PMID- 30337168
OWN - NLM
STAT- MEDLINE
DCOM- 20181212
LR  - 20181212
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1578
DP  - 2018 Nov 30
TI  - Ionic liquid-copolymerized monolith incorporated with zeolitic imidazolate 
      framework-8 as stationary phases for enhancing reversed phase selectivity in 
      capillary electrochromatography.
PG  - 99-105
LID - S0021-9673(18)31269-X [pii]
LID - 10.1016/j.chroma.2018.10.008 [doi]
AB  - A novel ionic liquid (1-allyl-methylimidazolium chloride, AlMeIm(+)Cl(-)) polymer 
      monolith poly(ionic liquid-co-ethylene dimethacrylate) incorporated with zeolitic 
      imidazolate framework-8 (ZIF-8-poly(IL-co-EDMA)) was firstly synthesized as 
      stationary phases of monolithic column for capillary electrochromatography by 
      one-step copolymerization. Incorporation of ZIF-8 into ionic liquid polymer 
      monolith evidently enhanced the separation selectivity for four alkylbenzenes in 
      reversed phase capillary electrochromatography (CEC), due to the synergistic 
      effect derived from the same imidazole ring structure of ionic liquid and organic 
      ligands of ZIF-8. Meanwhile, electroosmotic flow (EOF) was generated by ionic 
      liquid in a wide range of pH values from 2.0 to 12.0. The resultant monolithic 
      columns were characterized by scanning electron microscopy (SEM) and Fourier 
      transform infrared (FT-IR). The results indicated that the prepared monolithic 
      columns had good permeability and mechanism stability. The resultant monolithic 
      columns were applied for the separation of neutral compounds, anilines and 
      phenols. The highest column efficiency was 2.07 x 10(5) plates m(-1) (theoretical 
      plates, N) for toluene. Under optimal conditions, reproducibility was obtained 
      with relative standard deviations (RSDs) of the retention time for run-to-run, 
      day-to-day, column-to-column and batch-to-batch were in the range of 
      1.58 - 3.19%, 1.92 - 3.87%, 3.84 - 4.96% and 2.63 - 4.33%, respectively. 
      Incorporation ZIF-8 into ionic liquid polymer monolith was a promising way for 
      the application of new materials in the fabrication of novel monolithic columns.
CI  - Copyright (c) 2018 Elsevier B.V. All rights reserved.
FAU - Mao, Zhenkun
AU  - Mao Z
AD  - Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of 
      Education, Wuhan University School of Pharmaceutical Sciences, Wuhan, 430071, 
      China.
FAU - Bao, Tao
AU  - Bao T
AD  - Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of 
      Education, Wuhan University School of Pharmaceutical Sciences, Wuhan, 430071, 
      China.
FAU - Li, Zhentao
AU  - Li Z
AD  - Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of 
      Education, Wuhan University School of Pharmaceutical Sciences, Wuhan, 430071, 
      China.
FAU - Chen, Zilin
AU  - Chen Z
AD  - Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of 
      Education, Wuhan University School of Pharmaceutical Sciences, Wuhan, 430071, 
      China. Electronic address: chenzl@whu.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20181010
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Imidazoles)
RN  - 0 (Ionic Liquids)
RN  - 0 (Ions)
RN  - 0 (Methacrylates)
RN  - 0 (Phenols)
RN  - 0 (Polymers)
RN  - 1318-02-1 (Zeolites)
RN  - 3FPU23BG52 (Toluene)
RN  - 7BK5G69305 (ethylene dimethacrylate)
RN  - 7GBN705NH1 (imidazole)
SB  - IM
MH  - *Capillary Electrochromatography
MH  - Chemistry Techniques, Analytical/*methods/standards
MH  - Electroosmosis
MH  - Imidazoles/*chemistry
MH  - Ionic Liquids/*chemistry
MH  - Ions
MH  - Methacrylates/chemistry
MH  - Phenols/isolation & purification
MH  - Polymerization
MH  - Polymers/chemistry
MH  - Reproducibility of Results
MH  - Spectroscopy, Fourier Transform Infrared
MH  - Toluene/isolation & purification
MH  - Zeolites/chemistry
OTO - NOTNLM
OT  - Ionic liquid polymer
OT  - Monolithic column
OT  - Reversed phase capillary electrochromatography
OT  - Synergistic effect
OT  - Zeolitic imidazolate frameworks
EDAT- 2018/10/20 06:00
MHDA- 2018/12/13 06:00
CRDT- 2018/10/20 06:00
PHST- 2018/08/05 00:00 [received]
PHST- 2018/10/05 00:00 [revised]
PHST- 2018/10/09 00:00 [accepted]
PHST- 2018/10/20 06:00 [pubmed]
PHST- 2018/12/13 06:00 [medline]
PHST- 2018/10/20 06:00 [entrez]
AID - S0021-9673(18)31269-X [pii]
AID - 10.1016/j.chroma.2018.10.008 [doi]
PST - ppublish
SO  - J Chromatogr A. 2018 Nov 30;1578:99-105. doi: 10.1016/j.chroma.2018.10.008. Epub 
      2018 Oct 10.