PMID- 30407263
OWN - NLM
STAT- MEDLINE
DCOM- 20200409
LR  - 20200409
IS  - 2380-0194 (Electronic)
IS  - 2380-0186 (Linking)
VI  - 32
IP  - 2
DP  - 2019 Mar
TI  - Does Gender Influence Postoperative Outcomes in Minimally Invasive Transforaminal 
      Lumbar Interbody Fusion?
PG  - E107-E111
LID - 10.1097/BSD.0000000000000735 [doi]
AB  - STUDY DESIGN: Retrospective cohort. OBJECTIVE: The objective of this study was to 
      determine if an association exists between gender and postoperative improvements 
      in patient-reported outcomes (PRO) measures following minimally invasive 
      transforaminal lumbar interbody fusion (MIS TLIF). SUMMARY OF BACKGROUND DATA: 
      Current spine literature presents conflicting findings regarding the influence of 
      gender on clinical outcomes. METHODS: Patients undergoing primary, single-level 
      MIS TLIF were retrospectively reviewed. PRO measures including Oswestry 
      Disability Index (ODI) and Visual Analog Scale (VAS) back and leg pain scores 
      were collected preoperatively and 6-week, 12-week, and 6-month postoperatively. 
      Rates of minimum clinically important difference (MCID) achievement were 
      determined at 6-months postoperative. Statistical analysis was performed using 
      Pearson chi analysis or Student t test. RESULTS: In total, 169 patients, 40.83% 
      females and 59.17% males, were included. Females experienced greater inpatient 
      pain scores than males (POD 0: 5.30 vs. 4.69, P=0.041; POD 1: 4.80 vs. 4.13, 
      P=0.019). Females demonstrated significantly greater ODI (43.77 vs. 36.22; 
      P=0.002) and VAS leg (6.20 vs. 5.27; P=0.039) scores than males. No differences 
      in postoperative improvements in ODI, VAS back or VAS leg pain scores were 
      identified between genders, with exception to females demonstrating greater 
      improvement in VAS leg pain at 6 months postoperatively (female: -4.40 vs. male: 
      -3.32; P=0.033). Furthermore, no differences in MCID achievement for PROs were 
      identified between cohorts. CONCLUSIONS: Females demonstrated greater 
      preoperative pain and disability as well as inpatient VAS pain scores compared to 
      males. Furthermore, gender was not associated with differences in length of stay, 
      perioperative complication rates, or narcotics consumption. Improvements in pain 
      and disability, as well as rates of MCID achievement were similar between 
      genders. These findings suggest that gender is not associated with surgical or 
      clinical outcomes and should not be used as a predictor of outcomes following MIS 
      TLIF. LEVEL OF EVIDENCE: Level III.
FAU - Khechen, Benjamin
AU  - Khechen B
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL.
FAU - Haws, Brittany E
AU  - Haws BE
FAU - Patel, Dil V
AU  - Patel DV
FAU - Cardinal, Kaitlyn L
AU  - Cardinal KL
FAU - Guntin, Jordan A
AU  - Guntin JA
FAU - Singh, Kern
AU  - Singh K
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Clin Spine Surg
JT  - Clinical spine surgery
JID - 101675083
SB  - IM
MH  - Disability Evaluation
MH  - Female
MH  - Humans
MH  - Lumbar Vertebrae/*surgery
MH  - Male
MH  - Middle Aged
MH  - *Minimally Invasive Surgical Procedures
MH  - Pain, Postoperative/etiology
MH  - Patient Reported Outcome Measures
MH  - Perioperative Care
MH  - Postoperative Period
MH  - *Sex Characteristics
MH  - *Spinal Fusion/adverse effects
MH  - Treatment Outcome
MH  - Visual Analog Scale
EDAT- 2018/11/09 06:00
MHDA- 2020/04/10 06:00
CRDT- 2018/11/09 06:00
PHST- 2018/11/09 06:00 [pubmed]
PHST- 2020/04/10 06:00 [medline]
PHST- 2018/11/09 06:00 [entrez]
AID - 10.1097/BSD.0000000000000735 [doi]
PST - ppublish
SO  - Clin Spine Surg. 2019 Mar;32(2):E107-E111. doi: 10.1097/BSD.0000000000000735.