PMID- 30474282 OWN - NLM STAT- MEDLINE DCOM- 20200416 LR - 20200416 IS - 1097-0274 (Electronic) IS - 0271-3586 (Linking) VI - 62 IP - 1 DP - 2019 Jan TI - Occupational rhinitis, asthma, and contact urticaria from IgE-mediated allergy to pork. PG - 80-84 LID - 10.1002/ajim.22921 [doi] AB - We describe four cases of slaughterhouse workers with occupational immediate allergy to raw pork allergens, confirmed by positive skin prick testing and specific immunoglobulin E (IgE) antibodies. Our first patient was diagnosed with occupational asthma from raw pork allergens. Two patients were diagnosed with occupational rhinitis caused by raw pork allergens, which was confirmed by a nasal provocation test. One of these also had occupational contact urticaria caused by raw pork meat. We were unable to diagnose an occupational respiratory or skin disease in the fourth patient, despite signs of immediate sensitization to raw pork meat from occupational exposure. Based on proper diagnoses, measures to prevent allergen exposure were taken, which led to the improvement of symptoms in these four patients. The present patient cases highlight the importance of recognition of early signs of occupational allergy and identification of causative allergens in order to allow avoidance of allergens, with the aim of preventing persistence and worsening of symptoms. CI - (c) 2018 Wiley Periodicals, Inc. FAU - Jungewelter, Soile AU - Jungewelter S AUID- ORCID: 0000-0003-3592-1072 AD - Finnish Institute of Occupational Health (FIOH), Helsinki, Finland. FAU - Airaksinen, Liisa AU - Airaksinen L AD - Finnish Institute of Occupational Health (FIOH), Helsinki, Finland. FAU - Pesonen, Maria AU - Pesonen M AD - Finnish Institute of Occupational Health (FIOH), Helsinki, Finland. LA - eng GR - None./International PT - Case Reports PT - Journal Article DEP - 20181125 PL - United States TA - Am J Ind Med JT - American journal of industrial medicine JID - 8101110 RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Abattoirs MH - Adult MH - Animals MH - Asthma/diagnosis MH - Asthma, Occupational/diagnosis MH - Female MH - Humans MH - Immunoglobulin E/blood MH - Male MH - Middle Aged MH - Occupational Diseases/*diagnosis/immunology/prevention & control MH - Occupational Exposure/*adverse effects/prevention & control MH - Red Meat MH - Rhinitis/diagnosis MH - Skin Tests MH - Swine MH - Urticaria/diagnosis OTO - NOTNLM OT - immediate allergy OT - nasal provocation test OT - pork meat OT - skin prick test OT - slaughterhouse work EDAT- 2018/11/27 06:00 MHDA- 2020/04/17 06:00 CRDT- 2018/11/27 06:00 PHST- 2018/11/02 00:00 [accepted] PHST- 2018/11/27 06:00 [pubmed] PHST- 2020/04/17 06:00 [medline] PHST- 2018/11/27 06:00 [entrez] AID - 10.1002/ajim.22921 [doi] PST - ppublish SO - Am J Ind Med. 2019 Jan;62(1):80-84. doi: 10.1002/ajim.22921. Epub 2018 Nov 25.