PMID- 30345090
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240402
IS  - 2062-509X (Print)
IS  - 2062-8633 (Electronic)
IS  - 2062-509X (Linking)
VI  - 8
IP  - 3
DP  - 2018 Sep 28
TI  - Determination of Antimicrobial Activity of Some Commercial Fruit (Apple, Papaya, 
      Lemon and Strawberry) Against Bacteria Causing Urinary Tract Infection.
PG  - 95-99
LID - 10.1556/1886.2018.00014 [doi]
AB  - Urinary Tract Infection (UTI) is a worldwide phenomenon in modern times, in which 
      the dependency on antibiotics for its treatment is increasing. The current study 
      was conducted in order to find alternatives to antibiotics by investigating some 
      commercial fruits for their antimicrobial activity. The fruits in this study 
      included green apple (Malus domestica), papaya (Carica papaya), lemon (Citrus 
      limon), and strawberry (Fragaria ananassa), which were used to prepare methanolic 
      and ethanolic extracts through Soxhlet extraction technique. The extracts were 
      used against bacteria that cause UTI, and five different strains were selected: 
      E. coli (ATCC: 15922), E. coli (ATCC: 25922), Pseudomonas aeruginosa (ATCC: 
      27853), Enterococcus faecalis (ATCC: 29212), and Klebsiella pneumoniae. 
      Antimicrobial tests of the extracts were conducted by following the agar well 
      diffusion method, where ciprofloxacin was used as a positive control, and 
      autoclaved distilled water was used as a negative control. Among the fruits, 
      apple and papaya extracts did not show any zone of inhibition against any of the 
      tested bacteria. However, both lemon and strawberry extracts showed inhibition 
      zone against all of the mentioned bacteria. The ethanolic extracts of lemon and 
      strawberry were more potent than their methanolic extracts. Lemon ethanolic 
      extract showed the highest zone of inhibition against Pseudomonas aeruginosa 
      (ATCC: 27853) (18.34 +/- 0.58) and lowest one against Klebsiella pneumoniae (16.00 
      +/- 1.00). Strawberry ethanolic extracts showed the highest zone of inhibition 
      against Pseudomonas aeruginosa (ATCC: 27853) (16.33 +/- 0.58) and the lowest one 
      against Klebsiella pneumoniae (13.33 +/- 0.58). As antibiotic resistance is paving 
      the way for multi-drug resistant bacteria, the results of lemon and strawberry 
      can be considered to be used as an antimicrobial agent in treating urinary tract 
      infections.
FAU - Liya, Sabiha Jahan
AU  - Liya SJ
AD  - Department of Mathematics and Natural Sciences, BRAC University, 66 Mohakhali, 
      Dhaka-1212, Bangladesh.
FAU - Siddique, Romana
AU  - Siddique R
AD  - Department of Mathematics and Natural Sciences, BRAC University, 66 Mohakhali, 
      Dhaka-1212, Bangladesh.
LA  - eng
PT  - Journal Article
DEP - 20180816
PL  - Hungary
TA  - Eur J Microbiol Immunol (Bp)
JT  - European journal of microbiology & immunology
JID - 101569896
PMC - PMC6186015
OTO - NOTNLM
OT  - Soxhlet
OT  - UTI
OT  - agar well diffusion
OT  - ethanolic extracts
OT  - methanolic extracts
COIS- Conflict of Interest There is no conflict of interest among the authors.
EDAT- 2018/10/23 06:00
MHDA- 2018/10/23 06:01
PMCR- 2018/08/16
CRDT- 2018/10/23 06:00
PHST- 2018/06/12 00:00 [received]
PHST- 2018/07/11 00:00 [accepted]
PHST- 2018/10/23 06:00 [entrez]
PHST- 2018/10/23 06:00 [pubmed]
PHST- 2018/10/23 06:01 [medline]
PHST- 2018/08/16 00:00 [pmc-release]
AID - 10.1556/1886.2018.00014 [doi]
PST - epublish
SO  - Eur J Microbiol Immunol (Bp). 2018 Aug 16;8(3):95-99. doi: 
      10.1556/1886.2018.00014. eCollection 2018 Sep 28.