PMID- 30473974
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 10
IP  - 9
DP  - 2018 Sep 21
TI  - Thromboprophylaxis in Intensive Care Unit Patients: A Literature Review.
PG  - e3341
LID - 10.7759/cureus.3341 [doi]
LID - e3341
AB  - Thromboembolism is a major complication in hospitalized patients. Intensive care 
      unit (ICU) patients have a greater risk of thrombotic events due to additional 
      risk factors such as immobilization, mechanical ventilation, and central 
      catheters. The diagnosis and management of deep vein thrombosis (DVT) and 
      pulmonary embolism (PE) in critically ill patients are challenging and these 
      conditions are associated with high mortality. Medical thromboprophylaxis with 
      low molecular weight heparin (LMWH) as well as unfractionated heparin (UFH) has 
      been shown to reduce the incidence of thromboembolic events in such patients. For 
      patients with high risk of bleeding, mechanical thromboprophylaxis can be 
      used. Literature database was conducted on Medline for articles published up to 
      2018 using particular search terms such as thromboprophylaxis and venous 
      thromboembolism in ICU patients. The following review summarizes the existing 
      data regarding thromboprophylaxis in ICU patients with special consideration to 
      the use of mechanical prophylaxis and pharmacologic prophylaxis using heparin 
      products.
FAU - Ejaz, Amna
AU  - Ejaz A
AD  - Internal Medicine, King Edward Medical University/Mayo Hospital, Lahore, PAK.
FAU - Ahmed, Munis M
AU  - Ahmed MM
AD  - Internal Medicine, King Edward Medical University/Mayo Hospital, Lahore, PAK.
FAU - Tasleem, Azka
AU  - Tasleem A
AD  - Internal Medicine, King Edward Medical University/Mayo Hospital, Lahore, PAK.
FAU - Rafay Khan Niazi, Muhammad
AU  - Rafay Khan Niazi M
AD  - Internal Medicine, King Edward Medical University/Mayo Hospital, Lahore, PAK.
FAU - Ahsraf, Muhammad Farhan
AU  - Ahsraf MF
AD  - Internal Medicine, King Edward Medical University/Mayo Hospital, Lahore, PAK.
FAU - Ahmad, Imama
AU  - Ahmad I
AD  - Internal Medicine, King Edward Medical University/Mayo Hospital, Lahore, PAK.
FAU - Zakir, Asma
AU  - Zakir A
AD  - Internal Medicine, King Edward Medical University/Mayo Hospital, Lahore, PAK.
FAU - Raza, Awais
AU  - Raza A
AD  - Internal Medicine, King Edward Medical University/Mayo Hospital, Lahore, PAK.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20180921
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC6248708
OTO - NOTNLM
OT  - intensive care unit(icu)
OT  - prophylaxis
OT  - thromboprophylaxis
OT  - venous thromboembolism
COIS- The authors have declared that no competing interests exist.
EDAT- 2018/11/27 06:00
MHDA- 2018/11/27 06:01
PMCR- 2018/09/21
CRDT- 2018/11/27 06:00
PHST- 2018/11/27 06:00 [entrez]
PHST- 2018/11/27 06:00 [pubmed]
PHST- 2018/11/27 06:01 [medline]
PHST- 2018/09/21 00:00 [pmc-release]
AID - 10.7759/cureus.3341 [doi]
PST - epublish
SO  - Cureus. 2018 Sep 21;10(9):e3341. doi: 10.7759/cureus.3341.