PMID- 30380342 OWN - NLM STAT- MEDLINE DCOM- 20201013 LR - 20201013 IS - 1521-0553 (Electronic) IS - 0894-1939 (Linking) VI - 33 IP - 4 DP - 2020 Apr TI - Effect of Laparoscopic Nerve-Sparing Radical Hysterectomy on Bladder Function Recovery. PG - 381-386 LID - 10.1080/08941939.2018.1502377 [doi] AB - Background: Radical hysterectomy could result in dysfunctions of pelvic organs and a decline in quality of life. Method: 298 patients who had underwent laparoscopic radical hysterectomy were retrospectively analyzed in this study, of which 216 patients had underwent laparoscopic nerve-sparing radical hysterectomy (LNSRH) and 82 had underwent classical laparoscopic radical hysterectomy (LRH). The mean duration of the postoperative catheterization, a questionnaire and an urodynamic examination were used to assess the bladder functions. Results: The mean duration of the postoperative catheterization in the LNSRH group was shorter than that in the LRH group (13 days versus 18 days, p < 0.01). The incidences of tension urinary incontinence, postoperative voiding time and dysuria symptoms in the LNSRH group, but not in the LRH group, had recovered to preoperative levels in the following 6 months. The frequency of nocturnal urination had recovered to preoperative level at 12 months post-operation in the LNSRH group. The maximum flow rate (MFR), average flow rate (AFR), first voiding sense (FVS), maximum voiding sense (MVS) and maximum detrusor pressure (MDP) in the LNSRH group were better than those in the LRH group (p < 0.05), and patients in the LRH group suffered much more frequently from tension urinary incontinence, prolonged urination time, dysuria and urinary endless compared with those in the LNSRH group (p < 0.05). Conclusion: LNSRH can effectively retain the bladder function, but we should pay attention to the invasion of peripheral nerves. FAU - Liu, Qing AU - Liu Q AD - Department of Gynaecological Oncology, Ren Ji Hospital, School of Medicine, Shanghai JiaoTong University, Shanghai, People's Republic of China. FAU - Li, Peiquan AU - Li P AD - Department of Gynaecological Oncology, Ren Ji Hospital, School of Medicine, Shanghai JiaoTong University, Shanghai, People's Republic of China. FAU - Sun, Yuxin AU - Sun Y AD - Department of Gynaecological Oncology, Ren Ji Hospital, School of Medicine, Shanghai JiaoTong University, Shanghai, People's Republic of China. FAU - Zhang, Shu AU - Zhang S AD - Department of Gynecology and Obstetrics, Ren Ji Hospital, School of Medicine, Shanghai JiaoTong University, Shanghai, People's Republic of China. FAU - Liu, Kaijiang AU - Liu K AUID- ORCID: 0000-0002-1816-3372 AD - Department of Gynaecological Oncology, Ren Ji Hospital, School of Medicine, Shanghai JiaoTong University, Shanghai, People's Republic of China. LA - eng PT - Journal Article DEP - 20181031 PL - United States TA - J Invest Surg JT - Journal of investigative surgery : the official journal of the Academy of Surgical Research JID - 8809255 SB - IM CIN - J Invest Surg. 2020 Apr;33(4):387-388. PMID: 30388913 MH - Female MH - Humans MH - Hysterectomy/adverse effects/*methods MH - Laparoscopy/adverse effects/*methods MH - Neoplasm Invasiveness/prevention & control MH - Organ Sparing Treatments/adverse effects/*methods MH - Peripheral Nerves/pathology/*physiology/surgery MH - Quality of Life MH - Recovery of Function/physiology MH - Retrospective Studies MH - Treatment Outcome MH - Urinary Bladder/innervation/*physiology MH - Urodynamics MH - Uterine Cervical Neoplasms/pathology/*surgery OTO - NOTNLM OT - LNSRH OT - bladder function OT - peripheral nerves OT - radical hysterectomy EDAT- 2018/11/01 06:00 MHDA- 2020/10/21 06:00 CRDT- 2018/11/01 06:00 PHST- 2018/11/01 06:00 [pubmed] PHST- 2020/10/21 06:00 [medline] PHST- 2018/11/01 06:00 [entrez] AID - 10.1080/08941939.2018.1502377 [doi] PST - ppublish SO - J Invest Surg. 2020 Apr;33(4):381-386. doi: 10.1080/08941939.2018.1502377. Epub 2018 Oct 31.