
AU  - Recupero A
AD  - Department of Clinical and Experimental Medicine, University of Messina, Messina, 
      Italy.
FAU - Donato, Rocco
AU  - Donato R
AD  - Department of Radiological Science, University of Messina, Messina, Italy.
FAU - Pugliatti, Pietro
AU  - Pugliatti P
AD  - Department of Clinical and Experimental Medicine, University of Messina, Messina, 
      Italy.
FAU - Falanga, Gabriella
AU  - Falanga G
AD  - Department of Clinical and Experimental Medicine, University of Messina, Messina, 
      Italy.
FAU - Pedri, Stefano
AU  - Pedri S
AD  - Esaote-Italy, Florence, Italy.
FAU - Vizzari, Giampiero
AU  - Vizzari G
AD  - Department of Clinical and Experimental Medicine, University of Messina, Messina, 
      Italy.
FAU - Campisi, Mariapaola
AU  - Campisi M
AD  - Department of Clinical and Experimental Medicine, University of Messina, Messina, 
      Italy.
FAU - Zito, Concetta
AU  - Zito C
AD  - Department of Clinical and Experimental Medicine, University of Messina, Messina, 
      Italy.
FAU - de Gregorio, Cesare
AU  - de Gregorio C
AD  - Department of Clinical and Experimental Medicine, University of Messina, Messina, 
      Italy.
LA  - eng
PT  - Journal Article
DEP - 20181012
PL  - United States
TA  - Echocardiography
JT  - Echocardiography (Mount Kisco, N.Y.)
JID - 8511187
SB  - IM
MH  - Acute Disease
MH  - Adult
MH  - Disease Progression
MH  - Echocardiography, Doppler, Pulsed
MH  - Endocardium/*diagnostic imaging
MH  - Follow-Up Studies
MH  - Heart Ventricles/*diagnostic imaging/physiopathology
MH  - Humans
MH  - Magnetic Resonance Imaging, Cine
MH  - Male
MH  - Myocarditis/*complications/diagnosis/physiopathology
MH  - Retrospective Studies
MH  - Stroke Volume/*physiology
MH  - Time Factors
MH  - Ventricular Dysfunction, Left/diagnosis/etiology/*physiopathology
MH  - Ventricular Function, Left/*physiology
OTO - NOTNLM
OT  - acute myocarditis
OT  - cardiac magnetic resonance
OT  - chronic myocarditis
OT  - strain echocardiography
EDAT- 2018/10/14 06:00
MHDA- 2019/04/06 06:00
CRDT- 2018/10/14 06:00
PHST- 2018/08/27 00:00 [received]
PHST- 2018/09/12 00:00 [accepted]
PHST- 2018/10/14 06:00 [pubmed]
PHST- 2019/04/06 06:00 [medline]
PHST- 2018/10/14 06:00 [entrez]
AID - 10.1111/echo.14156 [doi]
PST - ppublish
SO  - Echocardiography. 2018 Dec;35(12):1966-1973. doi: 10.1111/echo.14156. Epub 2018 
      Oct 12.