PMID- 30474868
OWN - NLM
STAT- MEDLINE
DCOM- 20190507
LR  - 20231012
IS  - 1346-8138 (Electronic)
IS  - 0385-2407 (Print)
IS  - 0385-2407 (Linking)
VI  - 46
IP  - 1
DP  - 2019 Jan
TI  - Metabolic syndrome and psoriatic arthritis among patients with psoriasis 
      vulgaris: Quality of life and prevalence.
PG  - 3-10
LID - 10.1111/1346-8138.14706 [doi]
AB  - Interest has increased in comorbidities associated with psoriasis and their 
      effects on health-related quality of life (HRQoL). This study aimed to evaluate 
      the prevalence of metabolic syndrome (MetS) and psoriatic arthritis (PsA) and to 
      investigate HRQoL and the prevalence of hypertension, type 2 diabetes mellitus 
      (T2DM), obesity and dyslipidemia. In a cross-sectional design, patients diagnosed 
      with plaque psoriasis answered an interview and standardized questionnaires 
      (Dermatology Life Quality Index questionnaire [DLQI], 36-Item Short Form Health 
      Survey [SF-36] and EuroQol Five-Dimension Questionnaire Three-Level version 
      [EQ-5D-3L]). Physical examination and several tests to assess desired outcomes 
      were performed by a dermatologist and a rheumatologist during three visits. The 
      prevalence of MetS and PsA was 50.0% and 41.8%, respectively. Dyslipidemia was 
      the most prevalent (74.5%) secondary comorbidity, followed by hypertension 
      (61.8%), obesity (52.5%) and T2DM (30.9%). The mean (standard deviation) DLQI 
      score was 6.5 (6.9), and mean physical and mental SF-36 measures were 45.2 (10.4) 
      and 45.5 (12.3), respectively, and for EQ-5D-3L, mean utility index and EQ-VAS 
      scores were 0.68 (0.27) and 72.7 (19.7), respectively. PsA and MetS are important 
      comorbidities; a reduced HRQoL is noted among plaque psoriasis patients with 
      these comorbidities, emphasizing the relevance of diagnosis and treatment beyond 
      the care of skin lesions.
CI  - (c) 2018 AbbVie Farmaceutica Ltda. The Journal of Dermatology published by John 
      Wiley & Sons Australia, Ltd on behalf of Japanese Dermatological Association.
FAU - Souza, Cacilda S
AU  - Souza CS
AUID- ORCID: 0000-0002-8157-7658
AD  - Faculty of Medicine of Ribeirao Preto/University of Sao Paulo, Sao Paulo, Brazil.
FAU - de Castro, Caio C S
AU  - de Castro CCS
AD  - Hospital of Santa Casa of Curitiba/Pontifical Catholic University of Parana, 
      Curitiba, Brazil.
FAU - Carneiro, Francisca R O
AU  - Carneiro FRO
AD  - University of the State of Para, Belem, Brazil.
FAU - Pinto, Jane M N
AU  - Pinto JMN
AD  - Federal Fluminense University, Niteroi, Brazil.
FAU - Fabricio, Lincoln H Z
AU  - Fabricio LHZ
AD  - Evangelical University Hospital of Curitiba, Curitiba, Brazil.
FAU - Azulay-Abulafia, Luna
AU  - Azulay-Abulafia L
AD  - Institute of Dermatology and Aesthetics of Rio de Janeiro, Rio de Janeiro, 
      Brazil.
FAU - Romiti, Ricardo
AU  - Romiti R
AD  - Department of Dermatology, Hospital das Clinicas, University of Sao Paulo, Sao 
      Paulo, Brazil.
FAU - Cestari, Tania F
AU  - Cestari TF
AD  - Hospital de Clinicas of Porto Alegre/Federal University of Rio Grande do Sul, 
      Porto Alegre, Brazil.
FAU - Suzuki, Claudia E
AU  - Suzuki CE
AD  - AbbVie, Sao Paulo, Brazil.
FAU - Biegun, Priscila M
AU  - Biegun PM
AD  - AbbVie, Sao Paulo, Brazil.
FAU - Guedes, Luciana S
AU  - Guedes LS
AD  - Formerly AbbVie Employee, Sao Paulo, Brazil.
FAU - Oyafuso, Luiza K M
AU  - Oyafuso LKM
AD  - Faculty of Medicine of ABC, Sao Paulo, Brazil.
LA  - eng
GR  - AbbVie/
PT  - Journal Article
PT  - Observational Study
DEP - 20181126
PL  - England
TA  - J Dermatol
JT  - The Journal of dermatology
JID - 7600545
SB  - IM
MH  - Adult
MH  - Arthritis, Psoriatic/*epidemiology
MH  - Brazil/epidemiology
MH  - Comorbidity
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/epidemiology
MH  - Dyslipidemias/epidemiology
MH  - Female
MH  - Humans
MH  - Hypertension/epidemiology
MH  - Male
MH  - Metabolic Syndrome/*epidemiology
MH  - Middle Aged
MH  - Obesity/epidemiology
MH  - Prevalence
MH  - Psoriasis/*epidemiology
MH  - *Quality of Life
MH  - Severity of Illness Index
MH  - Surveys and Questionnaires
PMC - PMC6587528
OTO - NOTNLM
OT  - metabolic syndrome
OT  - psoriasis
OT  - psoriatic arthritis
OT  - quality of life
OT  - systemic disease
EDAT- 2018/11/27 06:00
MHDA- 2019/05/08 06:00
PMCR- 2019/06/21
CRDT- 2018/11/27 06:00
PHST- 2018/03/13 00:00 [received]
PHST- 2018/10/13 00:00 [accepted]
PHST- 2018/11/27 06:00 [pubmed]
PHST- 2019/05/08 06:00 [medline]
PHST- 2018/11/27 06:00 [entrez]
PHST- 2019/06/21 00:00 [pmc-release]
AID - JDE14706 [pii]
AID - 10.1111/1346-8138.14706 [doi]
PST - ppublish
SO  - J Dermatol. 2019 Jan;46(1):3-10. doi: 10.1111/1346-8138.14706. Epub 2018 Nov 26.