PMID- 30498058
OWN - NLM
STAT- MEDLINE
DCOM- 20200506
LR  - 20210109
IS  - 1468-2044 (Electronic)
IS  - 0003-9888 (Print)
IS  - 0003-9888 (Linking)
VI  - 105
IP  - 2
DP  - 2020 Feb
TI  - Risk factors for permanent childhood hearing impairment.
PG  - 187-189
LID - 10.1136/archdischild-2018-315866 [doi]
AB  - OBJECTIVE: While several perinatal risk factors for permanent childhood hearing 
      impairment (PCHI) are known, association with gestational length remains unclear. 
      We hypothesised that shorter gestational length predicts higher PCHI risk. 
      DESIGN: 19 504 participants from the UK Millennium Cohort Study (born 2000-2002, 
      prior to newborn screening). METHODS: Multivariable discrete-time survival 
      analysis to examine associations between parent-reported PCHI by age 11 years and 
      gestational length, plus other prespecified factors. RESULTS: PCHI affected 2.1 
      per 1000 children (95% CI 1.5 to 3.0) by age 11; however, gestational length did 
      not predict PCHI risk (HR, 95% CI 1.00, 0.98 to 1.03 per day increase). Risk was 
      increased in those with neonatal illness, with or without admission to neonatal 
      care (6.33, 2.27 to 17.63 and 2.62, 1.15 to 5.97, respectively), of Bangladeshi 
      or Pakistani ethnicity (2.78, 1.06 to 7.31) or born to younger mothers (0.92, 
      0.87 to 0.97 per year). CONCLUSION: Neonatal illness, rather than gestational 
      length, predicts PCHI risk. Further research should explore associations with 
      ethnicity.
CI  - (c) Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published 
      by BMJ.
FAU - Butcher, Emma
AU  - Butcher E
AUID- ORCID: 0000-0002-0622-3198
AD  - Life Course Epidemiology and Biostatistics, Great Ormond Street Institute of 
      Child Health, University College London, London, UK.
FAU - Dezateux, Carol
AU  - Dezateux C
AD  - Life Course Epidemiology and Biostatistics, Great Ormond Street Institute of 
      Child Health, University College London, London, UK.
AD  - Centre for Primary Care and Public Health, Barts and the London School of 
      Medicine and Dentistry, Queen Mary University of London, London, UK.
FAU - Knowles, Rachel L
AU  - Knowles RL
AUID- ORCID: 0000-0002-5490-7682
AD  - Life Course Epidemiology and Biostatistics, Great Ormond Street Institute of 
      Child Health, University College London, London, UK.
LA  - eng
GR  - WT_/Wellcome Trust/United Kingdom
GR  - BHF_/British Heart Foundation/United Kingdom
GR  - MRC_/Medical Research Council/United Kingdom
GR  - Chief Scientist Office [UK]/International
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20181128
PL  - England
TA  - Arch Dis Child
JT  - Archives of disease in childhood
JID - 0372434
SB  - IM
MH  - Child
MH  - Female
MH  - Gestational Age
MH  - Hearing Loss/*epidemiology/etiology
MH  - Humans
MH  - Infant, Newborn
MH  - Infant, Newborn, Diseases
MH  - Male
MH  - Prospective Studies
MH  - Risk Assessment
MH  - Risk Factors
PMC - PMC7025723
OTO - NOTNLM
OT  - deafness
OT  - epidemiology
COIS- Competing interests: None declared.
EDAT- 2018/12/01 06:00
MHDA- 2020/05/07 06:00
PMCR- 2020/02/17
CRDT- 2018/12/01 06:00
PHST- 2018/07/16 00:00 [received]
PHST- 2018/10/31 00:00 [revised]
PHST- 2018/11/03 00:00 [accepted]
PHST- 2018/12/01 06:00 [pubmed]
PHST- 2020/05/07 06:00 [medline]
PHST- 2018/12/01 06:00 [entrez]
PHST- 2020/02/17 00:00 [pmc-release]
AID - archdischild-2018-315866 [pii]
AID - 10.1136/archdischild-2018-315866 [doi]
PST - ppublish
SO  - Arch Dis Child. 2020 Feb;105(2):187-189. doi: 10.1136/archdischild-2018-315866. 
      Epub 2018 Nov 28.