PMID- 30485466
OWN - NLM
STAT- MEDLINE
DCOM- 20191202
LR  - 20191202
IS  - 1525-1594 (Electronic)
IS  - 0160-564X (Linking)
VI  - 43
IP  - 6
DP  - 2019 Jun
TI  - Short-term outcomes of intra-aortic balloon pump combined with venoarterial 
      extracorporeal membrane oxygenation: A systematic review and meta-analysis.
PG  - 561-568
LID - 10.1111/aor.13397 [doi]
AB  - The effectiveness of intra-aortic balloon pump (IABP) combined with venoarterial 
      extracorporeal membrane oxygenation (VA-ECMO) in patients with cardiogenic shock 
      or cardiac arrest remains controversial. The aim of this systematic review and 
      meta-analysis was to investigate the short-term clinical outcomes of IABP 
      combined with VA-ECMO versus VA-ECMO alone. We searched PubMed, Embase, and the 
      Cochrane Library for English language articles published from inception to August 
      18, 2018. Observational studies comparing IABP combined with VA-ECMO with VA-ECMO 
      were considered eligible for the current study. Twelve observational studies with 
      3704 patients were included. In the IABP combined with VA-ECMO group mortality 
      was 59.7%, compared with 65.8% in the VA-ECMO alone group. The risk ratio (RR) 
      for this comparison was 0.90 (95% confidence interval [CI], 0.80-1.02; P = 0.107; 
      59.7% vs. 65.8%). In the one-way sensitivity analysis for estimating the effect 
      of each study on mortality, omission of each study did not make a significant 
      difference. Furthermore, the proportion of patients weaned from VA-ECMO was 
      significantly higher in IABP combined VA-ECMO group than in the VA-ECMO alone 
      group (RR, 1.28; 95% CI, 1.21-1.35; P < 0.001; 77.9% vs. 61.2%). IABP combined 
      with VA-ECMO could improve success rate of weaning from VA-ECMO, but did not 
      reduce in-hospital mortality in patients with cardiogenic shock or cardiac 
      arrest.
CI  - (c) 2019 International Center for Artificial Organs and Transplantation and Wiley 
      Periodicals, Inc.
FAU - Wang, Li
AU  - Wang L
AD  - Department of Anesthesiology, The First Affiliated Hospital of Hebei North 
      College, Hebei, People's Republic of China.
FAU - Xing, Zhen
AU  - Xing Z
AUID- ORCID: 0000-0002-9115-3189
AD  - Department of Anesthesiology, The First Affiliated Hospital of Hebei North 
      College, Hebei, People's Republic of China.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Systematic Review
DEP - 20190102
PL  - United States
TA  - Artif Organs
JT  - Artificial organs
JID - 7802778
SB  - IM
MH  - *Extracorporeal Membrane Oxygenation/methods/mortality
MH  - Heart Arrest/*therapy
MH  - Humans
MH  - *Intra-Aortic Balloon Pumping/methods/mortality
MH  - Odds Ratio
MH  - Shock, Cardiogenic/*therapy
MH  - Treatment Outcome
OTO - NOTNLM
OT  - cardiac arrest
OT  - cardiogenic shock
OT  - extracorporeal membrane oxygenation
OT  - intra-aortic balloon pump
OT  - mortality
EDAT- 2018/11/30 06:00
MHDA- 2019/12/04 06:00
CRDT- 2018/11/29 06:00
PHST- 2018/09/03 00:00 [received]
PHST- 2018/10/14 00:00 [revised]
PHST- 2018/11/19 00:00 [accepted]
PHST- 2018/11/30 06:00 [pubmed]
PHST- 2019/12/04 06:00 [medline]
PHST- 2018/11/29 06:00 [entrez]
AID - 10.1111/aor.13397 [doi]
PST - ppublish
SO  - Artif Organs. 2019 Jun;43(6):561-568. doi: 10.1111/aor.13397. Epub 2019 Jan 2.