PMID- 30317398
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220408
IS  - 1869-5760 (Print)
IS  - 1869-5760 (Electronic)
IS  - 1869-5760 (Linking)
VI  - 8
IP  - 1
DP  - 2018 Oct 13
TI  - Swept-source OCT in patients with multiple evanescent white dot syndrome.
PG  - 16
LID - 10.1186/s12348-018-0159-2 [doi]
LID - 16
AB  - BACKGROUND: Swept-source optical coherence tomography (SS-OCT) has a higher 
      scanning rate and longer wavelength in comparison with spectral-domain OCT 
      (SD-OCT), allowing an improved imaging of retinal vascular plexuses and 
      choriocapillaris. The present two patients diagnosed with multiple evanescent 
      white dot syndrome (MEWDS) underwent fundus autofluorescence (FAF), en-face 
      SS-OCT, and SS-OCT angiography (OCTA) imaging, and its features were described 
      and correlated. RESULTS: The clinical and imaging findings of both cases were 
      consistent with the diagnosis of MEWDS. Color fundus photograph revealed subtle 
      deep retinal white spots in the posterior pole and around the optic disk. FAF 
      showed several hyperautofluorescent lesions corresponding topographically to the 
      subtle deep retinal white lesions observed on color fundus photographs. 
      Cross-sectional SS-OCT showed disruption of the ellipsoid zone (EZ) within the 
      macular area in all study patients. En-face SS-OCT at the level of the outer 
      retina showed lower reflectivity correspondent to the diffuse attenuation due to 
      the EZ disruption on cross-sectional OCT. SS-OCTA demonstrated flow preservation 
      within the retinal vasculature and choriocapillaris. CONCLUSIONS: SS-OCT imaging 
      allows a better visualization of the choriocapillaris, and its normal appearance 
      in MEWDS may suggest that the outer retina and photoreceptors represent the 
      primary site of inflammation.
FAU - Pereira, Felipe
AU  - Pereira F
AD  - Department of Ophthalmology, Federal University of Sao Paulo, Rua Botucatu, 821, 
      Vila Clementino, Sao Paulo, SP, 04023-062, Brazil.
FAU - Lima, Luiz H
AU  - Lima LH
AUID- ORCID: 0000-0001-7304-909X
AD  - Department of Ophthalmology, Federal University of Sao Paulo, Rua Botucatu, 821, 
      Vila Clementino, Sao Paulo, SP, 04023-062, Brazil. luizlima9@gmail.com.
FAU - de Azevedo, Alexandre Gomes B
AU  - de Azevedo AGB
AD  - Department of Ophthalmology, Federal University of Sao Paulo, Rua Botucatu, 821, 
      Vila Clementino, Sao Paulo, SP, 04023-062, Brazil.
FAU - Zett, Claudio
AU  - Zett C
AD  - Department of Ophthalmology, Federal University of Sao Paulo, Rua Botucatu, 821, 
      Vila Clementino, Sao Paulo, SP, 04023-062, Brazil.
AD  - Pontificia Universidad Catolica de Valparaiso, Valparaiso, Chile.
FAU - Farah, Michel E
AU  - Farah ME
AD  - Department of Ophthalmology, Federal University of Sao Paulo, Rua Botucatu, 821, 
      Vila Clementino, Sao Paulo, SP, 04023-062, Brazil.
AD  - Vision Institute, Sao Paulo, Brazil.
FAU - Belfort, Rubens Jr
AU  - Belfort R Jr
AD  - Department of Ophthalmology, Federal University of Sao Paulo, Rua Botucatu, 821, 
      Vila Clementino, Sao Paulo, SP, 04023-062, Brazil.
AD  - Vision Institute, Sao Paulo, Brazil.
LA  - eng
PT  - Journal Article
DEP - 20181013
PL  - Germany
TA  - J Ophthalmic Inflamm Infect
JT  - Journal of ophthalmic inflammation and infection
JID - 101553216
PMC - PMC6186261
OTO - NOTNLM
OT  - Choriocapillaris
OT  - MEWDS
OT  - Outer retina
OT  - Swept-source OCT
COIS- ETHICS APPROVAL AND CONSENT TO PARTICIPATE: Ethics approval and consent to 
      participate were obtained for this case report. CONSENT FOR PUBLICATION: The 
      consent for publication was obtained from the study patients. COMPETING 
      INTERESTS: The authors declare that they have no competing interests. PUBLISHER'S 
      NOTE: Springer Nature remains neutral with regard to jurisdictional claims in 
      published maps and institutional affiliations.
EDAT- 2018/10/15 06:00
MHDA- 2018/10/15 06:01
PMCR- 2018/10/13
CRDT- 2018/10/15 06:00
PHST- 2018/08/21 00:00 [received]
PHST- 2018/10/02 00:00 [accepted]
PHST- 2018/10/15 06:00 [entrez]
PHST- 2018/10/15 06:00 [pubmed]
PHST- 2018/10/15 06:01 [medline]
PHST- 2018/10/13 00:00 [pmc-release]
AID - 10.1186/s12348-018-0159-2 [pii]
AID - 159 [pii]
AID - 10.1186/s12348-018-0159-2 [doi]
PST - epublish
SO  - J Ophthalmic Inflamm Infect. 2018 Oct 13;8(1):16. doi: 10.1186/s12348-018-0159-2.