PMID- 30428343
OWN - NLM
STAT- MEDLINE
DCOM- 20191210
LR  - 20200124
IS  - 2211-1247 (Electronic)
VI  - 25
IP  - 7
DP  - 2018 Nov 13
TI  - Two B-Box Domain Proteins, BBX18 and BBX23, Interact with ELF3 and Regulate 
      Thermomorphogenesis in Arabidopsis.
PG  - 1718-1728.e4
LID - S2211-1247(18)31649-8 [pii]
LID - 10.1016/j.celrep.2018.10.060 [doi]
AB  - Plants coordinate their growth and developmental programs with various endogenous 
      signals and environmental challenges. Phytochrome interacting factor 4 (PIF4) 
      plays a critical positive role in thermoresponsive gene expression and hypocotyl 
      growth in Arabidopsis, whereas early flowering 3 (ELF3) negatively regulates the 
      activity of PIF4 at elevated temperatures. However, it is unknown how ELF3 
      activity is regulated at warm temperatures. Here, we report the identification of 
      B-box 18 (BBX18) and BBX23 as important thermomorphogenesis regulators in 
      Arabidopsis. BBX18 and BBX23 mutations result in reduced thermoresponsive 
      hypocotyl elongation. In contrast, BBX18 overexpression promotes hypocotyl growth 
      at elevated temperatures, which depends on either PIF4 or constitutive 
      photomorphogenic 1 (COP1). BBX18 and BBX23 interact with ELF3 or COP1. Knocking 
      out BBX18 and BBX23 increases ELF3 abundance under normal and warm temperature 
      conditions. The expression of multiple thermoresponsive genes is impaired in both 
      a PIF4 mutant and a BBX18/BBX23 double mutant. Thus, our findings reveal an 
      important role of B-box proteins during thermomorphogenesis and provide insights 
      into our understanding of how warm temperature signals regulate ELF3 activity and 
      PIF4-dependent genes.
CI  - Copyright (c) 2018 The Author(s). Published by Elsevier Inc. All rights reserved.
FAU - Ding, Lan
AU  - Ding L
AD  - State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan 
      University, Shanghai 200433, China; State Key Laboratory of Plant Physiology and 
      Biochemistry, College of Life Sciences, Zhejiang University, Hangzhou 310027, 
      China.
FAU - Wang, Shuo
AU  - Wang S
AD  - State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan 
      University, Shanghai 200433, China.
FAU - Song, Ze-Ting
AU  - Song ZT
AD  - State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan 
      University, Shanghai 200433, China; State Key Laboratory of Plant Physiology and 
      Biochemistry, College of Life Sciences, Zhejiang University, Hangzhou 310027, 
      China.
FAU - Jiang, Yupei
AU  - Jiang Y
AD  - State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan 
      University, Shanghai 200433, China.
FAU - Han, Jia-Jia
AU  - Han JJ
AD  - State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan 
      University, Shanghai 200433, China; State Key Laboratory of Plant Physiology and 
      Biochemistry, College of Life Sciences, Zhejiang University, Hangzhou 310027, 
      China.
FAU - Lu, Sun-Jie
AU  - Lu SJ
AD  - State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan 
      University, Shanghai 200433, China.
FAU - Li, Lin
AU  - Li L
AD  - State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan 
      University, Shanghai 200433, China.
FAU - Liu, Jian-Xiang
AU  - Liu JX
AD  - State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan 
      University, Shanghai 200433, China; State Key Laboratory of Plant Physiology and 
      Biochemistry, College of Life Sciences, Zhejiang University, Hangzhou 310027, 
      China. Electronic address: jianxiangliu@zju.edu.cn.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Cell Rep
JT  - Cell reports
JID - 101573691
RN  - 0 (AT4G10240 protein, Arabidopsis)
RN  - 0 (Arabidopsis Proteins)
RN  - 0 (At2g21320 protein, Arabidopsis)
RN  - 0 (DNA-Binding Proteins)
RN  - 0 (ELF3 protein, Arabidopsis)
RN  - 0 (Transcription Factors)
SB  - IM
MH  - Arabidopsis/genetics/*growth & development/*metabolism
MH  - Arabidopsis Proteins/genetics/*metabolism
MH  - DNA-Binding Proteins/genetics/*metabolism
MH  - Gene Expression Regulation, Developmental
MH  - Gene Expression Regulation, Plant
MH  - *Morphogenesis
MH  - *Temperature
MH  - Transcription Factors/genetics/*metabolism
OTO - NOTNLM
OT  - B-box
OT  - BBX23
OT  - BBX28
OT  - COP1
OT  - ELF3
OT  - PIF4
OT  - thermomorphogenesis
EDAT- 2018/11/15 06:00
MHDA- 2019/12/18 06:00
CRDT- 2018/11/15 06:00
PHST- 2018/05/13 00:00 [received]
PHST- 2018/09/25 00:00 [revised]
PHST- 2018/10/15 00:00 [accepted]
PHST- 2018/11/15 06:00 [entrez]
PHST- 2018/11/15 06:00 [pubmed]
PHST- 2019/12/18 06:00 [medline]
AID - S2211-1247(18)31649-8 [pii]
AID - 10.1016/j.celrep.2018.10.060 [doi]
PST - ppublish
SO  - Cell Rep. 2018 Nov 13;25(7):1718-1728.e4. doi: 10.1016/j.celrep.2018.10.060.