PMID- 30351489
OWN - NLM
STAT- MEDLINE
DCOM- 20190514
LR  - 20190514
IS  - 1747-0803 (Electronic)
IS  - 1747-079X (Linking)
VI  - 14
IP  - 2
DP  - 2019 Mar
TI  - Bioelectrical impedance analysis in the management of heart failure in adult 
      patients with congenital heart disease.
PG  - 167-175
LID - 10.1111/chd.12683 [doi]
AB  - OBJECTIVE: The recognition of fluid retention is critical in treating heart 
      failure (HF). Bioelectrical impedance analysis (BIA) is a well-known noninvasive 
      method; however, data on its role in managing patients with congenital heart 
      disease (CHD) are limited. Here, we aimed to clarify the correlation between BIA 
      and HF severity as well as the prognostic value of BIA in adult patients with 
      CHD. DESIGN: This prospective single-center study included 170 patients with CHD 
      admitted between 2013 and 2015. We evaluated BIA parameters (intra- and 
      extracellular water, protein, and mineral levels, edema index [EI, extracellular 
      water-to-total body water ratio]), laboratory values, and HF-related admission 
      prevalence. RESULTS: Patients with New York Heart Association (NYHA) functional 
      classes III-IV had a higher EI than those with NYHA classes I-II (mean +/- SD, 
      0.398 +/- 0.011 vs 0.384 +/- 0.017, P < .001). EI was significantly correlated with 
      brain natriuretic peptide level (r = 0.51, P < .001). During the mean follow-up 
      period of 7.1 months, Kaplan-Meier analysis showed that a discharge EI > 0.386, 
      the median value in the present study, was significantly associated with a future 
      increased risk of HF-related admission (HR = 4.15, 95% CI = 1.70－11.58, 
      P < .001). A body weight reduction during hospitalization was also related to EI 
      reduction. CONCLUSIONS: EI determined using BIA could be a useful marker for HF 
      severity that could predict future HF-related admissions in adult patients with 
      CHD.
CI  - (c) 2018 Wiley Periodicals, Inc.
FAU - Sato, Masaki
AU  - Sato M
AUID- ORCID: 0000-0002-5444-8607
AD  - Department of Pediatric Cardiology, Tokyo Women's Medical University, Tokyo, 
      Japan.
FAU - Inai, Kei
AU  - Inai K
AD  - Department of Pediatric Cardiology, Tokyo Women's Medical University, Tokyo, 
      Japan.
AD  - Division of Adult Congenital Heart Disease Pathophysiology and Lifelong Care, 
      Tokyo Women's Medical University, Tokyo, Japan.
FAU - Shimizu, Mikiko
AU  - Shimizu M
AD  - Department of Pediatric Cardiology, Tokyo Women's Medical University, Tokyo, 
      Japan.
FAU - Sugiyama, Hisashi
AU  - Sugiyama H
AD  - Department of Pediatric Cardiology, Tokyo Women's Medical University, Tokyo, 
      Japan.
FAU - Nakanishi, Toshio
AU  - Nakanishi T
AD  - Division of Adult Congenital Heart Disease Pathophysiology and Lifelong Care, 
      Tokyo Women's Medical University, Tokyo, Japan.
LA  - eng
PT  - Journal Article
DEP - 20181023
PL  - United States
TA  - Congenit Heart Dis
JT  - Congenital heart disease
JID - 101256510
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Body Weight
MH  - Cardiac Catheterization
MH  - *Disease Management
MH  - Echocardiography, Doppler
MH  - Echocardiography, Transesophageal
MH  - Electric Impedance
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Defects, Congenital/*complications/diagnosis/physiopathology
MH  - Heart Failure/etiology/*physiopathology/therapy
MH  - Hospitalization/trends
MH  - Humans
MH  - Male
MH  - Prognosis
MH  - Prospective Studies
MH  - Severity of Illness Index
MH  - Young Adult
OTO - NOTNLM
OT  - bioelectrical impedance analysis
OT  - congenital heart disease
OT  - fluid retention
OT  - heart failure
EDAT- 2018/10/24 06:00
MHDA- 2019/05/15 06:00
CRDT- 2018/10/24 06:00
PHST- 2018/01/19 00:00 [received]
PHST- 2018/09/01 00:00 [revised]
PHST- 2018/09/12 00:00 [accepted]
PHST- 2018/10/24 06:00 [pubmed]
PHST- 2019/05/15 06:00 [medline]
PHST- 2018/10/24 06:00 [entrez]
AID - 10.1111/chd.12683 [doi]
PST - ppublish
SO  - Congenit Heart Dis. 2019 Mar;14(2):167-175. doi: 10.1111/chd.12683. Epub 2018 Oct 
      23.