PMID- 30396551
OWN - NLM
STAT- MEDLINE
DCOM- 20190320
LR  - 20190320
IS  - 1556-5653 (Electronic)
IS  - 0015-0282 (Linking)
VI  - 110
IP  - 6
DP  - 2018 Nov
TI  - International Committee for Monitoring Assisted Reproductive Technology: world 
      report on assisted reproductive technology, 2011.
PG  - 1067-1080
LID - S0015-0282(18)30549-1 [pii]
LID - 10.1016/j.fertnstert.2018.06.039 [doi]
AB  - OBJECTIVE: To report the utilization, effectiveness, and safety of practices in 
      assisted reproductive technology (ART) globally in 2011 and assess global trends 
      over time. DESIGN: Retrospective, cross-sectional survey on the utilization, 
      effectiveness, and safety of ART procedures performed globally during 2011. 
      SETTING: Sixty-five countries and 2,560 ART clinics. PATIENT(S): Women and men 
      undergoing ART procedures. INTERVENTION(S): All ART. MAIN OUTCOME MEASURE(S): The 
      ART cycles and outcomes on country-by-country, regional, and global levels. 
      Aggregate country data were processed and analyzed based on methods developed by 
      the International Committee for Monitoring Assisted Reproductive Technology 
      (ICMART). RESULT(S): A total of 1,115,272 ART cycles were reported for the 
      treatment year 2011. Imputing data for nonreporting clinics, 1,643,912 cycles 
      resulted in >394,662 babies, excluding People's Republic of China. The best 
      estimate of global utilization including People's Republic of China is 
      approximately 2.0 million cycles and 0.5 million babies. From 2010 to 2011, the 
      number of reported aspiration and frozen ET cycles increased 13.1% and 13.8%, 
      respectively. The proportion of women aged >/=40 years undergoing nondonor ART 
      increased from 23.2% in 2010 to 24.0% in 2011. As a percentage of nondonor 
      aspiration cycles, intracytoplasmic sperm injection (ICSI) decreased slightly 
      from 67.4% in 2010 to 66.5% in 2011. The IVF/ICSI combined delivery rates per 
      fresh aspiration and frozen ET cycles were 19.8% and 21.4%, respectively. In 
      fresh nondonor cycles, single ET increased from 30.0% in 2010 to 31.4% in 2011, 
      whereas the average number of transferred embryos decreased from 1.95 in 2010 to 
      1.91 in 2011-again with wide country variation. The rates of twin deliveries 
      after fresh nondonor transfers decreased from 20.4% in 2010 to 19.6% in 2011; the 
      triplet rate decreased from 1.1%-0.9%. In frozen ET cycles performed in 2011, 
      single ET was 51.6%, with an average of 1.59 embryos transferred and twin and 
      triplet rates were 11.1% and 0.4%, respectively. The cumulative delivery rate per 
      aspiration increased from 27.1% in 2010 to 28.0% in 2011. Fresh IVF/ICSI carried 
      a perinatal mortality rate per 1,000 births of 21.0 in 2010 and 16.3 in 2011. 
      This compared with a perinatal mortality rate after frozen ET of 14.6 per 1,000 
      births in 2010 and 8.6 in 2011. The data presented depend on the quality and 
      completeness of data submitted by individual countries. This report covers 
      approximately two-thirds of'world ART activity. CONCLUSION(S): Global ART 
      utilization, effectiveness, and safety increased between 2010 and 2011.
CI  - Copyright (c) 2018 American Society for Reproductive Medicine. Published by 
      Elsevier Inc. All rights reserved.
FAU - Adamson, G David
AU  - Adamson GD
AD  - International Committee for Monitoring Assisted Reproductive Technologies, 
      Cupertino, Stanford University School of Medicine, Palo Alto, and University of 
      California School of Medicine, San Francisco, California. Electronic address: 
      gdadamson@arcfertility.com.
FAU - de Mouzon, Jacques
AU  - de Mouzon J
AD  - Institut National de la Sante et de la Recherche Medicale Service de Gynecologie 
      Obstetrique II et de Medecine de la Reproduction, Groupe Hospitalier Cochin-Saint 
      Vincet de Paul, Paris, France.
FAU - Chambers, Georgina M
AU  - Chambers GM
AD  - National Perinatal Epidemiology and Statistics Unit, Centre for Big Data Research 
      in Health, School of Women's and Children's Health, University of New South 
      Wales, Sydney, Australia.
FAU - Zegers-Hochschild, Fernando
AU  - Zegers-Hochschild F
AD  - Clinica las Condes and Program of Ethics and Public Policies in Human 
      Reproduction, University Diego Portales, Santiago, Chile.
FAU - Mansour, Ragaa
AU  - Mansour R
AD  - Egyptian IVF-ET Center, Cairo, Egypt.
FAU - Ishihara, Osamu
AU  - Ishihara O
AD  - Department of Obstetrics and Gynaecology, Saitama Medical University, Moroyama, 
      Japan.
FAU - Banker, Manish
AU  - Banker M
AD  - Nova IVI Fertility, Ahmedabad Gujarat, India.
FAU - Dyer, Silke
AU  - Dyer S
AD  - Department of Obstetrics & Gynaecology Groote Schuur Hospital and Faculty of 
      Health Sciences, University of Cape Town, Cape Town, South Africa.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Fertil Steril
JT  - Fertility and sterility
JID - 0372772
SB  - IM
CIN - Fertil Steril. 2018 Nov;110(6):1032-1033. PMID: 30396542
MH  - Adult
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - *Internationality
MH  - Pregnancy
MH  - Pregnancy Rate/*trends
MH  - *Registries
MH  - Reproductive Techniques, Assisted/*trends
MH  - Research Report/*trends
MH  - Retrospective Studies
OTO - NOTNLM
OT  - Assisted reproductive technology
OT  - IVF/ICSI outcome
OT  - frozen embryo transfer
OT  - multiple births
OT  - registry
EDAT- 2018/11/07 06:00
MHDA- 2019/03/21 06:00
CRDT- 2018/11/07 06:00
PHST- 2018/05/11 00:00 [received]
PHST- 2018/06/18 00:00 [revised]
PHST- 2018/06/26 00:00 [accepted]
PHST- 2018/11/07 06:00 [entrez]
PHST- 2018/11/07 06:00 [pubmed]
PHST- 2019/03/21 06:00 [medline]
AID - S0015-0282(18)30549-1 [pii]
AID - 10.1016/j.fertnstert.2018.06.039 [doi]
PST - ppublish
SO  - Fertil Steril. 2018 Nov;110(6):1067-1080. doi: 10.1016/j.fertnstert.2018.06.039.