PMID- 30352431 OWN - NLM STAT- MEDLINE DCOM- 20190128 LR - 20220129 IS - 1421-9824 (Electronic) IS - 1420-8008 (Linking) VI - 46 IP - 3-4 DP - 2018 TI - Screening for Aphasia in NeuroDegeneration for the Diagnosis of Patients with Primary Progressive Aphasia: Clinical Validity and Psychometric Properties. PG - 243-252 LID - 10.1159/000492632 [doi] AB - BACKGROUND: We evaluated the psychometric proprieties of the Screening for Aphasia in NeuroDegeneration (SAND) battery in Italian primary progressive aphasia (PPA) and movement disorder (MD) patients. METHODS: The sample included 30 consecutive PPA and 45 MD patients who completed the SAND battery together with a clinical interview and a neurological/neuropsychological examination and 130 healthy controls (HC). RESULTS: The SAND battery showed good internal consistency and good convergent and divergent validity. receiver operating characteristic analysis revealed an area under the curve of 0.978 for PPA versus HC and of 0.786 for PPA versus MD. A cutoff >/=3 gave a sensitivity of 0.933% and a specificity of 0.946% for discriminating PPA versus HC, whereas a cutoff >/=5 gave a sensitivity of 0.767% and a specificity of 0.667% for discriminating PPA versus MD. CONCLUSION: These results indicate that the SAND battery is an adequate, reliable, and valid diagnostic tool for PPA. CI - (c) 2018 S. Karger AG, Basel. FAU - Battista, Petronilla AU - Battista P AD - Department of Basic Medical Sciences, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy. AD - Neurodegenerative Disease Unit, Department of Clinical Research in Neurology, University of Bari Aldo Moro, "Pia Fondazione Cardinale G. Panico", Tricase, Italy. AD - NEUROFARBA - Dipartimento di Neuroscienze, Psicologia, Area del Farmaco e Salute del Bambino, Universita di Firenze, Florence, Italy. FAU - Catricala, Eleonora AU - Catricala E AD - Center for Neurocognition and Theoretical Syntax, Scuola Universitaria Superiore IUSS Pavia, Pavia, Italy. FAU - Piccininni, Marco AU - Piccininni M AD - Department of Basic Medical Sciences, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy. AD - Neurodegenerative Disease Unit, Department of Clinical Research in Neurology, University of Bari Aldo Moro, "Pia Fondazione Cardinale G. Panico", Tricase, Italy. FAU - Copetti, Massimiliano AU - Copetti M AD - Biostatistics Unit, IRCCS-Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy. FAU - Esposito, Valentina AU - Esposito V AD - Department of Specialistic Rehabilitation of Neurological, Cognitive, and Motor Disorders, IRCCS San Raffaele Hospital and Vita-Salute University, Milan, Italy. AD - Universita Vita-Salute San Raffaele, Milan, Italy. FAU - Polito, Cristina AU - Polito C AD - NEUROFARBA - Dipartimento di Neuroscienze, Psicologia, Area del Farmaco e Salute del Bambino, Universita di Firenze, Florence, Italy. FAU - Miozzo, Antonio AU - Miozzo A AD - Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy. FAU - Gobbi, Elena AU - Gobbi E AD - Universita Vita-Salute San Raffaele, Milan, Italy. AD - IRCCS S. Giovanni di Dio Fatebenefratelli, Brescia, Italy. FAU - Cuoco, Sofia AU - Cuoco S AD - Dipartimento di Medicina e Chirurgia, Universita di Salerno, Salerno, Italy. FAU - Boschi, Veronica AU - Boschi V AD - Center for Neurocognition and Theoretical Syntax, Scuola Universitaria Superiore IUSS Pavia, Pavia, Italy. FAU - Picillo, Marina AU - Picillo M AD - Dipartimento di Medicina e Chirurgia, Universita di Salerno, Salerno, Italy. FAU - Sorbi, Sandro AU - Sorbi S AD - NEUROFARBA - Dipartimento di Neuroscienze, Psicologia, Area del Farmaco e Salute del Bambino, Universita di Firenze, Florence, Italy. AD - IRCCS Don Gnocchi Firenze, Florence, Italy. FAU - Barone, Paolo AU - Barone P AD - Dipartimento di Medicina e Chirurgia, Universita di Salerno, Salerno, Italy. FAU - Iannaccone, Sandro AU - Iannaccone S AD - Department of Specialistic Rehabilitation of Neurological, Cognitive, and Motor Disorders, IRCCS San Raffaele Hospital and Vita-Salute University, Milan, Italy. FAU - Garrard, Peter AU - Garrard P AD - Neuroscience Research Center, St George's University of London, London, United Kingdom. FAU - Logroscino, Giancarlo AU - Logroscino G AD - Department of Basic Medical Sciences, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy. AD - Neurodegenerative Disease Unit, Department of Clinical Research in Neurology, University of Bari Aldo Moro, "Pia Fondazione Cardinale G. Panico", Tricase, Italy. FAU - Cappa, Stefano F AU - Cappa SF AD - Center for Neurocognition and Theoretical Syntax, Scuola Universitaria Superiore IUSS Pavia, Pavia, Italystefano.cappa@iusspavia.it. AD - IRCCS S. Giovanni di Dio Fatebenefratelli, Brescia, Italystefano.cappa@iusspavia.it. LA - eng GR - G0801370/MRC_/Medical Research Council/United Kingdom GR - MR/N025881/1/MRC_/Medical Research Council/United Kingdom PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20181023 PL - Switzerland TA - Dement Geriatr Cogn Disord JT - Dementia and geriatric cognitive disorders JID - 9705200 SB - IM MH - Aged MH - *Aphasia, Primary Progressive/diagnosis/etiology MH - Female MH - Humans MH - Italy MH - Male MH - Mass Screening/methods MH - Middle Aged MH - *Movement Disorders/diagnosis/etiology MH - Neurodegenerative Diseases/*complications MH - Neurologic Examination/methods MH - Neuropsychological Tests MH - Psychometrics/methods MH - ROC Curve MH - Reproducibility of Results MH - Speech Production Measurement/methods OTO - NOTNLM OT - Dementia OT - Diagnostic accuracy OT - Language impairment OT - Screening instrument OT - Speech-language assessment EDAT- 2018/10/24 06:00 MHDA- 2019/01/29 06:00 CRDT- 2018/10/24 06:00 PHST- 2018/04/18 00:00 [received] PHST- 2018/08/02 00:00 [accepted] PHST- 2018/10/24 06:00 [pubmed] PHST- 2019/01/29 06:00 [medline] PHST- 2018/10/24 06:00 [entrez] AID - 000492632 [pii] AID - 10.1159/000492632 [doi] PST - ppublish SO - Dement Geriatr Cogn Disord. 2018;46(3-4):243-252. doi: 10.1159/000492632. Epub 2018 Oct 23.