PMID- 30353114
OWN - NLM
STAT- MEDLINE
DCOM- 20191125
LR  - 20191125
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 8
IP  - 1
DP  - 2018 Oct 23
TI  - Modulation of auditory sensory memory by chronic clinical pain and acute 
      experimental pain: a mismatch negativity study.
PG  - 15673
LID - 10.1038/s41598-018-34099-y [doi]
LID - 15673
AB  - Pain, especially chronic pain, can lead to cognitive deficits. Mismatch 
      negativity (MMN) is a change-specific component of the auditory event-related 
      brain potential (ERP) that is thought to provide a unique window into sensory 
      memory processes. The present study was designed to determine how chronic and 
      acute pain affects auditory sensory memory. In experiment 1, MMNs elicited by 
      standard and deviant auditory stimuli at short and long inter-stimulus intervals 
      (ISIs) were compared between trigeminal neuralgia (TN) patients and 
      demographically matched healthy controls (HCs). The TN patients were found to 
      have stronger attenuation of the MMN at longer ISIs than HCs. Correlation 
      analysis revealed a significant positive correlation between the sensory subscale 
      of McGill Pain Questionnaire and MMN amplitude reduction across ISI conditions. 
      In experiment 2, MMNs recorded before, during, and after the cold pressor test 
      were compared in healthy subjects. MMN amplitude was significantly reduced during 
      pain exposure and recovered immediately thereafter. These results suggest that 
      both chronic pain and acute pain can interfere with automatic change detection 
      processes in the brain. This study provides the first evidence that chronic pain 
      patients have a faster auditory memory trace decay than HCs.
FAU - Fan, Lu
AU  - Fan L
AD  - CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of 
      Sciences, Beijing, 100101, P. R. China.
AD  - Department of Psychology, University of Chinese Academy of Sciences, Beijing, 
      100049, P. R. China.
FAU - Sun, Ya-Bin
AU  - Sun YB
AUID- ORCID: 0000-0001-6487-8419
AD  - CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of 
      Sciences, Beijing, 100101, P. R. China.
AD  - Department of Psychology, University of Chinese Academy of Sciences, Beijing, 
      100049, P. R. China.
FAU - Sun, Ze-Kun
AU  - Sun ZK
AD  - CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of 
      Sciences, Beijing, 100101, P. R. China.
AD  - Department of Psychology, University of Chinese Academy of Sciences, Beijing, 
      100049, P. R. China.
FAU - Wang, Ning
AU  - Wang N
AD  - CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of 
      Sciences, Beijing, 100101, P. R. China.
AD  - Department of Psychology, University of Chinese Academy of Sciences, Beijing, 
      100049, P. R. China.
FAU - Luo, Fei
AU  - Luo F
AD  - CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of 
      Sciences, Beijing, 100101, P. R. China.
AD  - Department of Psychology, University of Chinese Academy of Sciences, Beijing, 
      100049, P. R. China.
FAU - Yu, Feng
AU  - Yu F
AD  - Department of Neurosurgery, Chinese PLA General Hospital of Jinan Military 
      Command, Jinan, 250031, P. R. China. yufeng.yf@163.com.
FAU - Wang, Jin-Yan
AU  - Wang JY
AD  - CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of 
      Sciences, Beijing, 100101, P. R. China. wangjy@psych.ac.cn.
AD  - Department of Psychology, University of Chinese Academy of Sciences, Beijing, 
      100049, P. R. China. wangjy@psych.ac.cn.
LA  - eng
GR  - 31671140/National Natural Science Foundation of China (National Science 
      Foundation of China)/International
GR  - 31171067/National Natural Science Foundation of China (National Science 
      Foundation of China)/International
GR  - 31471061/National Natural Science Foundation of China (National Science 
      Foundation of China)/International
GR  - 31271092/National Natural Science Foundation of China (National Science 
      Foundation of China)/International
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20181023
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
SB  - IM
MH  - Acoustic Stimulation
MH  - Acute Pain/*physiopathology
MH  - Adult
MH  - Brain/physiopathology
MH  - Chronic Pain/*physiopathology
MH  - Evoked Potentials, Auditory
MH  - Female
MH  - Humans
MH  - Male
MH  - Memory
MH  - Middle Aged
MH  - Reaction Time
MH  - Sensation
PMC - PMC6199271
COIS- The authors declare no competing interests.
EDAT- 2018/10/26 06:00
MHDA- 2019/11/26 06:00
PMCR- 2018/10/23
CRDT- 2018/10/25 06:00
PHST- 2018/04/26 00:00 [received]
PHST- 2018/08/13 00:00 [accepted]
PHST- 2018/10/25 06:00 [entrez]
PHST- 2018/10/26 06:00 [pubmed]
PHST- 2019/11/26 06:00 [medline]
PHST- 2018/10/23 00:00 [pmc-release]
AID - 10.1038/s41598-018-34099-y [pii]
AID - 34099 [pii]
AID - 10.1038/s41598-018-34099-y [doi]
PST - epublish
SO  - Sci Rep. 2018 Oct 23;8(1):15673. doi: 10.1038/s41598-018-34099-y.