PMID- 30402810
OWN - NLM
STAT- MEDLINE
DCOM- 20190529
LR  - 20190529
IS  - 1572-8781 (Electronic)
IS  - 1387-2176 (Linking)
VI  - 20
IP  - 4
DP  - 2018 Nov 6
TI  - The microfabrication of mold for polymer microfluidic devices with Zr-based 
      metallic glass.
PG  - 96
LID - 10.1007/s10544-018-0342-0 [doi]
AB  - Polymer microfluidic devices are used for many purposes such as microarrays and 
      biochips. The key tool for manufacturing these chips in bulk is an appropriate 
      mold. However, the popular material for making molds is nickel or nickel alloys, 
      which have low stiffness and wear out easily. Zr-based metallic glass is a 
      promising material for micro- or nanomolds because it has good mechanical 
      properties and can be easily formed with high precision. In this paper, Zr-based 
      metallic glass is proposed for use as micromold insert to make poly-(methyl 
      methacrylate) (PMMA) microfluidic devices. Our experiments show that they have 
      good feature integrity and replication quality. Microchannels we fabricated using 
      these replicas did not leak and had good flow performance. Zr-based metallic 
      glass can greatly ease the manufacture of plastic microfluidic devices for 
      research and commercial applications.
FAU - Zhang, Xiang
AU  - Zhang X
AUID- ORCID: 0000-0002-6416-558X
AD  - School of Mechanics & Engineering Science, Zhengzhou University, Zhengzhou, 
      450001, China. zhangxiang@zzu.edu.cn.
AD  - National Center for International Joint Research of Micro-Nano Molding 
      Technology, Zhengzhou University, Zhengzhou, 450001, China. 
      zhangxiang@zzu.edu.cn.
AD  - Key Laboratory for Micro Molding Technology of Henan Province, Zhengzhou 
      University, Zhengzhou, 450001, China. zhangxiang@zzu.edu.cn.
FAU - Li, Haotong
AU  - Li H
AD  - School of Mechanics & Engineering Science, Zhengzhou University, Zhengzhou, 
      450001, China.
AD  - National Center for International Joint Research of Micro-Nano Molding 
      Technology, Zhengzhou University, Zhengzhou, 450001, China.
AD  - Key Laboratory for Micro Molding Technology of Henan Province, Zhengzhou 
      University, Zhengzhou, 450001, China.
FAU - Wang, Zhenxing
AU  - Wang Z
AD  - School of Mechanics & Engineering Science, Zhengzhou University, Zhengzhou, 
      450001, China.
AD  - National Center for International Joint Research of Micro-Nano Molding 
      Technology, Zhengzhou University, Zhengzhou, 450001, China.
AD  - Key Laboratory for Micro Molding Technology of Henan Province, Zhengzhou 
      University, Zhengzhou, 450001, China.
FAU - Chen, Xueye
AU  - Chen X
AD  - College of Mechanical Engineering and Automation, Liaoning University of 
      Technology, Jinzhou, 121001, China.
FAU - Li, Qian
AU  - Li Q
AD  - School of Mechanics & Engineering Science, Zhengzhou University, Zhengzhou, 
      450001, China. qianli@zzu.edu.cn.
AD  - National Center for International Joint Research of Micro-Nano Molding 
      Technology, Zhengzhou University, Zhengzhou, 450001, China. qianli@zzu.edu.cn.
AD  - Key Laboratory for Micro Molding Technology of Henan Province, Zhengzhou 
      University, Zhengzhou, 450001, China. qianli@zzu.edu.cn.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20181106
PL  - United States
TA  - Biomed Microdevices
JT  - Biomedical microdevices
JID - 100887374
RN  - 0 (Polymers)
RN  - C6V6S92N3C (Zirconium)
SB  - IM
MH  - Equipment Design
MH  - Glass/*chemistry
MH  - Injections
MH  - *Lab-On-A-Chip Devices
MH  - Mechanical Phenomena
MH  - Polymers/*chemistry
MH  - Zirconium/*chemistry
OTO - NOTNLM
OT  - Bulk metallic glass
OT  - Micro mold insert
OT  - Microstructure replication
OT  - Polymer micro molding
EDAT- 2018/11/08 06:00
MHDA- 2019/05/30 06:00
CRDT- 2018/11/08 06:00
PHST- 2018/11/08 06:00 [entrez]
PHST- 2018/11/08 06:00 [pubmed]
PHST- 2019/05/30 06:00 [medline]
AID - 10.1007/s10544-018-0342-0 [pii]
AID - 10.1007/s10544-018-0342-0 [doi]
PST - epublish
SO  - Biomed Microdevices. 2018 Nov 6;20(4):96. doi: 10.1007/s10544-018-0342-0.