PMID- 30499910
OWN - NLM
STAT- MEDLINE
DCOM- 20190514
LR  - 20190514
IS  - 1536-3678 (Electronic)
IS  - 1077-4114 (Linking)
VI  - 41
IP  - 2
DP  - 2019 Mar
TI  - Massive Splenic Infarction in a Child With Sickle Cell Disease on Chronic 
      Transfusion Therapy.
PG  - e79-e82
LID - 10.1097/MPH.0000000000001356 [doi]
AB  - Massive splenic infarction (MSI) is a rare complication of sickle cell disease, 
      as the spleen generally atrophies within the first few years of life. We report a 
      case of MSI in a 12-year-old boy with homozygous sickle cell anemia (Hb SS) whose 
      chronic transfusion therapy resulted in hypersplenism. The occurrence of a 
      complicated MSI in our patient should perhaps further encourage elective 
      splenectomy in such patients, despite known potential perioperative complications 
      and postsplenectomy risks of infection and thrombosis.
FAU - Pereda, Maria A
AU  - Pereda MA
AD  - Departments of Pediatrics.
FAU - Isaac, Jaya
AU  - Isaac J
AD  - Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New 
      Brunswick, NJ.
FAU - Zhang, Yaoping
AU  - Zhang Y
AD  - Departments of Pediatrics.
FAU - Jayakumar, Rajeswari
AU  - Jayakumar R
AD  - Pathology, SUNY Downstate Medical Center, Brooklyn, NY.
FAU - Gupta, Raavi
AU  - Gupta R
AD  - Pathology, SUNY Downstate Medical Center, Brooklyn, NY.
FAU - Miller, Scott T
AU  - Miller ST
AD  - Departments of Pediatrics.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - J Pediatr Hematol Oncol
JT  - Journal of pediatric hematology/oncology
JID - 9505928
SB  - IM
MH  - *Anemia, Sickle Cell/diagnostic imaging/therapy
MH  - *Blood Transfusion
MH  - Child
MH  - Humans
MH  - Male
MH  - *Splenectomy
MH  - *Splenic Infarction/diagnostic imaging/etiology/surgery
MH  - *Transfusion Reaction/diagnostic imaging/surgery
EDAT- 2018/12/01 06:00
MHDA- 2019/05/15 06:00
CRDT- 2018/12/01 06:00
PHST- 2018/12/01 06:00 [pubmed]
PHST- 2019/05/15 06:00 [medline]
PHST- 2018/12/01 06:00 [entrez]
AID - 10.1097/MPH.0000000000001356 [doi]
PST - ppublish
SO  - J Pediatr Hematol Oncol. 2019 Mar;41(2):e79-e82. doi: 
      10.1097/MPH.0000000000001356.