PMID- 30444893
OWN - NLM
STAT- MEDLINE
DCOM- 20190416
LR  - 20190416
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 13
IP  - 11
DP  - 2018
TI  - Association between body mass index and mortality in the Korean elderly: A 
      nationwide cohort study.
PG  - e0207508
LID - 10.1371/journal.pone.0207508 [doi]
LID - e0207508
AB  - The objective of this study was to investigate the relationship between body mass 
      index (BMI) and mortality in the elderly. This study was a nation-wide 
      population-based retrospective cohort study of the National Health Insurance 
      System-Senior Database (NHIS-SD). In this study, a total of 75,856 subjects were 
      identified and selected from among 251,593 individuals aged >/= 65 years who 
      underwent health screening at least once between 2009 and 2012 and who had no 
      history of diabetes, cardiovascular disease, stroke, cancer, or chronic 
      obstructive pulmonary disease (COPD). The subjects of this study were followed-up 
      until 2013 to identify the total mortality and the cause-specific mortality of 6 
      groups divided according to BMI. The hazard ratio (HR) by reference group (23 </= 
      BMI < 25 kg/m2) of each group was calculated. A significant increase in the HR 
      with a decreased BMI was observed in the group with a BMI < 23 kg/m2, whereas the 
      HR in the group with a BMI >/= 25 kg/m2 was not significantly different than that 
      of the reference group (23 </= BMI < 25 kg/m2). This pattern was also seen in the 
      subgroup analyses in relation to age, smoking history, alcohol use, exercise 
      level, and socioeconomic status. In this study, we found that a low BMI was a 
      risk factor for death in the elderly and that no significant difference in 
      mortality was seen in the elderly with a BMI of 25 or over. In terms of an 
      optimal BMI in the elderly, it is important to maintain an appropriately healthy 
      range of BMI with the aim of preventing weight loss.
FAU - Lee, Seung-Hyun
AU  - Lee SH
AD  - Department of Family Medicine, Korea University, College of Medicine, Seoul, 
      Republic of Korea.
FAU - Kim, Do-Hoon
AU  - Kim DH
AUID- ORCID: 0000-0001-7421-4501
AD  - Department of Family Medicine, Korea University, College of Medicine, Seoul, 
      Republic of Korea.
FAU - Park, Joo-Hyun
AU  - Park JH
AD  - Department of Family Medicine, Korea University, College of Medicine, Seoul, 
      Republic of Korea.
FAU - Kim, Shinhye
AU  - Kim S
AD  - Department of Family Medicine, Korea University, College of Medicine, Seoul, 
      Republic of Korea.
FAU - Choi, Moonyoung
AU  - Choi M
AD  - Department of Family Medicine, Korea University, College of Medicine, Seoul, 
      Republic of Korea.
FAU - Kim, Hyonchong
AU  - Kim H
AD  - Department of Family Medicine, Korea University, College of Medicine, Seoul, 
      Republic of Korea.
FAU - Seul, Da Eun
AU  - Seul DE
AD  - Department of Family Medicine, Korea University, College of Medicine, Seoul, 
      Republic of Korea.
FAU - Park, Soo Gyeong
AU  - Park SG
AD  - Department of Family Medicine, Korea University, College of Medicine, Seoul, 
      Republic of Korea.
FAU - Jung, Jin-Hyung
AU  - Jung JH
AD  - Department of Biostatistics, Catholic University College of Medicine, Seoul, 
      Republic of Korea.
FAU - Han, Kyungdo
AU  - Han K
AD  - Department of Biostatistics, Catholic University College of Medicine, Seoul, 
      Republic of Korea.
FAU - Park, Young-Gyu
AU  - Park YG
AD  - Department of Biostatistics, Catholic University College of Medicine, Seoul, 
      Republic of Korea.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20181116
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - *Body Mass Index
MH  - *Databases, Factual
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - *Mortality
MH  - Republic of Korea/epidemiology
MH  - Retrospective Studies
MH  - Risk Factors
PMC - PMC6239300
COIS- The authors have declared that no competing interests exist.
EDAT- 2018/11/18 06:00
MHDA- 2019/04/17 06:00
PMCR- 2018/11/16
CRDT- 2018/11/17 06:00
PHST- 2017/10/05 00:00 [received]
PHST- 2018/11/01 00:00 [accepted]
PHST- 2018/11/17 06:00 [entrez]
PHST- 2018/11/18 06:00 [pubmed]
PHST- 2019/04/17 06:00 [medline]
PHST- 2018/11/16 00:00 [pmc-release]
AID - PONE-D-17-35966 [pii]
AID - 10.1371/journal.pone.0207508 [doi]
PST - epublish
SO  - PLoS One. 2018 Nov 16;13(11):e0207508. doi: 10.1371/journal.pone.0207508. 
      eCollection 2018.