PMID- 30366620
OWN - NLM
STAT- MEDLINE
DCOM- 20200210
LR  - 20200210
IS  - 1873-4022 (Electronic)
IS  - 1873-4022 (Linking)
VI  - 44
IP  - 3
DP  - 2019 Autumn
TI  - Nasopharyngeal carcinoma radiotherapy with hybrid technique.
PG  - 251-257
LID - S0958-3947(18)30106-7 [pii]
LID - 10.1016/j.meddos.2018.09.003 [doi]
AB  - The aim of the study was to investigate the effect of the Hybrid technique which 
      was created by combining of intensity modulated radiotherapy (IMRT) and 
      volumetric modulated arc therapy (VMAT) for the treatment of nasopharyngeal 
      cancer (NPC) patients. 7 to 9 field IMRT, triple arc VMAT, and Hybrid plans were 
      generated for 10 advanced stage NPC patients. The homogeneity index (HI) and the 
      conformity index (CI) of planning target volumes (PTVs) were calculated for each 
      technique to evaluate the plan quality. The techniques were compared in terms of 
      plan quality, sparing of organs at risk (OARs), monitor units (MUs), and delivery 
      time. Hybrid technique significantly improved the target dose homogeneity and the 
      conformity for PTV70 and PTV60 compared to IMRT and VMAT. Hybrid plans 
      significantly reduced the maximum dose of the brainstem sparing compared to the 
      VMAT plans and also improved the sparing of spinal cord compared to IMRT and 
      VMAT. The MUs and the delivery time of Hybrid plans were found to be between 
      values for IMRT and VMAT plans. Hybrid technique can be useful when IMRT and VMAT 
      techniques are not adequate alone in the treatment of NPC patients.
CI  - Copyright (c) 2018 American Association of Medical Dosimetrists. Published by 
      Elsevier Inc. All rights reserved.
FAU - Akbas, Ugur
AU  - Akbas U
AD  - Division of Medical Physics, Istanbul University Oncology Institute, Istanbul, 
      Turkey. Electronic address: u.akbas@yahoo.com.
FAU - Koksal, Canan
AU  - Koksal C
AD  - Division of Medical Physics, Istanbul University Oncology Institute, Istanbul, 
      Turkey.
FAU - Kesen, Nazmiye Donmez
AU  - Kesen ND
AD  - Division of Medical Physics, Istanbul University Oncology Institute, Istanbul, 
      Turkey.
FAU - Ozkaya, Kubra
AU  - Ozkaya K
AD  - Division of Radiation Oncology, Istanbul University Medical Faculty, Istanbul, 
      Turkey.
FAU - Bilge, Hatice
AU  - Bilge H
AD  - Division of Medical Physics, Istanbul University Oncology Institute, Istanbul, 
      Turkey.
FAU - Altun, Musa
AU  - Altun M
AD  - Division of Radiation Oncology, Istanbul University Medical Faculty, Istanbul, 
      Turkey.
LA  - eng
PT  - Journal Article
DEP - 20181023
PL  - United States
TA  - Med Dosim
JT  - Medical dosimetry : official journal of the American Association of Medical 
      Dosimetrists
JID - 8908862
SB  - IM
MH  - Humans
MH  - Nasopharyngeal Carcinoma/*radiotherapy
MH  - Nasopharyngeal Neoplasms/*radiotherapy
MH  - Organs at Risk
MH  - Radiotherapy Dosage
MH  - Radiotherapy Planning, Computer-Assisted/*methods
MH  - Radiotherapy, Intensity-Modulated/*methods
OTO - NOTNLM
OT  - Hybrid
OT  - IMRT
OT  - Nasopharyngeal cancer
OT  - VMAT
EDAT- 2018/10/28 06:00
MHDA- 2020/02/11 06:00
CRDT- 2018/10/28 06:00
PHST- 2018/07/02 00:00 [received]
PHST- 2018/09/19 00:00 [revised]
PHST- 2018/09/24 00:00 [accepted]
PHST- 2018/10/28 06:00 [pubmed]
PHST- 2020/02/11 06:00 [medline]
PHST- 2018/10/28 06:00 [entrez]
AID - S0958-3947(18)30106-7 [pii]
AID - 10.1016/j.meddos.2018.09.003 [doi]
PST - ppublish
SO  - Med Dosim. 2019 Autumn;44(3):251-257. doi: 10.1016/j.meddos.2018.09.003. Epub 
      2018 Oct 23.