PMID- 30353428
OWN - NLM
STAT- MEDLINE
DCOM- 20190128
LR  - 20190128
IS  - 1614-7499 (Electronic)
IS  - 0944-1344 (Linking)
VI  - 25
IP  - 35
DP  - 2018 Dec
TI  - Prevalence and probabilistic health risk assessment of aflatoxins B(1), B(2), 
      G(1), and G(2) in Iranian edible oils.
PG  - 35562-35570
LID - 10.1007/s11356-018-3510-0 [doi]
AB  - The prevalence of aflatoxins (AFs) B(1), B(2), G(1), and G(2) in Iranian edible 
      oils were assessed by immunoaffinity column cleanup and HPLC equipped with a 
      fluorescence detector (HPLC-FLD). Ninety-seven samples including sunflower, 
      canola, refined olive, unrefined olive, frying, and blend oils were collected 
      from eight provinces (n = 15 samples of refined olive oil, n = 15 samples of 
      unrefined olive oil, n = 15 samples of sunflower oil, n = 15 samples of canola 
      oil, n = 17 samples of frying oil, and n = 20 samples of blend oil). Also, cancer 
      risk of aflatoxins in the adults and children due to ingestion of edible oils was 
      estimated via margin of exposure (MOE) estimation in the Monte Carlo simulation 
      (MCS) model. Considering the limit of detection (LOD) of the current study, two 
      unrefined olive oil samples from Zanjan Province were contaminated with AFB(2) in 
      the concentrations of 0.2 and 0.4 ng/g while other samples were free from AFB(1), 
      AFB(2), AFG(1), and AFG(2). This study revealed that about 98% of the collected 
      samples were free from AFs and the concentrations of AFs in the polluted samples 
      were within the standard range suggested by European Commission regulation 
      (20 mug/kg). However, health risk assessment indicated that both adult and 
      children in the Zanjan Province are at considerable liver cancer risk (percentile 
      95% of MOE < 10,000 value). Therefore, national plan to address this issue and 
      strict inspection of edible oil products by the regulatory bodies are suggested.
FAU - Nabizadeh, Samaneh
AU  - Nabizadeh S
AD  - Department of Environmental Health, School of Public Health, Tehran University of 
      Medical Sciences, Tehran, Iran.
FAU - Shariatifar, Nabi
AU  - Shariatifar N
AD  - Department of Environmental Health, School of Public Health, Tehran University of 
      Medical Sciences, Tehran, Iran. nshariati@tums.ac.ir.
FAU - Shokoohi, Esmail
AU  - Shokoohi E
AD  - Department of Basic Science, Ahar Branch, Islamic Azad University, Ahar, Iran.
FAU - Shoeibi, Shahram
AU  - Shoeibi S
AD  - Food and Drug Laboratory Research Center, Food and Drug Organization, Ministry of 
      Health & Medical Education, Tehran, Iran.
FAU - Gavahian, Mohsen
AU  - Gavahian M
AD  - Product and Process Research Center, Food Industry Research and Development 
      Institute, No. 331 Shih-Pin Rd., Hsinchu, 30062, Taiwan, Republic of China.
FAU - Fakhri, Yadolah
AU  - Fakhri Y
AD  - Student Research Committee, Department of Environmental Health Engineering, 
      School of Public Health and Safety, Shahid Beheshti University of Medical 
      Sciences, Tehran, Iran.
FAU - Azari, Ali
AU  - Azari A
AD  - Department of Environmental Health, School of Public Health, Tehran University of 
      Medical Sciences, Tehran, Iran.
AD  - Department of Environmental Health Engineering, School of Public Health, Kashan 
      University of Medical Sciences, Kashan, Iran.
FAU - Mousavi Khaneghah, Amin
AU  - Mousavi Khaneghah A
AUID- ORCID: 0000-0001-5769-0004
AD  - Department of Food Science, Faculty of Food Engineering, University of Campinas 
      (UNICAMP), Campinas, Sao Paulo, Brazil. amin.mousavi@asoiu.edu.az.
AD  - Department of Technology of Chemistry, Azerbaijan State Oil and Industry 
      University, Baku, Azerbaijan. amin.mousavi@asoiu.edu.az.
LA  - eng
GR  - 3240274290/CNPq-TWAS Postgraduate Fellowship/
PT  - Journal Article
DEP - 20181023
PL  - Germany
TA  - Environ Sci Pollut Res Int
JT  - Environmental science and pollution research international
JID - 9441769
RN  - 0 (Aflatoxins)
RN  - 0 (Plant Oils)
RN  - 1DB78J7PUD (aflatoxin G1)
RN  - 2MS0D8WA29 (aflatoxin G2)
RN  - 7SKR7S646P (aflatoxin B2)
RN  - 9N2N2Y55MH (Aflatoxin B1)
SB  - IM
MH  - Adult
MH  - Aflatoxin B1/analysis
MH  - Aflatoxins/*analysis
MH  - Child
MH  - Chromatography, High Pressure Liquid
MH  - Food Contamination/*analysis/statistics & numerical data
MH  - Humans
MH  - Iran
MH  - Limit of Detection
MH  - Plant Oils/*chemistry
MH  - Plants, Edible/chemistry
MH  - Prevalence
MH  - Probability
MH  - Reproducibility of Results
MH  - Risk Assessment
OTO - NOTNLM
OT  - Aflatoxins
OT  - Edible oils
OT  - HPLC-FLD
OT  - Immunoaffinity
OT  - MCS
OT  - Risk assessment
OT  - Unrefined
EDAT- 2018/10/26 06:00
MHDA- 2019/01/29 06:00
CRDT- 2018/10/25 06:00
PHST- 2018/05/10 00:00 [received]
PHST- 2018/10/16 00:00 [accepted]
PHST- 2018/10/26 06:00 [pubmed]
PHST- 2019/01/29 06:00 [medline]
PHST- 2018/10/25 06:00 [entrez]
AID - 10.1007/s11356-018-3510-0 [pii]
AID - 10.1007/s11356-018-3510-0 [doi]
PST - ppublish
SO  - Environ Sci Pollut Res Int. 2018 Dec;25(35):35562-35570. doi: 
      10.1007/s11356-018-3510-0. Epub 2018 Oct 23.