PMID- 30489438
OWN - NLM
STAT- MEDLINE
DCOM- 20201111
LR  - 20201111
IS  - 1932-751X (Electronic)
IS  - 1932-7501 (Linking)
VI  - 39
IP  - 6
DP  - 2019 Nov
TI  - Establishing the Minimal Clinically Important Difference for the Hospital Anxiety 
      and Depression Scale in Patients With Cardiovascular Disease.
PG  - E6-E11
LID - 10.1097/HCR.0000000000000379 [doi]
AB  - PURPOSE: The Hospital Anxiety and Depression Scale (HADS) is frequently used by 
      clinicians to assess anxiety and depression in patients with cardiovascular 
      disease; yet, its minimal clinically important difference (MCID) has not been 
      established. The purpose of this study was to establish an MCID for the HADS in 
      patients with cardiovascular disease. METHODS: A sample of 591 patients (74% 
      male; ethnicity = 89% white; mean +/- standard deviation [SD]: age = 63 +/- 10 yr; 
      and body mass index = 29.1 +/- 5.6 kg/m) with cardiovascular disease enrolled in a 
      3-mo cardiac rehabilitation program were included in this study. The MCID for the 
      HADS was estimated using distribution-based methods (ie, standard deviation, 
      effect size, standard error of measurement, and minimal detectable change), 
      anchor-based methods (ie, health transition question, correlation and linear 
      regression, and receiver operating characteristic curve), and Delphi methodology 
      (ie, clinical consensus). RESULTS: A total of 18 MCID values were calculated 
      ranging from 0.81 to 5.21 (Anxiety subscale) and 0.5 to 5.57 (Depression 
      subscale). The final MCID for the HADS, triangulated from the distribution-based, 
      anchor-based, and Delphi-based findings, was 1.7 points. CONCLUSIONS: Our work 
      provides the first estimates of an MCID by triangulating multiple methodologies 
      for the HADS in patients with cardiovascular disease. This MCID may serve as an 
      indicator of treatment success for clinicians and researchers and guide future 
      interventions to improve the mental health of patients with cardiovascular 
      disease.
FAU - Lemay, Kyle R
AU  - Lemay KR
AD  - Division of Cardiac Prevention and Rehabilitation, University of Ottawa Heart 
      Institute, Ottawa, Ontario, Canada (Mr Lemay and Drs Tulloch, Pipe, and Reed); 
      Department of Psychology, Carleton University, Ottawa, Ontario, Canada (Mr Lemay 
      and Dr Pipe); and Faculty of Medicine (Dr Tulloch) and Faculty of Health Sciences 
      (Dr Reed), University of Ottawa, Ottawa, Ontario, Canada.
FAU - Tulloch, Heather E
AU  - Tulloch HE
FAU - Pipe, Andrew L
AU  - Pipe AL
FAU - Reed, Jennifer L
AU  - Reed JL
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Cardiopulm Rehabil Prev
JT  - Journal of cardiopulmonary rehabilitation and prevention
JID - 101291247
SB  - IM
MH  - Anxiety Disorders/*complications/*diagnosis/psychology
MH  - Canada
MH  - Cardiovascular Diseases/*complications/*psychology
MH  - Databases, Factual
MH  - Depressive Disorder/*complications/*diagnosis/psychology
MH  - Female
MH  - Hospitalization
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Minimal Clinically Important Difference
MH  - Retrospective Studies
EDAT- 2018/11/30 06:00
MHDA- 2020/11/12 06:00
CRDT- 2018/11/30 06:00
PHST- 2018/11/30 06:00 [pubmed]
PHST- 2020/11/12 06:00 [medline]
PHST- 2018/11/30 06:00 [entrez]
AID - 10.1097/HCR.0000000000000379 [doi]
PST - ppublish
SO  - J Cardiopulm Rehabil Prev. 2019 Nov;39(6):E6-E11. doi: 
      10.1097/HCR.0000000000000379.