PMID- 30394715 OWN - NLM STAT- MEDLINE DCOM- 20200219 LR - 20200219 IS - 1827-1898 (Electronic) IS - 0031-0808 (Linking) VI - 61 IP - 3 DP - 2019 Sep TI - Competence in navigation and guided transbronchial biopsy for peripheral pulmonary lesions. PG - 280-289 LID - 10.23736/S0031-0808.18.03568-1 [doi] AB - Options for non-surgical tissue diagnosis of the peripheral nodule include CT scan-guided TTNA, fluoroscopy-guided bronchoscopy, radial endobronchial ultrasound (EBUS), electromagnetic navigation bronchoscopy (ENB), and virtual bronchoscopy navigation (VBN). For physicians who choose to pursue non-surgical biopsy, the decision to perform CT scan-guided or ultrasound-guided TTNA, conventional bronchoscopy or bronchoscopy guided by EBUS, ENB, or VBN will depend on a number of factors. CT scan-guided TTNA is preferable for nodules located near the chest wall or for deeper lesions, provided that there is no need to go through the fissures and there is no surrounding emphysema. Ultrasound-guided TTNA requires contact between the lesion and the costal pleura. Bronchoscopic techniques are preferable for nodules >/=2 cm located near a patent bronchus, or in individuals at high risk for pneumothorax following TTNA. In most other situations, operator experience should guide the decision. Trainees must possess a perfect knowledge of anatomy and be fully competent in the interpretation of imaging (CT with contrast medium and PET) and have a thorough knowledge of navigation technology in all its complexities. Practical training can be performed on animal, cadaver or plastic models. In the last years, to improve diagnostic yield, navigational bronchoscopy has attracted significant attention. FAU - Livi, Vanina AU - Livi V AD - Pneumologia Interventistica Interaziendale, Policlinico S. Orsola Malpighi, Maggiore Hospital, Bologna, Italy - vanina.livi@aosp.bo.it. FAU - Barisione, Emanuela AU - Barisione E AD - UOC Pneumologia, Ospedale Policlinico San Martino, Genoa, Italy. FAU - Zuccatosta, Lina AU - Zuccatosta L AD - Operative Unit of Pneumology, Ospedali Riuniti University Hospital, Ancona, Italy. FAU - Romagnoli, Micaela AU - Romagnoli M AD - Operative Unit of Interventional Pneumology, Policlinico Sant'Orsola-Malpighi Hospital, Bologna, Italy. FAU - Pratico, Alessia AU - Pratico A AD - Operative Unit of Pneumology, Perugia University Hospital, Perugia, Italy. FAU - Michieletto, Lucio AU - Michieletto L AD - Operative Unit of Pneumology, Ospedale dell'Angelo, Mestre, Venice, Italy. FAU - Mancino, Laura AU - Mancino L AD - Operative Unit of Pneumology, Ospedale dell'Angelo, Mestre, Venice, Italy. FAU - Corbetta, Lorenzo AU - Corbetta L AD - Operative Unit of Interventional Pneumology, University of Florence, Florence, Italy. LA - eng PT - Journal Article PT - Review DEP - 20181031 PL - Italy TA - Panminerva Med JT - Panminerva medica JID - 0421110 RN - 0 (Contrast Media) SB - IM MH - Biopsy/*methods MH - Bronchi/*diagnostic imaging/pathology MH - Bronchoscopy/*education MH - *Clinical Competence MH - Contrast Media MH - Endosonography/methods MH - Fluoroscopy/methods MH - Humans MH - Lung/pathology MH - Lung Diseases/*diagnosis MH - Positron-Emission Tomography MH - Pulmonary Medicine/*education MH - Tomography, X-Ray Computed MH - Ultrasonography EDAT- 2018/11/06 06:00 MHDA- 2020/02/20 06:00 CRDT- 2018/11/06 06:00 PHST- 2018/11/06 06:00 [pubmed] PHST- 2020/02/20 06:00 [medline] PHST- 2018/11/06 06:00 [entrez] AID - S0031-0808.18.03568-1 [pii] AID - 10.23736/S0031-0808.18.03568-1 [doi] PST - ppublish SO - Panminerva Med. 2019 Sep;61(3):280-289. doi: 10.23736/S0031-0808.18.03568-1. Epub 2018 Oct 31.