PMID- 30319093
OWN - NLM
STAT- MEDLINE
DCOM- 20190930
LR  - 20190930
IS  - 1097-685X (Electronic)
IS  - 0022-5223 (Linking)
VI  - 156
IP  - 6
DP  - 2018 Dec
TI  - Long-term health-related quality of life and survival after cardiac surgery: A 
      prospective study.
PG  - 2183-2190.e2
LID - S0022-5223(18)31523-X [pii]
LID - 10.1016/j.jtcvs.2018.05.087 [doi]
AB  - OBJECTIVES: Health-related quality of life (HRQOL) is an important end point 
      after cardiac surgery, particularly in patients of older age. However, 
      prospective long-term studies describing the trajectory of HRQOL after cardiac 
      surgery are still scarce. Therefore, the aim was to assess survival, functional 
      status, and trajectory of HRQOL 10 years after cardiac surgery. METHODS: In a 
      prospective population-based study, 534 patients (23% aged 75 years or older, 67% 
      male) were consecutively included before surgery. Functional status was measured 
      according to self-assigned New York Heart Association (NYHA) classification. 
      HRQOL was measured using the Short-Form Health Survey (SF-36). Questionnaires 
      were given to the patients at baseline and sent by post at 6 and 12 months, and 5 
      and 10 years after surgery. RESULTS: Three hundred fifty-two patients were 
      eligible after 10 years, 274 responded (77.8%). Total survival at 10 years was 
      67.8%. Patients aged 75 years or older at surgery had lower survival rates than 
      younger patients (44.6% vs 74.6%, P < .001). Seven of 8 SF-36 subscales were 
      improved at 10 years compared with baseline. Older patients improved less than 
      younger patients and linear mixed models showed that older patients had 
      significantly worse trajectories on 3 of 8 SF-36 subscales. NYHA classification 
      improved from baseline to 10 years also among older patients, with 59% in NYHA 
      class III/IV at baseline compared with 30.3% after 10 years (P < .013). 
      CONCLUSIONS: HRQOL and function improved from before to 10 years after cardiac 
      surgery, also for older patients. These long-term results are of major importance 
      when discussing the use of health care resources and patient-centered clinical 
      decision-making.
CI  - Copyright (c) 2018 The American Association for Thoracic Surgery. Published by 
      Elsevier Inc. All rights reserved.
FAU - Gjeilo, Kari Hanne
AU  - Gjeilo KH
AD  - Department of Cardiothoracic Surgery, St Olavs Hospital, Trondheim University 
      Hospital, Trondheim, Norway; Department of Cardiology, St Olavs Hospital, 
      Trondheim University Hospital, Trondheim, Norway; National Competence Centre for 
      Complex Symptom Disorders, St Olavs Hospital, Trondheim University Hospital, 
      Trondheim, Norway; Department of Circulation and Medical Imaging, Faculty of 
      Medicine and Health Sciences, NTNU, Norwegian University of Science and 
      Technology, Trondheim, Norway. Electronic address: kari.hanne.gjeilo@stolav.no.
FAU - Stenseth, Roar
AU  - Stenseth R
AD  - Department of Circulation and Medical Imaging, Faculty of Medicine and Health 
      Sciences, NTNU, Norwegian University of Science and Technology, Trondheim, 
      Norway; Department of Cardiothoracic Anaesthesiology, St Olavs Hospital, 
      Trondheim University Hospital, Trondheim, Norway.
FAU - Wahba, Alexander
AU  - Wahba A
AD  - Department of Cardiothoracic Surgery, St Olavs Hospital, Trondheim University 
      Hospital, Trondheim, Norway; Department of Circulation and Medical Imaging, 
      Faculty of Medicine and Health Sciences, NTNU, Norwegian University of Science 
      and Technology, Trondheim, Norway.
FAU - Lydersen, Stian
AU  - Lydersen S
AD  - Department of Mental Health, Regional Centre for Child and Youth Mental Health 
      and Child Welfare-Central Norway, Faculty of Medicine and Health Sciences, NTNU, 
      Norwegian University of Science and Technology, Trondheim, Norway.
FAU - Klepstad, Pal
AU  - Klepstad P
AD  - Department of Circulation and Medical Imaging, Faculty of Medicine and Health 
      Sciences, NTNU, Norwegian University of Science and Technology, Trondheim, 
      Norway; Department of Intensive Care Medicine, St Olavs Hospital, Trondheim 
      University Hospital, Trondheim, Norway.
LA  - eng
PT  - Journal Article
PT  - Video-Audio Media
DEP - 20180607
PL  - United States
TA  - J Thorac Cardiovasc Surg
JT  - The Journal of thoracic and cardiovascular surgery
JID - 0376343
SB  - IM
CIN - J Thorac Cardiovasc Surg. 2018 Dec;156(6):2192-2193. PMID: 29961589
CIN - J Thorac Cardiovasc Surg. 2018 Dec;156(6):2191. PMID: 30007782
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Aged, 80 and over
MH  - *Cardiac Surgical Procedures/adverse effects/mortality
MH  - Female
MH  - Health Status
MH  - Humans
MH  - Longitudinal Studies
MH  - Male
MH  - Mental Health
MH  - Middle Aged
MH  - Patient Reported Outcome Measures
MH  - Prospective Studies
MH  - *Quality of Life
MH  - Risk Assessment
MH  - Risk Factors
MH  - *Survivors/psychology
MH  - Time Factors
MH  - Treatment Outcome
OTO - NOTNLM
OT  - cardiac surgery
OT  - health surveys
OT  - patient-reported outcomes
OT  - quality of life
OT  - survival
EDAT- 2018/10/16 06:00
MHDA- 2019/10/01 06:00
CRDT- 2018/10/16 06:00
PHST- 2017/10/27 00:00 [received]
PHST- 2018/05/04 00:00 [revised]
PHST- 2018/05/12 00:00 [accepted]
PHST- 2018/10/16 06:00 [pubmed]
PHST- 2019/10/01 06:00 [medline]
PHST- 2018/10/16 06:00 [entrez]
AID - S0022-5223(18)31523-X [pii]
AID - 10.1016/j.jtcvs.2018.05.087 [doi]
PST - ppublish
SO  - J Thorac Cardiovasc Surg. 2018 Dec;156(6):2183-2190.e2. doi: 
      10.1016/j.jtcvs.2018.05.087. Epub 2018 Jun 7.