PMID- 3048077
OWN - NLM
STAT- MEDLINE
DCOM- 19881027
LR  - 20231213
IS  - 0002-9165 (Print)
IS  - 0002-9165 (Linking)
VI  - 48
IP  - 4
DP  - 1988 Oct
TI  - Glucose and insulin response in diabetic subjects: acute effect of carbohydrate 
      level and the addition of soy polysaccharide in defined-formula diets.
PG  - 1048-52
AB  - This single-meal pilot study compared the plasma glucose and serum insulin 
      response to defined-formula diets with two levels of carbohydrate (CHO) (55% and 
      30% of the kilocalories) with and without added soy polysaccharide (10 g) in 
      subjects with type 2 diabetes mellitus. Subjects received each of the four 
      liquid-formula test meals in a randomly assigned order: 1) high CHO, low fiber 
      (HC, LF), 2) high CHO, high fiber (HC, HF), 3) low CHO, low fiber (LC, LF), and 
      4) low CHO, high fiber (LC, HF). On the day of each test meal the formula was 
      consumed, eight blood samples were drawn for plasma glucose and serum insulin 
      measurements, and a 4-h urine collection was obtained for measuring glucose 
      excretion. Our results showed that area increments under glucose and insulin 
      curves were significantly lower with both low-CHO formulas (p less than 0.001). 
      The addition of soy polysaccharide to the liquid formula did not result in 
      statistically different area increments for glucose or insulin.
FAU - Thomas, B L
AU  - Thomas BL
AD  - General Clinical Research Center, University of Minnesota, Minneapolis.
FAU - Laine, D C
AU  - Laine DC
FAU - Goetz, F C
AU  - Goetz FC
LA  - eng
GR  - RR400/RR/NCRR NIH HHS/United States
PT  - Clinical Trial
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Am J Clin Nutr
JT  - The American journal of clinical nutrition
JID - 0376027
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Insulin)
RN  - 0 (Polysaccharides)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Blood Glucose/*metabolism
MH  - Diabetes Mellitus, Type 2/*blood
MH  - Dietary Carbohydrates/*pharmacology
MH  - Female
MH  - Food, Formulated
MH  - Humans
MH  - Insulin/*blood
MH  - Male
MH  - Middle Aged
MH  - Polysaccharides/*pharmacology
MH  - *Glycine max
EDAT- 1988/10/01 00:00
MHDA- 1988/10/01 00:01
CRDT- 1988/10/01 00:00
PHST- 1988/10/01 00:00 [pubmed]
PHST- 1988/10/01 00:01 [medline]
PHST- 1988/10/01 00:00 [entrez]
AID - 10.1093/ajcn/48.4.1048 [doi]
PST - ppublish
SO  - Am J Clin Nutr. 1988 Oct;48(4):1048-52. doi: 10.1093/ajcn/48.4.1048.