PMID- 30427281 OWN - NLM STAT- MEDLINE DCOM- 20200616 LR - 20200616 IS - 1545-9632 (Electronic) IS - 1545-9624 (Linking) VI - 16 IP - 2 DP - 2019 Feb TI - Collection of airborne ultrafine cellulose nanocrystals by impinger with an efficiency mimicking deposition in the human respiratory system. PG - 141-150 LID - 10.1080/15459624.2018.1540876 [doi] AB - As cellulose nanocrystals (CNCs) are increasing in production, establishing safe workplace practices in industry will be paramount to their continued use and growth. Particles other than CNCs with similar high aspect ratios have exhibited toxicity on inhalation. Safeguards are needed to monitor concentrations of CNCs in air in industrial and laboratory settings to protect workers. However, because of their size, morphology, and chemical makeup, CNCs are difficult to characterize and differentiate from other dust and cellulose products. This work is focused on developing an effective method of characterizing the concentration of airborne ultrafine CNCs that may deposit in the respiratory tract. CNCs were tagged with rhodamine b (RhB-CNCs) for improved visualization and characterized using UV-vis spectroscopy (UV-vis), transmission electron microscopy (TEM), and dynamic light scattering (DLS), then aerosolized and collected via a novel method using plastic impingers. Concentration of RhB-CNCs was measured using UV-vis and scanning mobility particle sizer (SMPS). The plastic impinger with 3D-printed nozzle collected airborne CNCs at an efficiency that improves upon commercially available impingers for relevant particle sizes. FAU - Roberts, Rose AU - Roberts R AD - a Virginia Polytechnic Institute and State University - Materials Science and Engineering , Blacksburg , Virginia , United States. FAU - Gettz, Kevin AU - Gettz K AD - b University of Iowa - Department of Occupational and Environmental Health , Iowa City , Iowa , United States. FAU - Stebounova, Larissa V AU - Stebounova LV AUID- ORCID: 0000-0002-1223-8492 AD - b University of Iowa - Department of Occupational and Environmental Health , Iowa City , Iowa , United States. FAU - Anne Shatkin, Jo AU - Anne Shatkin J AD - c Vireo Advisors, LLC , Boston , Massachusetts , United States. FAU - Peters, Thomas AU - Peters T AUID- ORCID: 0000-0002-1698-8856 AD - b University of Iowa - Department of Occupational and Environmental Health , Iowa City , Iowa , United States. FAU - Johan Foster, E AU - Johan Foster E AUID- ORCID: 0000-0002-4103-8510 AD - a Virginia Polytechnic Institute and State University - Materials Science and Engineering , Blacksburg , Virginia , United States. LA - eng PT - Journal Article DEP - 20190301 PL - England TA - J Occup Environ Hyg JT - Journal of occupational and environmental hygiene JID - 101189458 RN - 0 (Particulate Matter) RN - 0 (Rhodamines) RN - 9004-34-6 (Cellulose) RN - K7G5SCF8IL (rhodamine B) SB - IM MH - Cellulose/*analysis MH - Environmental Monitoring/*instrumentation/methods MH - *Nanoparticles MH - Particulate Matter/*analysis MH - Rhodamines MH - Staining and Labeling/methods OTO - NOTNLM OT - Airborne OT - cellulose OT - nanocellulose OT - nanomaterials OT - nanoparticle EDAT- 2018/11/15 06:00 MHDA- 2020/06/17 06:00 CRDT- 2018/11/15 06:00 PHST- 2018/11/15 06:00 [pubmed] PHST- 2020/06/17 06:00 [medline] PHST- 2018/11/15 06:00 [entrez] AID - 10.1080/15459624.2018.1540876 [doi] PST - ppublish SO - J Occup Environ Hyg. 2019 Feb;16(2):141-150. doi: 10.1080/15459624.2018.1540876. Epub 2019 Mar 1.