PMID- 30386149
OWN - NLM
STAT- MEDLINE
DCOM- 20190430
LR  - 20221207
IS  - 2005-8330 (Electronic)
IS  - 1229-6929 (Print)
IS  - 1229-6929 (Linking)
VI  - 19
IP  - 6
DP  - 2018 Nov-Dec
TI  - Size-Specific Dose Estimation In the Korean Lung Cancer Screening Project: Does a 
      32-cm Diameter Phantom Represent a Standard-Sized Patient in Korean Population?
PG  - 1179-1186
LID - 10.3348/kjr.2018.19.6.1179 [doi]
AB  - OBJECTIVE: The purposes of this study were to evaluate size-specific dose 
      estimate (SSDE) of low-dose CT (LDCT) in the Korean Lung Cancer Screening 
      (K-LUCAS) project and to determine whether CT protocols from Western countries 
      are appropriate for lung cancer screening in Korea. MATERIALS AND METHODS: For 
      participants (n = 256, four institutions) of K-LUCAS pilot study, volume CT dose 
      index (CTDI(vol)) using a 32-cm diameter reference phantom was compared with 
      SSDE, which was recalculated from CTDI(vol) using size-dependent conversion 
      factor (f-size) based on the body size, as described in the American Association 
      of Physicists in Medicine Report 204. This comparison was subsequently assessed 
      by body mass index (BMI) levels (underweight/normal vs. overweight/obese), and 
      automatic exposure control (AEC) adaptation (yes/no). RESULTS: Size-specific dose 
      estimate was higher than CTDI(vol) (2.22 +/- 0.75 mGy vs. 1.67 +/- 0.60 mGy, p < 
      0.001), since the f-size was larger than 1.0 for all participants. The ratio of 
      SSDE to CTDI(vol) was higher in lower BMI groups; 1.26, 1.37, 1.43, and 1.53 in 
      the obese (n = 103), overweight (n = 70), normal (n = 75), and underweight (n = 
      4), respectively. The ratio of SSDE to CTDI(vol) was greater in standard-sized 
      participants than in large-sized participants independent of AEC adaptation; with 
      AEC, SSDE/CTDI(vol) in large- vs. standard-sized participants: 1.30 +/- 0.08 vs. 
      1.44 +/- 0.08 (p < 0.001) and without AEC, 1.32 +/- 0.08 vs. 1.42 +/- 0.06 (p < 0.001). 
      CONCLUSION: Volume CT dose index based on a reference phantom underestimates 
      radiation exposure of LDCT in standard-sized Korean participants. The optimal 
      radiation dose limit needs to be verified for standard-sized Korean participants.
FAU - Kim, Eun Young
AU  - Kim EY
AD  - Department of Radiology, Gachon University Gil Medical Center, Incheon 21565, 
      Korea.
FAU - Kim, Tae Jung
AU  - Kim TJ
AD  - Department of Radiology and Center for Imaging Science, Samsung Medical Center, 
      Sungkyunkwan University School of Medicine, Seoul 06351, Korea.
FAU - Goo, Jin Mo
AU  - Goo JM
AD  - Department of Radiology, Seoul National University College of Medicine, Seoul 
      03080, Korea.
FAU - Kim, Hyae Young
AU  - Kim HY
AD  - Department of Diagnostic Radiology, National Cancer Center, Goyang 10408, Korea.
FAU - Lee, Ji Won
AU  - Lee JW
AD  - Department of Radiology, Pusan National University School of Medicine and Medical 
      Research Institute, Pusan National University Hospital, Busan 49241, Korea.
FAU - Lee, Soojung
AU  - Lee S
AD  - Department of Radiology, Chungbuk National University Hospital, Cheongju 28644, 
      Korea.
FAU - Lim, Jun-Tae
AU  - Lim JT
AD  - Cancer Early Detection Branch, National Cancer Control Institute, National Cancer 
      Center, Goyang 10408, Korea.
FAU - Kim, Yeol
AU  - Kim Y
AD  - Cancer Early Detection Branch, National Cancer Control Institute, National Cancer 
      Center, Goyang 10408, Korea.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20181018
PL  - Korea (South)
TA  - Korean J Radiol
JT  - Korean journal of radiology
JID - 100956096
SB  - IM
MH  - Aged
MH  - Asian People
MH  - Body Mass Index
MH  - Early Detection of Cancer
MH  - Female
MH  - Humans
MH  - Lung Neoplasms/*diagnosis/diagnostic imaging
MH  - Male
MH  - Middle Aged
MH  - Phantoms, Imaging
MH  - Pilot Projects
MH  - *Radiation Dosage
MH  - Republic of Korea
MH  - Smoking
MH  - Tomography, X-Ray Computed/instrumentation/*methods/standards
PMC - PMC6201978
OTO - NOTNLM
OT  - Early detection
OT  - Low-dose CT
OT  - Radiation dosage
OT  - Radiation dose
EDAT- 2018/11/06 06:00
MHDA- 2019/05/01 06:00
PMCR- 2018/11/01
CRDT- 2018/11/03 06:00
PHST- 2018/04/09 00:00 [received]
PHST- 2018/06/09 00:00 [accepted]
PHST- 2018/11/03 06:00 [entrez]
PHST- 2018/11/06 06:00 [pubmed]
PHST- 2019/05/01 06:00 [medline]
PHST- 2018/11/01 00:00 [pmc-release]
AID - 10.3348/kjr.2018.19.6.1179 [doi]
PST - ppublish
SO  - Korean J Radiol. 2018 Nov-Dec;19(6):1179-1186. doi: 10.3348/kjr.2018.19.6.1179. 
      Epub 2018 Oct 18.