PMID- 30469018
OWN - NLM
STAT- MEDLINE
DCOM- 20190501
LR  - 20190501
IS  - 1873-4499 (Electronic)
IS  - 0899-7071 (Linking)
VI  - 54
DP  - 2019 Mar-Apr
TI  - Clinical metric for differentiating intracranial hemangiopericytomas from 
      meningiomas using diffusion weighted MRI.
PG  - 1-5
LID - S0899-7071(18)30288-2 [pii]
LID - 10.1016/j.clinimag.2018.10.018 [doi]
AB  - PURPOSE: Intracranial Hemangiopericytomas (IHP) are dural based tumors that 
      frequently recur/metastasize. Unfortunately, their imaging appearance overlaps 
      significantly with more benign meningiomas. We evaluated the use of diffusion 
      weighted imaging (DWI) to differentiate IHP from meningioma. METHODS: We compared 
      MRI of IHP tumors (WHO Grades II/III) (n = 20) to meningioma (n = 48, WHO Grade 
      I/II). FINDINGS: ADC values differed between IHP (1.05 x 10-3 mm2/s) and 
      meningiomas (0.89 x 10-3 mm2/s) (p = 0.05). Normalized ADC ratios (nADC), 
      differed between IHP and meningiomas (1.30 vs 1.07, p = 0.03). CONCLUSION: 
      Importantly, a nADC cutoff of >1.3 was specific (96%) but not sensitive (35%) for 
      identifying IHP.
CI  - Copyright (c) 2018 Elsevier Inc. All rights reserved.
FAU - El-Ali, Alexander M
AU  - El-Ali AM
AD  - Department of Radiology, University of Pittsburgh Medical Center, 200 Lothrop 
      Street, Suite 200 East Wing, Pittsburgh, PA 15213, USA.
FAU - Agarwal, Vikas
AU  - Agarwal V
AD  - Department of Radiology, University of Pittsburgh Medical Center, 200 Lothrop 
      Street, Suite 200 East Wing, Pittsburgh, PA 15213, USA. Electronic address: 
      agarwalv@upmc.edu.
FAU - Thomas, Andrew
AU  - Thomas A
AD  - Riverside Radiology and Interventional Associates, Inc., 3525 Olentangy River R., 
      Suite 5362, Columbus, OH 43214, USA.
FAU - Hamilton, Ronald L
AU  - Hamilton RL
AD  - Department of Pathology, Division of Neuropathology, University of Pittsburgh 
      Medical Center, 3550 Terrace Street, S724.1 Scaife Hall, Pittsburgh, PA 15261, 
      USA.
FAU - Filippi, Christopher G
AU  - Filippi CG
AD  - Department of Radiology, Donald and Barbara Zucker School of Medicine at 
      Hofstra/Northwell, Lenox Hill Hospital, 100 East 77th Street, New York, NY 10075, 
      USA.
LA  - eng
PT  - Journal Article
DEP - 20181101
PL  - United States
TA  - Clin Imaging
JT  - Clinical imaging
JID - 8911831
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Brain Neoplasms/*diagnosis/diagnostic imaging/pathology
MH  - Diagnosis, Differential
MH  - Diffusion Magnetic Resonance Imaging/*methods
MH  - Female
MH  - Hemangiopericytoma/*diagnosis/diagnostic imaging/pathology
MH  - Humans
MH  - Magnetic Resonance Imaging/methods
MH  - Male
MH  - Meningeal Neoplasms/*diagnosis/diagnostic imaging/pathology
MH  - Meningioma/*diagnosis/diagnostic imaging/pathology
MH  - Middle Aged
MH  - Sensitivity and Specificity
MH  - Young Adult
OTO - NOTNLM
OT  - Brain tumor
OT  - Diffusion weighted imaging
OT  - Intracranial hemangiopericytoma
OT  - MRI
OT  - Meningioma
EDAT- 2018/11/24 06:00
MHDA- 2019/05/02 06:00
CRDT- 2018/11/24 06:00
PHST- 2018/01/05 00:00 [received]
PHST- 2018/07/25 00:00 [revised]
PHST- 2018/10/22 00:00 [accepted]
PHST- 2018/11/24 06:00 [pubmed]
PHST- 2019/05/02 06:00 [medline]
PHST- 2018/11/24 06:00 [entrez]
AID - S0899-7071(18)30288-2 [pii]
AID - 10.1016/j.clinimag.2018.10.018 [doi]
PST - ppublish
SO  - Clin Imaging. 2019 Mar-Apr;54:1-5. doi: 10.1016/j.clinimag.2018.10.018. Epub 2018 
      Nov 1.