PMID- 3031617
OWN - NLM
STAT- MEDLINE
DCOM- 19870521
LR  - 20190501
IS  - 0305-1048 (Print)
IS  - 1362-4962 (Electronic)
IS  - 0305-1048 (Linking)
VI  - 15
IP  - 7
DP  - 1987 Apr 10
TI  - Nonrandom distribution of MMTV proviral sequences in the mouse genome.
PG  - 3009-22
AB  - Integrated sequences of mouse mammary tumor virus (MMTV) have been localized in 
      the genomes of five inbred mouse strains (Balb/c, C3H, DBA/2, A.TH, 129-SV) and 
      one mammary tumor cell line (GR). Two major classes of MMTV sequences have been 
      detected in mouse DNA fractions as obtained by Cs2SO4/BAMD 
      (3,6-bis-(acetatomercurimethyl)dioxane) density gradient centrifugation. The 
      first one corresponds to previously described endogenous sequences (Mtv loci), 
      whereas the second one corresponds to endogenous sequences not previously known, 
      and/or recently acquired; in the case of GR cells exogenous sequences may also be 
      present in this class. The genome distribution is somewhat different for the two 
      classes of sequences, the first one being practically only present in the 
      lightest DNA segments of the mouse genome (GC congruent to 38%); the second one 
      being also represented in heavier segments (GC congruent to 43%). This 
      integration pattern suggests that "ancient" endogenous sequences are practically 
      only localized in genome segments of roughly matching composition, whereas 
      exogenous and recently acquired endogenous MMTV sequences may also be present in 
      heavier fractions.
FAU - Salinas, J
AU  - Salinas J
FAU - Zerial, M
AU  - Zerial M
FAU - Filipski, J
AU  - Filipski J
FAU - Crepin, M
AU  - Crepin M
FAU - Bernardi, G
AU  - Bernardi G
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Nucleic Acids Res
JT  - Nucleic acids research
JID - 0411011
SB  - IM
MH  - Animals
MH  - Base Sequence
MH  - Cell Line
MH  - Female
MH  - *Genes
MH  - *Genes, Viral
MH  - Mammary Neoplasms, Experimental/microbiology
MH  - Mammary Tumor Virus, Mouse/*genetics
MH  - Mice
MH  - Mice, Inbred Strains/*genetics
MH  - Species Specificity
PMC - PMC340712
EDAT- 1987/04/10 00:00
MHDA- 1987/04/10 00:01
PMCR- 1987/04/10
CRDT- 1987/04/10 00:00
PHST- 1987/04/10 00:00 [pubmed]
PHST- 1987/04/10 00:01 [medline]
PHST- 1987/04/10 00:00 [entrez]
PHST- 1987/04/10 00:00 [pmc-release]
AID - 10.1093/nar/15.7.3009 [doi]
PST - ppublish
SO  - Nucleic Acids Res. 1987 Apr 10;15(7):3009-22. doi: 10.1093/nar/15.7.3009.